BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 27923831)

  • 1. Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis.
    Wahl DR; Dresser J; Wilder-Romans K; Parsels JD; Zhao SG; Davis M; Zhao L; Kachman M; Wernisch S; Burant CF; Morgan MA; Feng FY; Speers C; Lyssiotis CA; Lawrence TS
    Cancer Res; 2017 Feb; 77(4):960-970. PubMed ID: 27923831
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential activity of NADPH-producing dehydrogenases renders rodents unsuitable models to study IDH1R132 mutation effects in human glioblastoma.
    Atai NA; Renkema-Mills NA; Bosman J; Schmidt N; Rijkeboer D; Tigchelaar W; Bosch KS; Troost D; Jonker A; Bleeker FE; Miletic H; Bjerkvig R; De Witt Hamer PC; Van Noorden CJ
    J Histochem Cytochem; 2011 May; 59(5):489-503. PubMed ID: 21527585
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198.
    Molenaar RJ; Botman D; Smits MA; Hira VV; van Lith SA; Stap J; Henneman P; Khurshed M; Lenting K; Mul AN; Dimitrakopoulou D; van Drunen CM; Hoebe RA; Radivoyevitch T; Wilmink JW; Maciejewski JP; Vandertop WP; Leenders WP; Bleeker FE; van Noorden CJ
    Cancer Res; 2015 Nov; 75(22):4790-802. PubMed ID: 26363012
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Blockade of TGF-β signaling by the TGFβR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma.
    Zhang M; Kleber S; Röhrich M; Timke C; Han N; Tuettenberg J; Martin-Villalba A; Debus J; Peschke P; Wirkner U; Lahn M; Huber PE
    Cancer Res; 2011 Dec; 71(23):7155-67. PubMed ID: 22006998
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting MPS1 Enhances Radiosensitization of Human Glioblastoma by Modulating DNA Repair Proteins.
    Maachani UB; Kramp T; Hanson R; Zhao S; Celiku O; Shankavaram U; Colombo R; Caplen NJ; Camphausen K; Tandle A
    Mol Cancer Res; 2015 May; 13(5):852-62. PubMed ID: 25722303
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NADPH oxidase subunit 4 mediates cycling hypoxia-promoted radiation resistance in glioblastoma multiforme.
    Hsieh CH; Wu CP; Lee HT; Liang JA; Yu CY; Lin YJ
    Free Radic Biol Med; 2012 Aug; 53(4):649-58. PubMed ID: 22713363
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NADP+ -dependent IDH1 R132 mutation and its relevance for glioma patient survival.
    Baldewpersad Tewarie NM; Burgers IA; Dawood Y; den Boon HC; den Brok MG; Klunder JH; Koopmans KB; Rademaker E; van den Broek HB; van den Bersselaar SM; Witjes JJ; Van Noorden CJ; Atai NA
    Med Hypotheses; 2013 Jun; 80(6):728-31. PubMed ID: 23541771
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth.
    Hashizume R; Zhang A; Mueller S; Prados MD; Lulla RR; Goldman S; Saratsis AM; Mazar AP; Stegh AH; Cheng SY; Horbinski C; Haas-Kogan DA; Sarkaria JN; Waldman T; James CD
    Neuro Oncol; 2016 Nov; 18(11):1519-1528. PubMed ID: 27370397
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of a novel inactivating mutation in Isocitrate Dehydrogenase 1 (IDH1-R314C) in a high grade astrocytoma.
    van Lith SA; Navis AC; Lenting K; Verrijp K; Schepens JT; Hendriks WJ; Schubert NA; Venselaar H; Wevers RA; van Rooij A; Wesseling P; Molenaar RJ; van Noorden CJ; Pusch S; Tops B; Leenders WP
    Sci Rep; 2016 Jul; 6():30486. PubMed ID: 27460417
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Increased cure rate of glioblastoma using concurrent therapy with radiotherapy and arsenic trioxide.
    Ning S; Knox SJ
    Int J Radiat Oncol Biol Phys; 2004 Sep; 60(1):197-203. PubMed ID: 15337556
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation.
