255 related articles for article (PubMed ID: 27878282)
1. The importance of mitochondrial folate enzymes in human colorectal cancer.
Miyo M; Konno M; Colvin H; Nishida N; Koseki J; Kawamoto K; Tsunekuni K; Nishimura J; Hata T; Takemasa I; Mizushima T; Doki Y; Mori M; Ishii H
Oncol Rep; 2017 Jan; 37(1):417-425. PubMed ID: 27878282
[TBL] [Abstract][Full Text] [Related]
2. The mitochondrial one-carbon metabolic pathway is associated with patient survival in pancreatic cancer.
Noguchi K; Konno M; Koseki J; Nishida N; Kawamoto K; Yamada D; Asaoka T; Noda T; Wada H; Gotoh K; Sakai D; Kudo T; Satoh T; Eguchi H; Doki Y; Mori M; Ishii H
Oncol Lett; 2018 Aug; 16(2):1827-1834. PubMed ID: 30008872
[TBL] [Abstract][Full Text] [Related]
3. The one-carbon metabolism pathway highlights therapeutic targets for gastrointestinal cancer (Review).
Konno M; Asai A; Kawamoto K; Nishida N; Satoh T; Doki Y; Mori M; Ishii H
Int J Oncol; 2017 Apr; 50(4):1057-1063. PubMed ID: 28259896
[TBL] [Abstract][Full Text] [Related]
4. Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2.
Nishimura T; Nakata A; Chen X; Nishi K; Meguro-Horike M; Sasaki S; Kita K; Horike SI; Saitoh K; Kato K; Igarashi K; Murayama T; Kohno S; Takahashi C; Mukaida N; Yano S; Soga T; Tojo A; Gotoh N
Oncogene; 2019 Apr; 38(14):2464-2481. PubMed ID: 30532069
[TBL] [Abstract][Full Text] [Related]
5. Folate-mediated one-carbon metabolism: a targeting strategy in cancer therapy.
Yang C; Zhang J; Liao M; Yang Y; Wang Y; Yuan Y; Ouyang L
Drug Discov Today; 2021 Mar; 26(3):817-825. PubMed ID: 33316375
[TBL] [Abstract][Full Text] [Related]
6. Mitochondrial translation requires folate-dependent tRNA methylation.
Morscher RJ; Ducker GS; Li SH; Mayer JA; Gitai Z; Sperl W; Rabinowitz JD
Nature; 2018 Feb; 554(7690):128-132. PubMed ID: 29364879
[TBL] [Abstract][Full Text] [Related]
7. Cisplatin inhibits SIRT3-deacetylation MTHFD2 to disturb cellular redox balance in colorectal cancer cell.
Wan X; Wang C; Huang Z; Zhou D; Xiang S; Qi Q; Chen X; Arbely E; Liu CY; Du P; Yu W
Cell Death Dis; 2020 Aug; 11(8):649. PubMed ID: 32811824
[TBL] [Abstract][Full Text] [Related]
8. The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation.
Gustafsson Sheppard N; Jarl L; Mahadessian D; Strittmatter L; Schmidt A; Madhusudan N; Tegnér J; Lundberg EK; Asplund A; Jain M; Nilsson R
Sci Rep; 2015 Oct; 5():15029. PubMed ID: 26461067
[TBL] [Abstract][Full Text] [Related]
9. Enzymes of the one-carbon folate metabolism as anticancer targets predicted by survival rate analysis.
Koseki J; Konno M; Asai A; Colvin H; Kawamoto K; Nishida N; Sakai D; Kudo T; Satoh T; Doki Y; Mori M; Ishii H
Sci Rep; 2018 Jan; 8(1):303. PubMed ID: 29321536
[TBL] [Abstract][Full Text] [Related]
10. Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.
Ma J; Stampfer MJ; Giovannucci E; Artigas C; Hunter DJ; Fuchs C; Willett WC; Selhub J; Hennekens CH; Rozen R
Cancer Res; 1997 Mar; 57(6):1098-102. PubMed ID: 9067278
[TBL] [Abstract][Full Text] [Related]
11. Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer.
