These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

254 related articles for article (PubMed ID: 27878282)

  • 1. The importance of mitochondrial folate enzymes in human colorectal cancer.
    Miyo M; Konno M; Colvin H; Nishida N; Koseki J; Kawamoto K; Tsunekuni K; Nishimura J; Hata T; Takemasa I; Mizushima T; Doki Y; Mori M; Ishii H
    Oncol Rep; 2017 Jan; 37(1):417-425. PubMed ID: 27878282
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The mitochondrial one-carbon metabolic pathway is associated with patient survival in pancreatic cancer.
    Noguchi K; Konno M; Koseki J; Nishida N; Kawamoto K; Yamada D; Asaoka T; Noda T; Wada H; Gotoh K; Sakai D; Kudo T; Satoh T; Eguchi H; Doki Y; Mori M; Ishii H
    Oncol Lett; 2018 Aug; 16(2):1827-1834. PubMed ID: 30008872
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The one-carbon metabolism pathway highlights therapeutic targets for gastrointestinal cancer (Review).
    Konno M; Asai A; Kawamoto K; Nishida N; Satoh T; Doki Y; Mori M; Ishii H
    Int J Oncol; 2017 Apr; 50(4):1057-1063. PubMed ID: 28259896
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2.
    Nishimura T; Nakata A; Chen X; Nishi K; Meguro-Horike M; Sasaki S; Kita K; Horike SI; Saitoh K; Kato K; Igarashi K; Murayama T; Kohno S; Takahashi C; Mukaida N; Yano S; Soga T; Tojo A; Gotoh N
    Oncogene; 2019 Apr; 38(14):2464-2481. PubMed ID: 30532069
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Folate-mediated one-carbon metabolism: a targeting strategy in cancer therapy.
    Yang C; Zhang J; Liao M; Yang Y; Wang Y; Yuan Y; Ouyang L
    Drug Discov Today; 2021 Mar; 26(3):817-825. PubMed ID: 33316375
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mitochondrial translation requires folate-dependent tRNA methylation.
    Morscher RJ; Ducker GS; Li SH; Mayer JA; Gitai Z; Sperl W; Rabinowitz JD
    Nature; 2018 Feb; 554(7690):128-132. PubMed ID: 29364879
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cisplatin inhibits SIRT3-deacetylation MTHFD2 to disturb cellular redox balance in colorectal cancer cell.
    Wan X; Wang C; Huang Z; Zhou D; Xiang S; Qi Q; Chen X; Arbely E; Liu CY; Du P; Yu W
    Cell Death Dis; 2020 Aug; 11(8):649. PubMed ID: 32811824
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation.
    Gustafsson Sheppard N; Jarl L; Mahadessian D; Strittmatter L; Schmidt A; Madhusudan N; Tegnér J; Lundberg EK; Asplund A; Jain M; Nilsson R
    Sci Rep; 2015 Oct; 5():15029. PubMed ID: 26461067
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enzymes of the one-carbon folate metabolism as anticancer targets predicted by survival rate analysis.
    Koseki J; Konno M; Asai A; Colvin H; Kawamoto K; Nishida N; Sakai D; Kudo T; Satoh T; Doki Y; Mori M; Ishii H
    Sci Rep; 2018 Jan; 8(1):303. PubMed ID: 29321536
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.
    Ma J; Stampfer MJ; Giovannucci E; Artigas C; Hunter DJ; Fuchs C; Willett WC; Selhub J; Hennekens CH; Rozen R
    Cancer Res; 1997 Mar; 57(6):1098-102. PubMed ID: 9067278
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer.
    Nilsson R; Jain M; Madhusudhan N; Sheppard NG; Strittmatter L; Kampf C; Huang J; Asplund A; Mootha VK
    Nat Commun; 2014; 5():3128. PubMed ID: 24451681
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Suppression of MTHFD2 in MCF-7 Breast Cancer Cells Increases Glycolysis, Dependency on Exogenous Glycine, and Sensitivity to Folate Depletion.
    Koufaris C; Gallage S; Yang T; Lau CH; Valbuena GN; Keun HC
    J Proteome Res; 2016 Aug; 15(8):2618-25. PubMed ID: 27315223
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitochondrial Methylenetetrahydrofolate Dehydrogenase (MTHFD2) Overexpression Is Associated with Tumor Cell Proliferation and Is a Novel Target for Drug Development.
    Tedeschi PM; Vazquez A; Kerrigan JE; Bertino JR
    Mol Cancer Res; 2015 Oct; 13(10):1361-6. PubMed ID: 26101208
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Relative distribution of folate species is associated with global DNA methylation in human colorectal mucosa.
    Liu J; Hesson LB; Meagher AP; Bourke MJ; Hawkins NJ; Rand KN; Molloy PL; Pimanda JE; Ward RL
    Cancer Prev Res (Phila); 2012 Jul; 5(7):921-9. PubMed ID: 22609762
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Association of dietary and supplemental folate intake and polymorphisms in three FOCM pathway genes with colorectal cancer in a population-based case-control study.
    Ashmore JH; Lesko SM; Muscat JE; Gallagher CJ; Berg AS; Miller PE; Hartman TJ; Lazarus P
    Genes Chromosomes Cancer; 2013 Oct; 52(10):945-53. PubMed ID: 23893618
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Deacetylation of MTHFD2 by SIRT4 senses stress signal to inhibit cancer cell growth by remodeling folate metabolism.
    Zhang F; Wang D; Li J; Su Y; Liu S; Lei QY; Yin M
    J Mol Cell Biol; 2022 Jul; 14(4):. PubMed ID: 35349697
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications.
    Ju HQ; Lu YX; Chen DL; Zuo ZX; Liu ZX; Wu QN; Mo HY; Wang ZX; Wang DS; Pu HY; Zeng ZL; Li B; Xie D; Huang P; Hung MC; Chiao PJ; Xu RH
    J Natl Cancer Inst; 2019 Jun; 111(6):584-596. PubMed ID: 30534944
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ALDH1L1 and ALDH1L2 Folate Regulatory Enzymes in Cancer.
    Krupenko SA; Krupenko NI
    Adv Exp Med Biol; 2018; 1032():127-143. PubMed ID: 30362096
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Folate-mediated one-carbon metabolism genes and interactions with nutritional factors on colorectal cancer risk: Women's Health Initiative Observational Study.
    Cheng TY; Makar KW; Neuhouser ML; Miller JW; Song X; Brown EC; Beresford SA; Zheng Y; Poole EM; Galbraith RL; Duggan DJ; Habermann N; Bailey LB; Maneval DR; Caudill MA; Toriola AT; Green R; Ulrich CM
    Cancer; 2015 Oct; 121(20):3684-91. PubMed ID: 26108676
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Acetylation of aldehyde dehydrogenase ALDH1L2 regulates cellular redox balance and the chemosensitivity of colorectal cancer to 5-fluorouracil.
    Li C; Teng P; Sun S; Cui K; Yao S; Fei B; Ling F; Huang Z
    J Biol Chem; 2023 Sep; 299(9):105090. PubMed ID: 37507016
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.