These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 27877888)

  • 41. Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression.
    Davidson CD; Ali NF; Micsenyi MC; Stephney G; Renault S; Dobrenis K; Ory DS; Vanier MT; Walkley SU
    PLoS One; 2009 Sep; 4(9):e6951. PubMed ID: 19750228
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Niemann-Pick C variant detection by altered sphingolipid trafficking and correlation with mutations within a specific domain of NPC1.
    Sun X; Marks DL; Park WD; Wheatley CL; Puri V; O'Brien JF; Kraft DL; Lundquist PA; Patterson MC; Pagano RE; Snow K
    Am J Hum Genet; 2001 Jun; 68(6):1361-72. PubMed ID: 11349231
    [TBL] [Abstract][Full Text] [Related]  

  • 43. δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders.
    Xu M; Liu K; Swaroop M; Porter FD; Sidhu R; Firnkes S; Ory DS; Marugan JJ; Xiao J; Southall N; Pavan WJ; Davidson C; Walkley SU; Remaley AT; Baxa U; Sun W; McKew JC; Austin CP; Zheng W
    J Biol Chem; 2012 Nov; 287(47):39349-60. PubMed ID: 23035117
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Targeting defective sphingosine kinase 1 in Niemann-Pick type C disease with an activator mitigates cholesterol accumulation.
    Newton J; Palladino END; Weigel C; Maceyka M; Gräler MH; Senkal CE; Enriz RD; Marvanova P; Jampilek J; Lima S; Milstien S; Spiegel S
    J Biol Chem; 2020 Jul; 295(27):9121-9133. PubMed ID: 32385114
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Terminal Structure of Triethylene Glycol-Tethered Chains on β-Cyclodextrin-Threaded Polyrotaxanes Dominates Temperature Responsivity and Biointeractions.
    Ohashi M; Tamura A; Yui N
    Langmuir; 2021 Sep; 37(37):11102-11114. PubMed ID: 34478294
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Analytical Characterization of Methyl-β-Cyclodextrin for Pharmacological Activity to Reduce Lysosomal Cholesterol Accumulation in Niemann-Pick Disease Type C1 Cells.
    Li R; Hao J; Fujiwara H; Xu M; Yang S; Dai S; Long Y; Swaroop M; Li C; Vu M; Marugan JJ; Ory DS; Zheng W
    Assay Drug Dev Technol; 2017; 15(4):154-166. PubMed ID: 28631941
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Beneficial effects of primidone in Niemann-Pick disease type C (NPC)-model cells and mice: Reduction of unesterified cholesterol levels in cells and extension of lifespan in mice.
    Ashikawa H; Mogi H; Honda T; Nakamura H; Murayama T
    Eur J Pharmacol; 2021 Apr; 896():173907. PubMed ID: 33503462
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Genistein Activates Transcription Factor EB and Corrects Niemann-Pick C Phenotype.
    Argüello G; Balboa E; Tapia PJ; Castro J; Yañez MJ; Mattar P; Pulgar R; Zanlungo S
    Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33921734
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Synthesis of multi-lactose-appended β-cyclodextrin and its cholesterol-lowering effects in Niemann-Pick type C disease-like HepG2 cells.
    Motoyama K; Nishiyama R; Maeda Y; Higashi T; Ishitsuka Y; Kondo Y; Irie T; Era T; Arima H
    Beilstein J Org Chem; 2017; 13():10-18. PubMed ID: 28179943
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Monitoring the itinerary of lysosomal cholesterol in Niemann-Pick Type C1-deficient cells after cyclodextrin treatment.
    Feltes M; Gale SE; Moores S; Ory DS; Schaffer JE
    J Lipid Res; 2020 Mar; 61(3):403-412. PubMed ID: 31988149
    [TBL] [Abstract][Full Text] [Related]  

  • 51. [Inclusion Solves Insolubility -Translational Research Cycle from Bedside to Bench and Bench to Bedside for Drug Development Targeting Niemann-Pick Disease Type C].
    Irie T
    Yakugaku Zasshi; 2022; 142(4):389-400. PubMed ID: 35370195
    [TBL] [Abstract][Full Text] [Related]  

  • 52. High-content screen for modifiers of Niemann-Pick type C disease in patient cells.
    Pugach EK; Feltes M; Kaufman RJ; Ory DS; Bang AG
    Hum Mol Genet; 2018 Jun; 27(12):2101-2112. PubMed ID: 29659804
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Tailoring the supramolecular structure of aminated polyrotaxanes toward enhanced cellular internalization.
    Yokoyama N; Seo JH; Tamura A; Sasaki Y; Yui N
    Macromol Biosci; 2014 Mar; 14(3):359-68. PubMed ID: 24634263
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Quantitative comparison of the efficacy of various compounds in lowering intracellular cholesterol levels in Niemann-Pick type C fibroblasts.
    Wehrmann ZT; Hulett TW; Huegel KL; Vaughan KT; Wiest O; Helquist P; Goodson H
    PLoS One; 2012; 7(10):e48561. PubMed ID: 23144769
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Cyclodextrin-based tailored polyrotaxanes for highly efficient delivery of the genome-editing molecule.
    Taharabaru T; Kihara T; Obata A; Onodera R; Wen Y; Li J; Motoyama K; Higashi T
    Carbohydr Polym; 2024 Jan; 323():121443. PubMed ID: 37940259
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Nanoparticles containing β-cyclodextrin potentially useful for the treatment of Niemann-Pick C.
    Donida B; Raabe M; Tauffner B; de Farias MA; Machado AZ; Timm F; Kessler RG; Hammerschmidt TG; Reinhardt LS; Brito VB; Portugal RV; Bernardi A; Frozza R; Moura DJ; Giugliani R; Poletto F; Vargas CR
    J Inherit Metab Dis; 2020 May; 43(3):586-601. PubMed ID: 31943253
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease.
    Torres S; Matías N; Baulies A; Nuñez S; Alarcon-Vila C; Martinez L; Nuño N; Fernandez A; Caballeria J; Levade T; Gonzalez-Franquesa A; Garcia-Rovés P; Balboa E; Zanlungo S; Fabrías G; Casas J; Enrich C; Garcia-Ruiz C; Fernández-Checa JC
    Redox Biol; 2017 Apr; 11():60-72. PubMed ID: 27888692
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Activation of mammalian terget of rapamycin kinase and glycogen synthase kinase-3β accompanies abnormal accumulation of cholesterol in fibroblasts from Niemann-Pick type C patients.
    Wos M; Komiażyk M; Pikula S; Tylki-Szymanska A; Bandorowicz-Pikula J
    J Cell Biochem; 2019 Apr; 120(4):6580-6588. PubMed ID: 30390318
    [TBL] [Abstract][Full Text] [Related]  

  • 59. 2-Hydroxypropyl-gamma-cyclodextrin overcomes NPC1 deficiency by enhancing lysosome-ER association and autophagy.
    Singhal A; Krystofiak ES; Jerome WG; Song B
    Sci Rep; 2020 May; 10(1):8663. PubMed ID: 32457374
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Mutations in the leucine zipper motif and sterol-sensing domain inactivate the Niemann-Pick C1 glycoprotein.
    Watari H; Blanchette-Mackie EJ; Dwyer NK; Watari M; Neufeld EB; Patel S; Pentchev PG; Strauss JF
    J Biol Chem; 1999 Jul; 274(31):21861-6. PubMed ID: 10419504
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.