BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 27923619)

  • 1. Synthesis and application of β-carbolines as novel multi-functional anti-Alzheimer's disease agents.
    Horton W; Sood A; Peerannawar S; Kugyela N; Kulkarni A; Tulsan R; Tran CD; Soule J; LeVine H; Török B; Török M
    Bioorg Med Chem Lett; 2017 Jan; 27(2):232-236. PubMed ID: 27923619
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Lan JS; Xie SS; Li SY; Pan LF; Wang XB; Kong LY
    Bioorg Med Chem; 2014 Nov; 22(21):6089-104. PubMed ID: 25282654
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pterostilbene-O-acetamidoalkylbenzylamines derivatives as novel dual inhibitors of cholinesterase with anti-β-amyloid aggregation and antioxidant properties for the treatment of Alzheimer's disease.
    Li Y; Qiang X; Li Y; Yang X; Luo L; Xiao G; Cao Z; Tan Z; Deng Y
    Bioorg Med Chem Lett; 2016 Apr; 26(8):2035-9. PubMed ID: 26947607
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and evaluation of novel bivalent β-carboline derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    Zhao Y; Ye F; Xu J; Liao Q; Chen L; Zhang W; Sun H; Liu W; Feng F; Qu W
    Bioorg Med Chem; 2018 Jul; 26(13):3812-3824. PubMed ID: 29960728
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer's disease.
    Wichur T; Więckowska A; Więckowski K; Godyń J; Jończyk J; Valdivieso ÁDR; Panek D; Pasieka A; Sabaté R; Knez D; Gobec S; Malawska B
    Eur J Med Chem; 2020 Feb; 187():111916. PubMed ID: 31812794
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of indanone derivatives as multi-target-directed ligands against Alzheimer's disease.
    Huang L; Miao H; Sun Y; Meng F; Li X
    Eur J Med Chem; 2014 Nov; 87():429-39. PubMed ID: 25282266
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Multifunctional tacrine-flavonoid hybrids with cholinergic, β-amyloid-reducing, and metal chelating properties for the treatment of Alzheimer's disease.
    Li SY; Wang XB; Xie SS; Jiang N; Wang KD; Yao HQ; Sun HB; Kong LY
    Eur J Med Chem; 2013 Nov; 69():632-46. PubMed ID: 24095756
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives.
    Chakravarty H; Ju Y; Chen WH; Tam KY
    Drug Dev Res; 2020 Apr; 81(2):242-255. PubMed ID: 31837041
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and biological evaluation of novel (4-(1,2,4-oxadiazol-5-yl)phenyl)-2-aminoacetamide derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    Liu T; Chen S; Du J; Xing S; Li R; Li Z
    Eur J Med Chem; 2022 Jan; 227():113973. PubMed ID: 34752955
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and evaluation of novel cinnamic acid derivatives bearing N-benzyl pyridinium moiety as multifunctional cholinesterase inhibitors for Alzheimer's disease.
    Lan JS; Hou JW; Liu Y; Ding Y; Zhang Y; Li L; Zhang T
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):776-788. PubMed ID: 28585866
    [TBL] [Abstract][Full Text] [Related]  

  • 11. New multifunctional melatonin-derived benzylpyridinium bromides with potent cholinergic, antioxidant, and neuroprotective properties as innovative drugs for Alzheimer's disease.
    Luo XT; Wang CM; Liu Y; Huang ZG
    Eur J Med Chem; 2015 Oct; 103():302-11. PubMed ID: 26363866
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and evaluation of novel multi-target-directed ligands for treatment of Alzheimer's disease based on coumarin and lipoic acid scaffolds.
    Jalili-Baleh L; Forootanfar H; Küçükkılınç TT; Nadri H; Abdolahi Z; Ameri A; Jafari M; Ayazgok B; Baeeri M; Rahimifard M; Abbas Bukhari SN; Abdollahi M; Ganjali MR; Emami S; Khoobi M; Foroumadi A
    Eur J Med Chem; 2018 May; 152():600-614. PubMed ID: 29763808
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
    Zhu J; Yang H; Chen Y; Lin H; Li Q; Mo J; Bian Y; Pei Y; Sun H
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):496-506. PubMed ID: 29405075
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tacrine-hydroxamate derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation.
    Xu A; He F; Zhang X; Li X; Ran Y; Wei C; James Chou C; Zhang R; Wu J
    Bioorg Chem; 2020 May; 98():103721. PubMed ID: 32193030
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and evaluation of scutellarein-O-alkylamines as multifunctional agents for the treatment of Alzheimer's disease.
    Sang Z; Qiang X; Li Y; Yuan W; Liu Q; Shi Y; Ang W; Luo Y; Tan Z; Deng Y
    Eur J Med Chem; 2015 Apr; 94():348-66. PubMed ID: 25778991
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and biological activity of novel tacrine-isatin Schiff base hybrid derivatives.
    Riazimontazer E; Sadeghpour H; Nadri H; Sakhteman A; Tüylü Küçükkılınç T; Miri R; Edraki N
    Bioorg Chem; 2019 Aug; 89():103006. PubMed ID: 31158577
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment.
    Makhaeva GF; Lushchekina SV; Kovaleva NV; Yu Astakhova T; Boltneva NP; Rudakova EV; Serebryakova OG; Proshin AN; Serkov IV; Trofimova TP; Tafeenko VA; Radchenko EV; Palyulin VA; Fisenko VP; Korábečný J; Soukup O; Richardson RJ
    Bioorg Chem; 2021 Jul; 112():104974. PubMed ID: 34029971
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conjugates of tacrine and 1,2,4-thiadiazole derivatives as new potential multifunctional agents for Alzheimer's disease treatment: Synthesis, quantum-chemical characterization, molecular docking, and biological evaluation.
    Makhaeva GF; Kovaleva NV; Boltneva NP; Lushchekina SV; Rudakova EV; Stupina TS; Terentiev AA; Serkov IV; Proshin AN; Radchenko EV; Palyulin VA; Bachurin SO; Richardson RJ
    Bioorg Chem; 2020 Jan; 94():103387. PubMed ID: 31735356
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interest of novel N-alkylpyridinium-indolizine hybrids in the field of Alzheimer's disease: Synthesis, characterization and evaluation of antioxidant activity, cholinesterase inhibition, and amyloid fibrillation interference.
    Baussanne I; Firstova O; Dediu AB; Larosa C; Furdui B; Ghinea IO; Thomas A; Chierici S; Dinica R; Demeunynck M
    Bioorg Chem; 2021 Nov; 116():105390. PubMed ID: 34670332
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel deoxyvasicinone and tetrahydro-beta-carboline hybrids as inhibitors of acetylcholinesterase and amyloid beta aggregation.
    Du H; Jiang X; Ma M; Xu H; Liu S; Ma F
    Bioorg Med Chem Lett; 2020 Dec; 30(24):127659. PubMed ID: 33137375
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.