BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 27909940)

  • 21. [Effect of casamino acid on intergeneric conjugation in rapamycin-producing Streptomyces hygroscopicus ATCC29253].
    Zhang W; Lu H; He J
    Wei Sheng Wu Xue Bao; 2012 Feb; 52(2):198-205. PubMed ID: 22586998
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Improved PKS Gene Expression With Strong Endogenous Promoter Resulted in Geldanamycin Yield Increase.
    Wang X; Ning X; Zhao Q; Kang Q; Bai L
    Biotechnol J; 2017 Nov; 12(11):. PubMed ID: 28731630
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Production of a novel FK520 analog in Streptomyces hygroscopicus: improving titer while minimizing impurities.
    Regentin R; Cadapan L; Ou S; Zavala S; Licari P
    J Ind Microbiol Biotechnol; 2002 Jan; 28(1):12-6. PubMed ID: 11938465
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Characterization of negative regulatory genes for the biosynthesis of rapamycin in Streptomyces rapamycinicus and its application for improved production.
    Yoo YJ; Hwang JY; Shin HL; Cui H; Lee J; Yoon YJ
    J Ind Microbiol Biotechnol; 2015 Jan; 42(1):125-35. PubMed ID: 25424695
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Biosynthesis of rapamycin and its regulation: past achievements and recent progress.
    Park SR; Yoo YJ; Ban YH; Yoon YJ
    J Antibiot (Tokyo); 2010 Aug; 63(8):434-41. PubMed ID: 20588302
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Production of rapamycin in Streptomyces hygroscopicus from glycerol-based media optimized by systemic methodology.
    Kim YH; Park BS; Bhatia SK; Seo HM; Jeon JM; Kim HJ; Yi DH; Lee JH; Choi KY; Park HY; Kim YG; Yang YH
    J Microbiol Biotechnol; 2014 Oct; 24(10):1319-26. PubMed ID: 25001557
    [TBL] [Abstract][Full Text] [Related]  

  • 27. An Efficient Method To Generate Gene Deletion Mutants of the Rapamycin-Producing Bacterium Streptomyces iranensis HM 35.
    Netzker T; Schroeckh V; Gregory MA; Flak M; Krespach MKC; Leadlay PF; Brakhage AA
    Appl Environ Microbiol; 2016 Jun; 82(12):3481-3492. PubMed ID: 27037115
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Isolation and characterization of pre-rapamycin, the first macrocyclic intermediate in the biosynthesis of the immunosuppressant rapamycin by S. hygroscopicus.
    Gregory MA; Gaisser S; Lill RE; Hong H; Sheridan RM; Wilkinson B; Petkovic H; Weston AJ; Carletti I; Lee HL; Staunton J; Leadlay PF
    Angew Chem Int Ed Engl; 2004 May; 43(19):2551-3. PubMed ID: 15127450
    [No Abstract]   [Full Text] [Related]  

  • 29. Engineering of the LysR family transcriptional regulator FkbR1 and its target gene to improve ascomycin production.
    Song K; Wei L; Liu J; Wang J; Qi H; Wen J
    Appl Microbiol Biotechnol; 2017 Jun; 101(11):4581-4592. PubMed ID: 28349163
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Inactivation of putative PKS genes can double geldanamycin yield in Streptomyces hygroscopicus 17997.
    Li YH; Li M; He WQ; Wang YG; Shao RG
    Genet Mol Res; 2013 Jun; 12(2):2076-85. PubMed ID: 23913387
    [TBL] [Abstract][Full Text] [Related]  

  • 31. [Establishment of gene transduction system in geldanamycin producer - Streptomyces hygroscopicus 17997 and its application for gene disruption experiment].
    Gao HY; Wang YG; Gao QJ; Shang GD; Sun GZ; Yang Y
    Sheng Wu Gong Cheng Xue Bao; 2003 Jul; 19(4):407-11. PubMed ID: 15969055
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Mutational biosynthesis of tacrolimus analogues by fkbO deletion mutant of Streptomyces sp. KCTC 11604BP.
    Kim DH; Ryu JH; Lee KS; Lee BM; Lee MO; Lim SK; Maeng PJ
    Appl Microbiol Biotechnol; 2013 Jul; 97(13):5881-92. PubMed ID: 23392766
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Enhancement of FK506 production by engineering secondary pathways of Streptomyces tsukubaensis and exogenous feeding strategies.
    Huang D; Xia M; Li S; Wen J; Jia X
    J Ind Microbiol Biotechnol; 2013 Sep; 40(9):1023-37. PubMed ID: 23779221
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Approaches towards the enhanced production of Rapamycin by Streptomyces hygroscopicus MTCC 4003 through mutagenesis and optimization of process parameters by Taguchi orthogonal array methodology.
    Dutta S; Basak B; Bhunia B; Sinha A; Dey A
    World J Microbiol Biotechnol; 2017 May; 33(5):90. PubMed ID: 28390015
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Analysis of metabolic networks of Streptomyces leeuwenhoekii C34 by means of a genome scale model: Prediction of modifications that enhance the production of specialized metabolites.
    Razmilic V; Castro JF; Andrews B; Asenjo JA
    Biotechnol Bioeng; 2018 Jul; 115(7):1815-1828. PubMed ID: 29578590
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Metabolic engineering of
    He M; Wen J; Yin Y; Wang P
    3 Biotech; 2021 Oct; 11(10):448. PubMed ID: 34631349
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Mutagenesis of the rapamycin producer Streptomyces hygroscopicus FC904.
    Cheng YR; Huang J; Qiang H; Lin WL; Demain AL
    J Antibiot (Tokyo); 2001 Nov; 54(11):967-72. PubMed ID: 11827040
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Deletion of rapQONML from the rapamycin gene cluster of Streptomyces hygroscopicus gives production of the 16-O-desmethyl-27-desmethoxy analog.
    Chung L; Liu L; Patel S; Carney JR; Reeves CD
    J Antibiot (Tokyo); 2001 Mar; 54(3):250-6. PubMed ID: 11372782
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Production of novel rapamycin analogs by precursor-directed biosynthesis.
    Ritacco FV; Graziani EI; Summers MY; Zabriskie TM; Yu K; Bernan VS; Carter GT; Greenstein M
    Appl Environ Microbiol; 2005 Apr; 71(4):1971-6. PubMed ID: 15812028
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Developing an endogenous quorum-sensing based CRISPRi circuit for autonomous and tunable dynamic regulation of multiple targets in Streptomyces.
    Tian J; Yang G; Gu Y; Sun X; Lu Y; Jiang W
    Nucleic Acids Res; 2020 Aug; 48(14):8188-8202. PubMed ID: 32672817
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.