BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

335 related articles for article (PubMed ID: 27898698)

  • 1. Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr-/- Mice.
    Jeurissen ML; Walenbergh SM; Houben T; Hendrikx T; Li J; Oligschlaeger Y; van Gorp PJ; Gijbels MJ; Bitorina A; Nessel I; Radtke F; Vooijs M; Theys J; Shiri-Sverdlov R
    PLoS One; 2016; 11(11):e0167199. PubMed ID: 27898698
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr(-/-) mice.
    Hendrikx T; Jeurissen ML; Bieghs V; Walenbergh SM; van Gorp PJ; Verheyen F; Houben T; Guichot YD; Gijbels MJ; Leitersdorf E; Hofker MH; Lütjohann D; Shiri-Sverdlov R
    J Hepatol; 2015 Feb; 62(2):430-6. PubMed ID: 25281859
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The cholesterol derivative 27-hydroxycholesterol reduces steatohepatitis in mice.
    Bieghs V; Hendrikx T; van Gorp PJ; Verheyen F; Guichot YD; Walenbergh SM; Jeurissen ML; Gijbels M; Rensen SS; Bast A; Plat J; Kalhan SC; Koek GH; Leitersdorf E; Hofker MH; Lütjohann D; Shiri-Sverdlov R
    Gastroenterology; 2013 Jan; 144(1):167-178.e1. PubMed ID: 23041327
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling.
    Nakano T; Katsuki S; Chen M; Decano JL; Halu A; Lee LH; Pestana DVS; Kum AST; Kuromoto RK; Golden WS; Boff MS; Guimaraes GC; Higashi H; Kauffman KJ; Maejima T; Suzuki T; Iwata H; Barabási AL; Aster JC; Anderson DG; Sharma A; Singh SA; Aikawa E; Aikawa M
    Circulation; 2019 Jan; 139(1):78-96. PubMed ID: 30586693
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Macrophage Notch Ligand Delta-Like 4 Promotes Vein Graft Lesion Development: Implications for the Treatment of Vein Graft Failure.
    Koga JI; Nakano T; Dahlman JE; Figueiredo JL; Zhang H; Decano J; Khan OF; Niida T; Iwata H; Aster JC; Yagita H; Anderson DG; Ozaki CK; Aikawa M
    Arterioscler Thromb Vasc Biol; 2015 Nov; 35(11):2343-2353. PubMed ID: 26404485
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RAGE deficiency does not affect non-alcoholic steatohepatitis and atherosclerosis in Western type diet-fed Ldlr
    Bijnen M; Beelen N; Wetzels S; Gaar JV; Vroomen M; Wijnands E; Scheijen JL; van de Waarenburg MPH; Gijbels MJ; Cleutjens JP; Biessen EAL; Stehouwer CDA; Schalkwijk CG; Wouters K
    Sci Rep; 2018 Oct; 8(1):15256. PubMed ID: 30323247
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease.
    Bieghs V; Van Gorp PJ; Wouters K; Hendrikx T; Gijbels MJ; van Bilsen M; Bakker J; Binder CJ; Lütjohann D; Staels B; Hofker MH; Shiri-Sverdlov R
    PLoS One; 2012; 7(1):e30668. PubMed ID: 22295101
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis.
    Wouters K; van Gorp PJ; Bieghs V; Gijbels MJ; Duimel H; Lütjohann D; Kerksiek A; van Kruchten R; Maeda N; Staels B; van Bilsen M; Shiri-Sverdlov R; Hofker MH
    Hepatology; 2008 Aug; 48(2):474-86. PubMed ID: 18666236
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high fat-cholesterol-sugar diet model in mice.
    Ganz M; Bukong TN; Csak T; Saha B; Park JK; Ambade A; Kodys K; Szabo G
    J Transl Med; 2015 Jun; 13():193. PubMed ID: 26077675
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Myeloid-specific IRE1alpha deletion reduces tumour development in a diabetic, non-alcoholic steatohepatitis-induced hepatocellular carcinoma mouse model.
    Van Campenhout S; Tilleman L; Lefere S; Vandierendonck A; Raevens S; Verhelst X; Geerts A; Van Nieuwerburgh F; Van Vlierberghe H; Devisscher L
    Metabolism; 2020 Jun; 107():154220. PubMed ID: 32243868
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis.
