These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 27915383)

  • 1. A covalent antagonist for the human adenosine A
    Yang X; Dong G; Michiels TJM; Lenselink EB; Heitman L; Louvel J; IJzerman AP
    Purinergic Signal; 2017 Jun; 13(2):191-201. PubMed ID: 27915383
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Binding kinetics of ZM241385 derivatives at the human adenosine A2A receptor.
    Guo D; Xia L; van Veldhoven JP; Hazeu M; Mocking T; Brussee J; Ijzerman AP; Heitman LH
    ChemMedChem; 2014 Apr; 9(4):752-61. PubMed ID: 24591302
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An Fc-Small Molecule Conjugate for Targeted Inhibition of the Adenosine 2A Receptor.
    Hsiao PY; Kalin JH; Sun IH; Amin MN; Lo YC; Chiang MJ; Giddens J; Sysa-Shah P; Gabrielson K; Wang LX; Powell JD; Cole PA
    Chembiochem; 2016 Oct; 17(20):1951-1960. PubMed ID: 27432157
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 125I-4-(2-[7-amino-2-[2-furyl][1,2,4]triazolo[2,3-a][1,3,5] triazin-5-yl-amino]ethyl)phenol, a high affinity antagonist radioligand selective for the A2a adenosine receptor.
    Palmer TM; Poucher SM; Jacobson KA; Stiles GL
    Mol Pharmacol; 1995 Dec; 48(6):970-4. PubMed ID: 8848012
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structure of the adenosine A
    Sun B; Bachhawat P; Chu ML; Wood M; Ceska T; Sands ZA; Mercier J; Lebon F; Kobilka TS; Kobilka BK
    Proc Natl Acad Sci U S A; 2017 Feb; 114(8):2066-2071. PubMed ID: 28167788
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of novel 1,3,5-triazine as adenosine A
    Masih A; Agnihotri AK; Srivastava JK; Pandey N; Bhat HR; Singh UP
    J Biochem Mol Toxicol; 2021 Mar; 35(3):e22659. PubMed ID: 33156955
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel adenosine A(2A) receptor ligands: a synthetic, functional and computational investigation of selected literature adenosine A(2A) receptor antagonists for extending into extracellular space.
    Jörg M; Shonberg J; Mak FS; Miller ND; Yuriev E; Scammells PJ; Capuano B
    Bioorg Med Chem Lett; 2013 Jun; 23(11):3427-33. PubMed ID: 23602401
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A
    Squarcialupi L; Betti M; Catarzi D; Varano F; Falsini M; Ravani A; Pasquini S; Vincenzi F; Salmaso V; Sturlese M; Varani K; Moro S; Colotta V
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):248-263. PubMed ID: 28114825
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Revisiting a receptor-based pharmacophore hypothesis for human A(2A) adenosine receptor antagonists.
    Bacilieri M; Ciancetta A; Paoletta S; Federico S; Cosconati S; Cacciari B; Taliani S; Da Settimo F; Novellino E; Klotz KN; Spalluto G; Moro S
    J Chem Inf Model; 2013 Jul; 53(7):1620-37. PubMed ID: 23705857
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives. Evaluation of different moieties on the 6-aryl ring to obtain potent and selective human A
    Falsini M; Ceni C; Catarzi D; Varano F; Dal Ben D; Marucci G; Buccioni M; Martí Navia A; Volpini R; Colotta V
    Bioorg Med Chem Lett; 2020 Jun; 30(11):127126. PubMed ID: 32241719
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular Basis of Ligand Dissociation from the Adenosine A2A Receptor.
    Guo D; Pan AC; Dror RO; Mocking T; Liu R; Heitman LH; Shaw DE; IJzerman AP
    Mol Pharmacol; 2016 May; 89(5):485-91. PubMed ID: 26873858
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Validation of a Na
    Noël F; do Monte FM
    J Pharmacol Toxicol Methods; 2017; 84():51-56. PubMed ID: 27810394
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 5'-Substituted Amiloride Derivatives as Allosteric Modulators Binding in the Sodium Ion Pocket of the Adenosine A2A Receptor.
    Massink A; Louvel J; Adlere I; van Veen C; Huisman BJ; Dijksteel GS; Guo D; Lenselink EB; Buckley BJ; Matthews H; Ranson M; Kelso M; IJzerman AP
    J Med Chem; 2016 May; 59(10):4769-77. PubMed ID: 27124340
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of the potency, selectivity, and pharmacokinetic profile for six adenosine A2A receptor antagonists.
    Yang M; Soohoo D; Soelaiman S; Kalla R; Zablocki J; Chu N; Leung K; Yao L; Diamond I; Belardinelli L; Shryock JC
    Naunyn Schmiedebergs Arch Pharmacol; 2007 Apr; 375(2):133-44. PubMed ID: 17310264
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of 1,2,4-triazine derivatives as adenosine A(2A) antagonists using structure based drug design.
    Congreve M; Andrews SP; Doré AS; Hollenstein K; Hurrell E; Langmead CJ; Mason JS; Ng IW; Tehan B; Zhukov A; Weir M; Marshall FH
    J Med Chem; 2012 Mar; 55(5):1898-903. PubMed ID: 22220592
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A
    Falsini M; Squarcialupi L; Catarzi D; Varano F; Betti M; Dal Ben D; Marucci G; Buccioni M; Volpini R; De Vita T; Cavalli A; Colotta V
    J Med Chem; 2017 Jul; 60(13):5772-5790. PubMed ID: 28590753
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Piperazine derivatives of [1,2,4]triazolo[1,5-a][1,3,5]triazine as potent and selective adenosine A2a receptor antagonists.
    Vu CB; Peng B; Kumaravel G; Smits G; Jin X; Phadke D; Engber T; Huang C; Reilly J; Tam S; Grant D; Hetu G; Chen L; Zhang J; Petter RC
    J Med Chem; 2004 Aug; 47(17):4291-9. PubMed ID: 15294001
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ligand binding and subtype selectivity of the human A(2A) adenosine receptor: identification and characterization of essential amino acid residues.
    Jaakola VP; Lane JR; Lin JY; Katritch V; Ijzerman AP; Stevens RC
    J Biol Chem; 2010 Apr; 285(17):13032-44. PubMed ID: 20147292
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist.
    Jaakola VP; Griffith MT; Hanson MA; Cherezov V; Chien EY; Lane JR; Ijzerman AP; Stevens RC
    Science; 2008 Nov; 322(5905):1211-7. PubMed ID: 18832607
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and SAR studies of analogues of 4-(3,3-dimethyl-butyrylamino)-3,5-difluoro-N-thiazol-2-yl-benzamide (Lu AA41063) as adenosine A2A receptor ligands with improved aqueous solubility.
    Mikkelsen GK; Langgård M; Schrøder TJ; Kreilgaard M; Jørgensen EB; Brandt G; Griffon Y; Boffey R; Bang-Andersen B
    Bioorg Med Chem Lett; 2015 Mar; 25(6):1212-6. PubMed ID: 25701253
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.