    Calvert AE; Chalastanis A; Wu Y; Hurley LA; Kouri FM; Bi Y; Kachman M; May JL; Bartom E; Hua Y; Mishra RK; Schiltz GE; Dubrovskyi O; Mazar AP; Peter ME; Zheng H; James CD; Burant CF; Chandel NS; Davuluri RV; Horbinski C; Stegh AH
    Cell Rep; 2017 May; 19(9):1858-1873. PubMed ID: 28564604
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion.
    Tateishi K; Wakimoto H; Iafrate AJ; Tanaka S; Loebel F; Lelic N; Wiederschain D; Bedel O; Deng G; Zhang B; He T; Shi X; Gerszten RE; Zhang Y; Yeh JJ; Curry WT; Zhao D; Sundaram S; Nigim F; Koerner MVA; Ho Q; Fisher DE; Roider EM; Kemeny LV; Samuels Y; Flaherty KT; Batchelor TT; Chi AS; Cahill DP
    Cancer Cell; 2015 Dec; 28(6):773-784. PubMed ID: 26678339
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Assessment of bevacizumab resistance increased by expression of BCAT1 in IDH1 wild-type glioblastoma: application of DSC perfusion MR imaging.
    Cho HR; Hong B; Kim H; Park CK; Park SH; Park S; Choi SH
    Oncotarget; 2016 Oct; 7(43):69606-69615. PubMed ID: 27626306
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IDH1
    Kim GH; Choi SY; Oh TI; Kan SY; Kang H; Lee S; Oh T; Ko HM; Lim JH
    Int J Mol Sci; 2019 May; 20(11):. PubMed ID: 31151327
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Alkylating Chemotherapeutic Temozolomide Induces Metabolic Stress in
    Tateishi K; Higuchi F; Miller JJ; Koerner MVA; Lelic N; Shankar GM; Tanaka S; Fisher DE; Batchelor TT; Iafrate AJ; Wakimoto H; Chi AS; Cahill DP
    Cancer Res; 2017 Aug; 77(15):4102-4115. PubMed ID: 28625978
    [No Abstract]   [Full Text] [Related]  

  • 16. Radiosensitivity enhancement of radioresistant glioblastoma by epidermal growth factor receptor antibody-conjugated iron-oxide nanoparticles.
    Bouras A; Kaluzova M; Hadjipanayis CG
    J Neurooncol; 2015 Aug; 124(1):13-22. PubMed ID: 25981803
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio.
    Itsumi M; Inoue S; Elia AJ; Murakami K; Sasaki M; Lind EF; Brenner D; Harris IS; Chio II; Afzal S; Cairns RA; Cescon DW; Elford AR; Ye J; Lang PA; Li WY; Wakeham A; Duncan GS; Haight J; You-Ten A; Snow B; Yamamoto K; Ohashi PS; Mak TW
    Cell Death Differ; 2015 Nov; 22(11):1837-45. PubMed ID: 25882048
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IDH mutation and MGMT promoter methylation are associated with the pseudoprogression and improved prognosis of glioblastoma multiforme patients who have undergone concurrent and adjuvant temozolomide-based chemoradiotherapy.
    Li H; Li J; Cheng G; Zhang J; Li X
    Clin Neurol Neurosurg; 2016 Dec; 151():31-36. PubMed ID: 27764705
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HDAC4 and HDAC6 sustain DNA double strand break repair and stem-like phenotype by promoting radioresistance in glioblastoma cells.
    Marampon F; Megiorni F; Camero S; Crescioli C; McDowell HP; Sferra R; Vetuschi A; Pompili S; Ventura L; De Felice F; Tombolini V; Dominici C; Maggio R; Festuccia C; Gravina GL
    Cancer Lett; 2017 Jul; 397():1-11. PubMed ID: 28342984
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Energy Metabolism in
    van Noorden CJF; Hira VVV; van Dijck AJ; Novak M; Breznik B; Molenaar RJ
    Cells; 2021 Mar; 10(3):. PubMed ID: 33810170
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.