Nilsson R; Jain M; Madhusudhan N; Sheppard NG; Strittmatter L; Kampf C; Huang J; Asplund A; Mootha VK
Nat Commun; 2014; 5():3128. PubMed ID: 24451681
[TBL] [Abstract][Full Text] [Related]
12. Suppression of MTHFD2 in MCF-7 Breast Cancer Cells Increases Glycolysis, Dependency on Exogenous Glycine, and Sensitivity to Folate Depletion.
Koufaris C; Gallage S; Yang T; Lau CH; Valbuena GN; Keun HC
J Proteome Res; 2016 Aug; 15(8):2618-25. PubMed ID: 27315223
[TBL] [Abstract][Full Text] [Related]
13. Mitochondrial Methylenetetrahydrofolate Dehydrogenase (MTHFD2) Overexpression Is Associated with Tumor Cell Proliferation and Is a Novel Target for Drug Development.
Tedeschi PM; Vazquez A; Kerrigan JE; Bertino JR
Mol Cancer Res; 2015 Oct; 13(10):1361-6. PubMed ID: 26101208
[TBL] [Abstract][Full Text] [Related]
14. Relative distribution of folate species is associated with global DNA methylation in human colorectal mucosa.
Liu J; Hesson LB; Meagher AP; Bourke MJ; Hawkins NJ; Rand KN; Molloy PL; Pimanda JE; Ward RL
Cancer Prev Res (Phila); 2012 Jul; 5(7):921-9. PubMed ID: 22609762
[TBL] [Abstract][Full Text] [Related]
15. Association of dietary and supplemental folate intake and polymorphisms in three FOCM pathway genes with colorectal cancer in a population-based case-control study.
Ashmore JH; Lesko SM; Muscat JE; Gallagher CJ; Berg AS; Miller PE; Hartman TJ; Lazarus P
Genes Chromosomes Cancer; 2013 Oct; 52(10):945-53. PubMed ID: 23893618
[TBL] [Abstract][Full Text] [Related]
16. Deacetylation of MTHFD2 by SIRT4 senses stress signal to inhibit cancer cell growth by remodeling folate metabolism.
Zhang F; Wang D; Li J; Su Y; Liu S; Lei QY; Yin M
J Mol Cell Biol; 2022 Jul; 14(4):. PubMed ID: 35349697
[TBL] [Abstract][Full Text] [Related]
17. Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications.
Ju HQ; Lu YX; Chen DL; Zuo ZX; Liu ZX; Wu QN; Mo HY; Wang ZX; Wang DS; Pu HY; Zeng ZL; Li B; Xie D; Huang P; Hung MC; Chiao PJ; Xu RH
J Natl Cancer Inst; 2019 Jun; 111(6):584-596. PubMed ID: 30534944
[TBL] [Abstract][Full Text] [Related]
18. ALDH1L1 and ALDH1L2 Folate Regulatory Enzymes in Cancer.
Krupenko SA; Krupenko NI
Adv Exp Med Biol; 2018; 1032():127-143. PubMed ID: 30362096
[TBL] [Abstract][Full Text] [Related]
19. Folate-mediated one-carbon metabolism genes and interactions with nutritional factors on colorectal cancer risk: Women's Health Initiative Observational Study.
Cheng TY; Makar KW; Neuhouser ML; Miller JW; Song X; Brown EC; Beresford SA; Zheng Y; Poole EM; Galbraith RL; Duggan DJ; Habermann N; Bailey LB; Maneval DR; Caudill MA; Toriola AT; Green R; Ulrich CM
Cancer; 2015 Oct; 121(20):3684-91. PubMed ID: 26108676
[TBL] [Abstract][Full Text] [Related]
20. Acetylation of aldehyde dehydrogenase ALDH1L2 regulates cellular redox balance and the chemosensitivity of colorectal cancer to 5-fluorouracil.
Li C; Teng P; Sun S; Cui K; Yao S; Fei B; Ling F; Huang Z
J Biol Chem; 2023 Sep; 299(9):105090. PubMed ID: 37507016
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
