BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

580 related articles for article (PubMed ID: 27880732)

  • 1. Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid-derived suppressor cells.
    Liu F; Li X; Lu C; Bai A; Bielawski J; Bielawska A; Marshall B; Schoenlein PV; Lebedyeva IO; Liu K
    Oncotarget; 2016 Dec; 7(51):83907-83925. PubMed ID: 27880732
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel off-target effect of tamoxifen--inhibition of acid ceramidase activity in cancer cells.
    Morad SA; Levin JC; Tan SF; Fox TE; Feith DJ; Cabot MC
    Biochim Biophys Acta; 2013 Dec; 1831(12):1657-64. PubMed ID: 23939396
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Autocrine IL6-Mediated Activation of the STAT3-DNMT Axis Silences the TNFα-RIP1 Necroptosis Pathway to Sustain Survival and Accumulation of Myeloid-Derived Suppressor Cells.
    Smith AD; Lu C; Payne D; Paschall AV; Klement JD; Redd PS; Ibrahim ML; Yang D; Han Q; Liu Z; Shi H; Hartney TJ; Nayak-Kapoor A; Liu K
    Cancer Res; 2020 Aug; 80(15):3145-3156. PubMed ID: 32554751
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells.
    Alissafi T; Hatzioannou A; Mintzas K; Barouni RM; Banos A; Sormendi S; Polyzos A; Xilouri M; Wielockx B; Gogas H; Verginis P
    J Clin Invest; 2018 Aug; 128(9):3840-3852. PubMed ID: 29920188
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis.
    Zhu H; Klement JD; Lu C; Redd PS; Yang D; Smith AD; Poschel DB; Zou J; Liu D; Wang PG; Ostrov D; Coant N; Hannun YA; Colby AH; Grinstaff MW; Liu K
    J Immunol; 2021 Mar; 206(6):1395-1404. PubMed ID: 33547170
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interaction of acid ceramidase inhibitor LCL521 with tumor response to photodynamic therapy and photodynamic therapy-generated vaccine.
    Korbelik M; Banáth J; Zhang W; Saw KM; Szulc ZM; Bielawska A; Separovic D
    Int J Cancer; 2016 Sep; 139(6):1372-8. PubMed ID: 27136745
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Staphylococcus aureus α-Toxin Induces Inflammatory Cytokines via Lysosomal Acid Sphingomyelinase and Ceramides.
    Ma J; Gulbins E; Edwards MJ; Caldwell CC; Fraunholz M; Becker KA
    Cell Physiol Biochem; 2017; 43(6):2170-2184. PubMed ID: 29069651
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dose dependent actions of LCL521 on acid ceramidase and key sphingolipid metabolites.
    Bai A; Bielawska A; Rahmaniyan M; Kraveka JM; Bielawski J; Hannun YA
    Bioorg Med Chem; 2018 Dec; 26(23-24):6067-6075. PubMed ID: 30448190
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Blocking autophagy enhances the apoptotic effect of 18β-glycyrrhetinic acid on human sarcoma cells via endoplasmic reticulum stress and JNK activation.
    Shen S; Zhou M; Huang K; Wu Y; Ma Y; Wang J; Ma J; Fan S
    Cell Death Dis; 2017 Sep; 8(9):e3055. PubMed ID: 28933787
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Arsenic trioxide induces programmed cell death through stimulation of ER stress and inhibition of the ubiquitin-proteasome system in human sarcoma cells.
    Chiu HW; Tseng YC; Hsu YH; Lin YF; Foo NP; Guo HR; Wang YJ
    Cancer Lett; 2015 Jan; 356(2 Pt B):762-72. PubMed ID: 25449439
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dysfunctional autophagy following exposure to pro-inflammatory cytokines contributes to pancreatic β-cell apoptosis.
    Lambelet M; Terra LF; Fukaya M; Meyerovich K; Labriola L; Cardozo AK; Allagnat F
    Cell Death Dis; 2018 Jan; 9(2):96. PubMed ID: 29367588
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hepatic carcinoma-associated fibroblasts enhance immune suppression by facilitating the generation of myeloid-derived suppressor cells.
    Deng Y; Cheng J; Fu B; Liu W; Chen G; Zhang Q; Yang Y
    Oncogene; 2017 Feb; 36(8):1090-1101. PubMed ID: 27593937
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Blockade of Myd88 signaling by a novel MyD88 inhibitor prevents colitis-associated colorectal cancer development by impairing myeloid-derived suppressor cells.
    Wang L; Hu D; Xie B; Xie L
    Invest New Drugs; 2022 Jun; 40(3):506-518. PubMed ID: 35089465
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lysosomal ceramide generated by acid sphingomyelinase triggers cytosolic cathepsin B-mediated degradation of X-linked inhibitor of apoptosis protein in natural killer/T lymphoma cell apoptosis.
    Taniguchi M; Ogiso H; Takeuchi T; Kitatani K; Umehara H; Okazaki T
    Cell Death Dis; 2015 Apr; 6(4):e1717. PubMed ID: 25855965
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells.
    Yu L; Wu WK; Gu C; Zhong D; Zhao X; Kong Y; Lin Q; Chan MT; Zhou Z; Liu S
    Oncotarget; 2016 Mar; 7(12):14693-707. PubMed ID: 26910910
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cathepsin inhibition-induced lysosomal dysfunction enhances pancreatic beta-cell apoptosis in high glucose.
    Jung M; Lee J; Seo HY; Lim JS; Kim EK
    PLoS One; 2015; 10(1):e0116972. PubMed ID: 25625842
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Initial autophagic protection switches to disruption of autophagic flux by lysosomal instability during cadmium stress accrual in renal NRK-52E cells.
    Lee WK; Probst S; Santoyo-Sánchez MP; Al-Hamdani W; Diebels I; von Sivers JK; Kerek E; Prenner EJ; Thévenod F
    Arch Toxicol; 2017 Oct; 91(10):3225-3245. PubMed ID: 28321485
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activated hepatic stellate cells promote liver cancer by induction of myeloid-derived suppressor cells through cyclooxygenase-2.
    Xu Y; Zhao W; Xu J; Li J; Hong Z; Yin Z; Wang X
    Oncotarget; 2016 Feb; 7(8):8866-78. PubMed ID: 26758420
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stress-induced apoptosis is impaired in cells with a lysosomal targeting defect but is not affected in cells synthesizing a catalytically inactive cathepsin D.
    Tardy C; Tyynelä J; Hasilik A; Levade T; Andrieu-Abadie N
    Cell Death Differ; 2003 Sep; 10(9):1090-100. PubMed ID: 12934083
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Suppressive role of myeloid-derived suppressor cells (MDSCs) in the microenvironment of breast cancer and targeted immunotherapies.
    Shou D; Wen L; Song Z; Yin J; Sun Q; Gong W
    Oncotarget; 2016 Sep; 7(39):64505-64511. PubMed ID: 27542274
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.