BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 27913676)

  • 1. Translational control by mTOR-independent routes: how eIF6 organizes metabolism.
    Miluzio A; Ricciardi S; Manfrini N; Alfieri R; Oliveto S; Brina D; Biffo S
    Biochem Soc Trans; 2016 Dec; 44(6):1667-1673. PubMed ID: 27913676
    [TBL] [Abstract][Full Text] [Related]  

  • 2. eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription.
    Brina D; Miluzio A; Ricciardi S; Clarke K; Davidsen PK; Viero G; Tebaldi T; Offenhäuser N; Rozman J; Rathkolb B; Neschen S; Klingenspor M; Wolf E; Gailus-Durner V; Fuchs H; Hrabe de Angelis M; Quattrone A; Falciani F; Biffo S
    Nat Commun; 2015 Sep; 6():8261. PubMed ID: 26383020
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma.
    Scagliola A; Miluzio A; Ventura G; Oliveto S; Cordiglieri C; Manfrini N; Cirino D; Ricciardi S; Valenti L; Baselli G; D'Ambrosio R; Maggioni M; Brina D; Bresciani A; Biffo S
    Nat Commun; 2021 Aug; 12(1):4878. PubMed ID: 34385447
    [TBL] [Abstract][Full Text] [Related]  

  • 4. eIF6 anti-association activity is required for ribosome biogenesis, translational control and tumor progression.
    Brina D; Miluzio A; Ricciardi S; Biffo S
    Biochim Biophys Acta; 2015 Jul; 1849(7):830-5. PubMed ID: 25252159
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crosstalks between translation and metabolism in cancer.
    Biffo S; Manfrini N; Ricciardi S
    Curr Opin Genet Dev; 2018 Feb; 48():75-81. PubMed ID: 29153483
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation.
    Gandin V; Miluzio A; Barbieri AM; Beugnet A; Kiyokawa H; Marchisio PC; Biffo S
    Nature; 2008 Oct; 455(7213):684-8. PubMed ID: 18784653
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modulating eIF6 levels unveils the role of translation in ecdysone biosynthesis during Drosophila development.
    Russo A; Gatti G; Alfieri R; Pesce E; Soanes K; Ricciardi S; Mancino M; Cheroni C; Vaccari T; Biffo S; Calamita P
    Dev Biol; 2019 Nov; 455(1):100-111. PubMed ID: 31283922
    [TBL] [Abstract][Full Text] [Related]  

  • 8.
    Krishnamoorthy GP; Davidson NR; Leach SD; Zhao Z; Lowe SW; Lee G; Landa I; Nagarajah J; Saqcena M; Singh K; Wendel HG; Dogan S; Tamarapu PP; Blenis J; Ghossein RA; Knauf JA; Rätsch G; Fagin JA
    Cancer Discov; 2019 Feb; 9(2):264-281. PubMed ID: 30305285
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Eukaryotic initiation factor 6 mediates a continuum between 60S ribosome biogenesis and translation.
    Miluzio A; Beugnet A; Volta V; Biffo S
    EMBO Rep; 2009 May; 10(5):459-65. PubMed ID: 19373251
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturation.
    Ricciardi S; Miluzio A; Brina D; Clarke K; Bonomo M; Aiolfi R; Guidotti LG; Falciani F; Biffo S
    J Thromb Haemost; 2015 Nov; 13(11):2108-18. PubMed ID: 26391622
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery and Preliminary Characterization of Translational Modulators that Impair the Binding of eIF6 to 60S Ribosomal Subunits.
    Pesce E; Miluzio A; Turcano L; Minici C; Cirino D; Calamita P; Manfrini N; Oliveto S; Ricciardi S; Grifantini R; Degano M; Bresciani A; Biffo S
    Cells; 2020 Jan; 9(1):. PubMed ID: 31936702
    [TBL] [Abstract][Full Text] [Related]  

  • 12. c-Myc and eIF4F are components of a feedforward loop that links transcription and translation.
    Lin CJ; Cencic R; Mills JR; Robert F; Pelletier J
    Cancer Res; 2008 Jul; 68(13):5326-34. PubMed ID: 18593934
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MYC and metabolism on the path to cancer.
    Hsieh AL; Walton ZE; Altman BJ; Stine ZE; Dang CV
    Semin Cell Dev Biol; 2015 Jul; 43():11-21. PubMed ID: 26277543
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SLC1A5 glutamine transporter is a target of MYC and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice.
    Zhao X; Petrashen AP; Sanders JA; Peterson AL; Sedivy JM
    Aging Cell; 2019 Jun; 18(3):e12947. PubMed ID: 30909319
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4
    Manfrini N; Ricciardi S; Miluzio A; Fedeli M; Scagliola A; Gallo S; Brina D; Adler T; Busch DH; Gailus-Durner V; Fuchs H; Hrabě de Angelis M; Biffo S
    Dev Comp Immunol; 2017 Dec; 77():69-76. PubMed ID: 28743432
    [TBL] [Abstract][Full Text] [Related]  

  • 16. eIF6 promotes the malignant progression of human hepatocellular carcinoma via the mTOR signaling pathway.
    Sun L; Liu S; Wang X; Zheng X; Chen Y; Shen H
    J Transl Med; 2021 May; 19(1):216. PubMed ID: 34016142
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Impairment of cytoplasmic eIF6 activity restricts lymphomagenesis and tumor progression without affecting normal growth.
    Miluzio A; Beugnet A; Grosso S; Brina D; Mancino M; Campaner S; Amati B; de Marco A; Biffo S
    Cancer Cell; 2011 Jun; 19(6):765-75. PubMed ID: 21665150
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression.
    Tameire F; Verginadis II; Leli NM; Polte C; Conn CS; Ojha R; Salas Salinas C; Chinga F; Monroy AM; Fu W; Wang P; Kossenkov A; Ye J; Amaravadi RK; Ignatova Z; Fuchs SY; Diehl JA; Ruggero D; Koumenis C
    Nat Cell Biol; 2019 Jul; 21(7):889-899. PubMed ID: 31263264
    [TBL] [Abstract][Full Text] [Related]  

  • 19. α-Solanine induces ROS-mediated autophagy through activation of endoplasmic reticulum stress and inhibition of Akt/mTOR pathway.
    Hasanain M; Bhattacharjee A; Pandey P; Ashraf R; Singh N; Sharma S; Vishwakarma AL; Datta D; Mitra K; Sarkar J
    Cell Death Dis; 2015 Aug; 6(8):e1860. PubMed ID: 26313911
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of the eukaryotic initiation factor 6 and kermit2/gipc2 in Xenopus laevis pronephros formation.
    Tussellino M; De Marco N; Campanella C; Carotenuto R
    Int J Dev Biol; 2012; 56(5):357-62. PubMed ID: 22689378
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.