    Bashiri A; Nesan D; Tavallaee G; Sue-Chue-Lam I; Chien K; Maguire GF; Naples M; Zhang J; Magomedova L; Adeli K; Cummins CL; Ng DS
    Biochim Biophys Acta; 2016 Jul; 1861(7):594-605. PubMed ID: 27090939
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CD44 is a key player in non-alcoholic steatohepatitis.
    Patouraux S; Rousseau D; Bonnafous S; Lebeaupin C; Luci C; Canivet CM; Schneck AS; Bertola A; Saint-Paul MC; Iannelli A; Gugenheim J; Anty R; Tran A; Bailly-Maitre B; Gual P
    J Hepatol; 2017 Aug; 67(2):328-338. PubMed ID: 28323124
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells.
    Bieghs V; Verheyen F; van Gorp PJ; Hendrikx T; Wouters K; Lütjohann D; Gijbels MJ; Febbraio M; Binder CJ; Hofker MH; Shiri-Sverdlov R
    PLoS One; 2012; 7(3):e34378. PubMed ID: 22470565
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice.
    Hendrikx T; Bieghs V; Walenbergh SM; van Gorp PJ; Verheyen F; Jeurissen ML; Steinbusch MM; Vaes N; Binder CJ; Koek GH; Stienstra R; Netea MG; Hofker MH; Shiri-Sverdlov R
    PLoS One; 2013; 8(12):e78792. PubMed ID: 24312444
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Myeloid cells in liver and bone marrow acquire a functionally distinct inflammatory phenotype during obesity-related steatohepatitis.
    Krenkel O; Hundertmark J; Abdallah AT; Kohlhepp M; Puengel T; Roth T; Branco DPP; Mossanen JC; Luedde T; Trautwein C; Costa IG; Tacke F
    Gut; 2020 Mar; 69(3):551-563. PubMed ID: 31076404
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TLR9 is up-regulated in human and murine NASH: pivotal role in inflammatory recruitment and cell survival.
    Mridha AR; Haczeyni F; Yeh MM; Haigh WG; Ioannou GN; Barn V; Ajamieh H; Adams L; Hamdorf JM; Teoh NC; Farrell GC
    Clin Sci (Lond); 2017 Aug; 131(16):2145-2159. PubMed ID: 28687713
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IFN-γ deficiency attenuates hepatic inflammation and fibrosis in a steatohepatitis model induced by a methionine- and choline-deficient high-fat diet.
    Luo XY; Takahara T; Kawai K; Fujino M; Sugiyama T; Tsuneyama K; Tsukada K; Nakae S; Zhong L; Li XK
    Am J Physiol Gastrointest Liver Physiol; 2013 Dec; 305(12):G891-9. PubMed ID: 24136786
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.
    Fukuda D; Aikawa E; Swirski FK; Novobrantseva TI; Kotelianski V; Gorgun CZ; Chudnovskiy A; Yamazaki H; Croce K; Weissleder R; Aster JC; Hotamisligil GS; Yagita H; Aikawa M
    Proc Natl Acad Sci U S A; 2012 Jul; 109(27):E1868-77. PubMed ID: 22699504
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neutrophil-derived myeloperoxidase aggravates non-alcoholic steatohepatitis in low-density lipoprotein receptor-deficient mice.
    Rensen SS; Bieghs V; Xanthoulea S; Arfianti E; Bakker JA; Shiri-Sverdlov R; Hofker MH; Greve JW; Buurman WA
    PLoS One; 2012; 7(12):e52411. PubMed ID: 23285030
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deleting myeloid IL-10 receptor signalling attenuates atherosclerosis in LDLR-/- mice by altering intestinal cholesterol fluxes.
    Stöger JL; Boshuizen MC; Brufau G; Gijbels MJ; Wolfs IM; van der Velden S; Pöttgens CC; Vergouwe MN; Wijnands E; Beckers L; Goossens P; Kerksiek A; Havinga R; Müller W; Lütjohann D; Groen AK; de Winther MP
    Thromb Haemost; 2016 Aug; 116(3):565-77. PubMed ID: 27358035
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.