These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 27888140)

  • 1. Designed covalent allosteric modulators: an emerging paradigm in drug discovery.
    Lu S; Zhang J
    Drug Discov Today; 2017 Feb; 22(2):447-453. PubMed ID: 27888140
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Covalent allosteric modulation: An emerging strategy for GPCRs drug discovery.
    Bian Y; Jun JJ; Cuyler J; Xie XQ
    Eur J Med Chem; 2020 Nov; 206():112690. PubMed ID: 32818870
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Allosteric Modulator Discovery: From Serendipity to Structure-Based Design.
    Lu S; He X; Ni D; Zhang J
    J Med Chem; 2019 Jul; 62(14):6405-6421. PubMed ID: 30817889
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Harnessing allostery: a novel approach to drug discovery.
    Lu S; Li S; Zhang J
    Med Res Rev; 2014 Nov; 34(6):1242-85. PubMed ID: 24827416
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Allosteric Modulators of Protein-Protein Interactions (PPIs).
    Ni D; Liu N; Sheng C
    Adv Exp Med Biol; 2019; 1163():313-334. PubMed ID: 31707709
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The design of covalent allosteric drugs.
    Nussinov R; Tsai CJ
    Annu Rev Pharmacol Toxicol; 2015; 55():249-67. PubMed ID: 25149918
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Emerging roles of allosteric modulators in the regulation of protein-protein interactions (PPIs): A new paradigm for PPI drug discovery.
    Ni D; Lu S; Zhang J
    Med Res Rev; 2019 Nov; 39(6):2314-2342. PubMed ID: 30957264
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Research progress of indole-fused derivatives as allosteric modulators: Opportunities for drug development.
    Luo ML; Zhao Q; He XH; Xie X; Zhu HP; You FM; Peng C; Zhan G; Huang W
    Biomed Pharmacother; 2023 Jun; 162():114574. PubMed ID: 36996677
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Strategies for the identification of allosteric modulators of G-protein-coupled receptors.
    Burford NT; Watson J; Bertekap R; Alt A
    Biochem Pharmacol; 2011 Mar; 81(6):691-702. PubMed ID: 21184747
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Screening for positive allosteric modulators of biological targets.
    Groebe DR
    Drug Discov Today; 2006 Jul; 11(13-14):632-9. PubMed ID: 16793532
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recent advances in drug discovery of GPCR allosteric modulators for neurodegenerative disorders.
    Lütjens R; Rocher JP
    Curr Opin Pharmacol; 2017 Feb; 32():91-95. PubMed ID: 28135635
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In search of negative allosteric modulators of biological targets.
    Groebe DR
    Drug Discov Today; 2009 Jan; 14(1-2):41-9. PubMed ID: 18973826
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Allosteric modulators of rhodopsin-like G protein-coupled receptors: opportunities in drug development.
    Müller CE; Schiedel AC; Baqi Y
    Pharmacol Ther; 2012 Sep; 135(3):292-315. PubMed ID: 22728155
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Allosteric modulators of α4β2 nicotinic acetylcholine receptors: a new direction for antidepressant drug discovery.
    Mantione E; Micheloni S; Alcaino C; New K; Mazzaferro S; Bermudez I
    Future Med Chem; 2012 Nov; 4(17):2217-30. PubMed ID: 23190109
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Wandering beyond small molecules: peptides as allosteric protein modulators.
    Mannes M; Martin C; Menet C; Ballet S
    Trends Pharmacol Sci; 2022 May; 43(5):406-423. PubMed ID: 34857409
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological property optimization for allosteric ligands: A medicinal chemistry perspective.
    Johnstone S; Albert JS
    Bioorg Med Chem Lett; 2017 Jun; 27(11):2239-2258. PubMed ID: 28408223
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Harnessing Reversed Allosteric Communication: A Novel Strategy for Allosteric Drug Discovery.
    Fan J; Liu Y; Kong R; Ni D; Yu Z; Lu S; Zhang J
    J Med Chem; 2021 Dec; 64(24):17728-17743. PubMed ID: 34878270
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Recent computational advances in the identification of allosteric sites in proteins.
    Lu S; Huang W; Zhang J
    Drug Discov Today; 2014 Oct; 19(10):1595-600. PubMed ID: 25107670
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Toward understanding the molecular basis for chemical allosteric modulator design.
    Wang Q; Zheng M; Huang Z; Liu X; Zhou H; Chen Y; Shi T; Zhang J
    J Mol Graph Model; 2012 Sep; 38():324-33. PubMed ID: 23085171
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Allosteric modulators of metabotropic glutamate receptors: lessons learnt from mGlu1, mGlu2 and mGlu5 potentiators and antagonists.
    Johnson MP; Nisenbaum ES; Large TH; Emkey R; Baez M; Kingston AE
    Biochem Soc Trans; 2004 Nov; 32(Pt 5):881-7. PubMed ID: 15494040
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.