These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 27878880)

  • 1. Highly Conformationally Restricted Cyclopropane Tethers with Three-Dimensional Structural Diversity Drastically Enhance the Cell Permeability of Cyclic Peptides.
    Matsui K; Kido Y; Watari R; Kashima Y; Yoshida Y; Shuto S
    Chemistry; 2017 Mar; 23(13):3034-3041. PubMed ID: 27878880
    [TBL] [Abstract][Full Text] [Related]  

  • 2. From Peptides to Peptidomimetics: A Strategy Based on the Structural Features of Cyclopropane.
    Mizuno A; Matsui K; Shuto S
    Chemistry; 2017 Oct; 23(58):14394-14409. PubMed ID: 28632330
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Medicinal Chemical Studies Based on the Theoretical Design of Bioactive Compounds].
    Shuto S
    Yakugaku Zasshi; 2020; 140(3):329-344. PubMed ID: 32115550
    [TBL] [Abstract][Full Text] [Related]  

  • 4. cis-Peptide Bonds: A Key for Intestinal Permeability of Peptides? .
    Marelli UK; Ovadia O; Frank AO; Chatterjee J; Gilon C; Hoffman A; Kessler H
    Chemistry; 2015 Oct; 21(43):15148-52. PubMed ID: 26337831
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Improvement on Permeability of Cyclic Peptide/Peptidomimetic: Backbone
    Li Y; Li W; Xu Z
    Mar Drugs; 2021 May; 19(6):. PubMed ID: 34072121
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of amino acid chirality and the chemical linker on the cell permeation characteristics of cyclic prodrugs of opioid peptides.
    Liederer BM; Fuchs T; Vander Velde D; Siahaan TJ; Borchardt RT
    J Med Chem; 2006 Feb; 49(4):1261-70. PubMed ID: 16480263
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exploring experimental and computational markers of cyclic peptides: Charting islands of permeability.
    Wang CK; Northfield SE; Swedberg JE; Colless B; Chaousis S; Price DA; Liras S; Craik DJ
    Eur J Med Chem; 2015 Jun; 97():202-13. PubMed ID: 25974856
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cyclopropane pipecolic acids as templates for linear and cyclic peptidomimetics: application in the synthesis of an Arg-Gly-Asp (RGD)-containing peptide as an αvβ3 integrin ligand.
    Sernissi L; Petrović M; Scarpi D; Guarna A; Trabocchi A; Bianchini F; Occhiato EG
    Chemistry; 2014 Aug; 20(35):11187-203. PubMed ID: 25069617
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of versatile cis- and trans-dicarbon-substituted chiral cyclopropane units: synthesis of (1S,2R)- and (1R,2R)-2-aminomethyl-1-(1H-imidazol-4-yl)cyclopropanes and their enantiomers as conformationally restricted analogues of histamine.
    Kazuta Y; Matsuda A; Shuto S
    J Org Chem; 2002 Mar; 67(5):1669-77. PubMed ID: 11871901
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and Development of a Cyclic Decapeptide Scaffold with Suitable Properties for Bioavailability and Oral Exposure.
    Fouché M; Schäfer M; Berghausen J; Desrayaud S; Blatter M; Piéchon P; Dix I; Martin Garcia A; Roth HJ
    ChemMedChem; 2016 May; 11(10):1048-59. PubMed ID: 27154275
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonists with an imidazolylcyclopropane structure.
    Watanabe M; Kazuta Y; Hayashi H; Yamada S; Matsuda A; Shuto S
    J Med Chem; 2006 Sep; 49(18):5587-96. PubMed ID: 16942032
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intestinal permeability of cyclic peptides: common key backbone motifs identified.
    Beck JG; Chatterjee J; Laufer B; Kiran MU; Frank AO; Neubauer S; Ovadia O; Greenberg S; Gilon C; Hoffman A; Kessler H
    J Am Chem Soc; 2012 Jul; 134(29):12125-33. PubMed ID: 22737969
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of Flexibility, Lipophilicity, and the Location of Polar Residues on the Passive Membrane Permeability of a Series of Cyclic Decapeptides.
    Wang S; König G; Roth HJ; Fouché M; Rodde S; Riniker S
    J Med Chem; 2021 Sep; 64(17):12761-12773. PubMed ID: 34406766
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and synthesis of cyclopropane-based conformationally restricted GABA analogues as selective inhibitors for betaine/GABA transporter 1.
    Suemasa A; Watanabe M; Kobayashi T; Suzuki H; Fukuda H; Minami M; Shuto S
    Bioorg Med Chem Lett; 2018 Nov; 28(20):3395-3399. PubMed ID: 30177378
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyclopropane-based stereochemical diversity-oriented conformational restriction strategy: histamine H3 and/or H4 receptor ligands with the 2,3-methanobutane backbone.
    Watanabe M; Kobayashi T; Hirokawa T; Yoshida A; Ito Y; Yamada S; Orimoto N; Yamasaki Y; Arisawa M; Shuto S
    Org Biomol Chem; 2012 Jan; 10(4):736-45. PubMed ID: 22120611
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design of cyclic peptides featuring proline predominantly in the cis conformation under physiological conditions.
    Malešević M; Schumann M; Jahreis G; Fischer G; Lücke C
    Chembiochem; 2012 Sep; 13(14):2122-7. PubMed ID: 22969011
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclopropane-Based Peptidomimetics Mimicking Wide-Ranging Secondary Structures of Peptides: Conformational Analysis and Their Use in Rational Ligand Optimization.
    Mizuno A; Kameda T; Kuwahara T; Endoh H; Ito Y; Yamada S; Hasegawa K; Yamano A; Watanabe M; Arisawa M; Shuto S
    Chemistry; 2017 Mar; 23(13):3159-3168. PubMed ID: 28000361
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conformational Flexibility Is a Determinant of Permeability for Cyclosporin.
    Wang CK; Swedberg JE; Harvey PJ; Kaas Q; Craik DJ
    J Phys Chem B; 2018 Mar; 122(8):2261-2276. PubMed ID: 29400464
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Flexibility versus Rigidity for Orally Bioavailable Cyclic Hexapeptides.
    Nielsen DS; Lohman RJ; Hoang HN; Hill TA; Jones A; Lucke AJ; Fairlie DP
    Chembiochem; 2015 Nov; 16(16):2289-93. PubMed ID: 26336864
    [TBL] [Abstract][Full Text] [Related]  

  • 20. N-methylated cyclic pentaalanine peptides as template structures.
    Chatterjee J; Mierke D; Kessler H
    J Am Chem Soc; 2006 Nov; 128(47):15164-72. PubMed ID: 17117868
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.