BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

384 related articles for article (PubMed ID: 27895104)

  • 1. Bin1 and CD2AP polarise the endocytic generation of beta-amyloid.
    Ubelmann F; Burrinha T; Salavessa L; Gomes R; Ferreira C; Moreno N; Guimas Almeida C
    EMBO Rep; 2017 Jan; 18(1):102-122. PubMed ID: 27895104
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reduction of the expression of the late-onset Alzheimer's disease (AD) risk-factor
    Andrew RJ; De Rossi P; Nguyen P; Kowalski HR; Recupero AJ; Guerbette T; Krause SV; Rice RC; Laury-Kleintop L; Wagner SL; Thinakaran G
    J Biol Chem; 2019 Mar; 294(12):4477-4487. PubMed ID: 30692199
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CD2-associated protein (CD2AP) overexpression accelerates amyloid precursor protein (APP) transfer from early endosomes to the lysosomal degradation pathway.
    Furusawa K; Takasugi T; Chiu YW; Hori Y; Tomita T; Fukuda M; Hisanaga SI
    J Biol Chem; 2019 Jul; 294(28):10886-10899. PubMed ID: 31138646
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The neuronal-specific isoform of BIN1 regulates β-secretase cleavage of APP and Aβ generation in a RIN3-dependent manner.
    Bhattacharyya R; Teves CAF; Long A; Hofert M; Tanzi RE
    Sci Rep; 2022 Mar; 12(1):3486. PubMed ID: 35241726
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alzheimer's disease BIN1 coding variants increase intracellular Aβ levels by interfering with BACE1 recycling.
    Perdigão C; Barata MA; Burrinha T; Guimas Almeida C
    J Biol Chem; 2021 Sep; 297(3):101056. PubMed ID: 34375641
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BIN1 regulates BACE1 intracellular trafficking and amyloid-β production.
    Miyagawa T; Ebinuma I; Morohashi Y; Hori Y; Young Chang M; Hattori H; Maehara T; Yokoshima S; Fukuyama T; Tsuji S; Iwatsubo T; Prendergast GC; Tomita T
    Hum Mol Genet; 2016 Jul; 25(14):2948-2958. PubMed ID: 27179792
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
    Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
    J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BIN1 in the Pursuit of Ousting the Alzheimer's Reign: Impact on Amyloid and Tau Neuropathology.
    Kaur I; Behl T; Sundararajan G; Panneerselvam P; Vijayakumar AR; Senthilkumar GP; Venkatachalam T; Jaglan D; Yadav S; Anwer K; Fuloria NK; Sehgal A; Gulati M; Chigurupati S
    Neurotox Res; 2023 Dec; 41(6):698-707. PubMed ID: 37847429
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intracellular amyloid precursor protein sorting and amyloid-β secretion are regulated by Src-mediated phosphorylation of Mint2.
    Chaufty J; Sullivan SE; Ho A
    J Neurosci; 2012 Jul; 32(28):9613-25. PubMed ID: 22787047
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model.
    Liao F; Jiang H; Srivatsan S; Xiao Q; Lefton KB; Yamada K; Mahan TE; Lee JM; Shaw AS; Holtzman DM
    Mol Neurodegener; 2015 Mar; 10():12. PubMed ID: 25887956
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel role of RanBP9 in BACE1 processing of amyloid precursor protein and amyloid beta peptide generation.
    Lakshmana MK; Yoon IS; Chen E; Bianchi E; Koo EH; Kang DE
    J Biol Chem; 2009 May; 284(18):11863-72. PubMed ID: 19251705
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Par3 regulates polarized convergence between APP and BACE1 in hippocampal neurons.
    Sun M; Huang C; Wang H; Zhang H
    Neurobiol Aging; 2019 May; 77():87-93. PubMed ID: 30784815
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GGA1 regulates signal-dependent sorting of BACE1 to recycling endosomes, which moderates Aβ production.
    Toh WH; Chia PZC; Hossain MI; Gleeson PA
    Mol Biol Cell; 2018 Jan; 29(2):191-208. PubMed ID: 29142073
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Beta-secretase/BACE1 promotes APP endocytosis and processing in the endosomes and on cell membrane.
    Wang M; Jing T; Wang X; Yao D
    Neurosci Lett; 2018 Oct; 685():63-67. PubMed ID: 30120949
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells.
    Chen LM; Lin ZY; Zhu YG; Lin N; Zhang J; Pan XD; Chen XC
    Eur J Pharmacol; 2012 Jan; 675(1-3):15-21. PubMed ID: 22166376
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Increased expression of reticulon 3 in neurons leads to reduced axonal transport of β site amyloid precursor protein-cleaving enzyme 1.
    Deng M; He W; Tan Y; Han H; Hu X; Xia K; Zhang Z; Yan R
    J Biol Chem; 2013 Oct; 288(42):30236-30245. PubMed ID: 24005676
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer's disease.
    Sadleir KR; Kandalepas PC; Buggia-Prévot V; Nicholson DA; Thinakaran G; Vassar R
    Acta Neuropathol; 2016 Aug; 132(2):235-256. PubMed ID: 26993139
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aberrant accrual of BIN1 near Alzheimer's disease amyloid deposits in transgenic models.
    De Rossi P; Andrew RJ; Musial TF; Buggia-Prevot V; Xu G; Ponnusamy M; Ly H; Krause SV; Rice RC; de l'Estoile V; Valin T; Salem S; Despa F; Borchelt DR; Bindokas VP; Nicholson DA; Thinakaran G
    Brain Pathol; 2019 Jul; 29(4):485-501. PubMed ID: 30506549
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SPIN90 Deficiency Ameliorates Amyloid β Accumulation by Regulating APP Trafficking in AD Model Mice.
    Oh Y; Lee W; Kim SH; Lee S; Kim BC; Lee KH; Kim SH; Song WK
    Int J Mol Sci; 2022 Sep; 23(18):. PubMed ID: 36142484
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Distinct anterograde trafficking pathways of BACE1 and amyloid precursor protein from the TGN and the regulation of amyloid-β production.
    Tan JZA; Fourriere L; Wang J; Perez F; Boncompain G; Gleeson PA
    Mol Biol Cell; 2020 Jan; 31(1):27-44. PubMed ID: 31746668
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.