These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 27929747)

  • 21. Current Mass Spectrometric Tools for the Bioanalyses of Therapeutic Monoclonal Antibodies and Antibody-Drug Conjugates.
    Todoroki K; Yamada T; Mizuno H; Toyo'oka T
    Anal Sci; 2018; 34(4):397-406. PubMed ID: 29643301
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life.
    Majumdar R; Esfandiary R; Bishop SM; Samra HS; Middaugh CR; Volkin DB; Weis DD
    MAbs; 2015; 7(1):84-95. PubMed ID: 25524268
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Advances in mass spectrometry-based epitope mapping of protein therapeutics.
    Liu XR; Huang RY; Zhao F; Chen G; Tao L
    J Pharm Biomed Anal; 2022 Jun; 215():114754. PubMed ID: 35427962
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Determination of thiol-to-protein ratio and drug-to-antibody ratio by in-line size exclusion chromatography with post-column reaction.
    Furuki K; Toyo'oka T
    Anal Biochem; 2017 Jun; 527():33-44. PubMed ID: 28432000
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The impact of trisulfide modification of antibodies on the properties of antibody-drug conjugates manufactured using thiol chemistry.
    Liu R; Chen X; Dushime J; Bogalhas M; Lazar AC; Ryll T; Wang L
    MAbs; 2017 Apr; 9(3):490-497. PubMed ID: 28136017
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Current ADC Linker Chemistry.
    Jain N; Smith SW; Ghone S; Tomczuk B
    Pharm Res; 2015 Nov; 32(11):3526-40. PubMed ID: 25759187
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates.
    Beck A; Terral G; Debaene F; Wagner-Rousset E; Marcoux J; Janin-Bussat MC; Colas O; Van Dorsselaer A; Cianférani S
    Expert Rev Proteomics; 2016; 13(2):157-83. PubMed ID: 26653789
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Multi-step high-throughput conjugation platform for the development of antibody-drug conjugates.
    Andris S; Wendeler M; Wang X; Hubbuch J
    J Biotechnol; 2018 Jul; 278():48-55. PubMed ID: 29733878
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Measuring the hydrogen/deuterium exchange of proteins at high spatial resolution by mass spectrometry: overcoming gas-phase hydrogen/deuterium scrambling.
    Rand KD; Zehl M; Jørgensen TJ
    Acc Chem Res; 2014 Oct; 47(10):3018-27. PubMed ID: 25171396
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Site-specific antibody-drug conjugate heterogeneity characterization and heterogeneity root cause analysis.
    Cao M; De Mel N; Jiao Y; Howard J; Parthemore C; Korman S; Thompson C; Wendeler M; Liu D
    MAbs; 2019; 11(6):1064-1076. PubMed ID: 31198090
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Evaluation of Hydrogen Exchange Mass Spectrometry as a Stability-Indicating Method for Formulation Excipient Screening for an IgG4 Monoclonal Antibody.
    Toth RT; Pace SE; Mills BJ; Joshi SB; Esfandiary R; Middaugh CR; Weis DD; Volkin DB
    J Pharm Sci; 2018 Apr; 107(4):1009-1019. PubMed ID: 29269271
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Conformational changes in oxidatively stressed monoclonal antibodies studied by hydrogen exchange mass spectrometry.
    Burkitt W; Domann P; O'Connor G
    Protein Sci; 2010 Apr; 19(4):826-35. PubMed ID: 20162626
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Quantitative collision-induced unfolding differentiates model antibody-drug conjugates.
    Tian Y; Lippens JL; Netirojjanakul C; Campuzano IDG; Ruotolo BT
    Protein Sci; 2019 Mar; 28(3):598-608. PubMed ID: 30499138
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Hydrogen-deuterium exchange mass spectrometry as an emerging analytical tool for stabilization and formulation development of therapeutic monoclonal antibodies.
    Majumdar R; Middaugh CR; Weis DD; Volkin DB
    J Pharm Sci; 2015 Feb; 104(2):327-45. PubMed ID: 25354868
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Lysine conjugation properties in human IgGs studied by integrating high-resolution native mass spectrometry and bottom-up proteomics.
    Gautier V; Boumeester AJ; Lössl P; Heck AJ
    Proteomics; 2015 Aug; 15(16):2756-65. PubMed ID: 25641908
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Online coupling of analytical hydrophobic interaction chromatography with native mass spectrometry for the characterization of monoclonal antibodies and related products.
    Yan Y; Xing T; Wang S; Daly TJ; Li N
    J Pharm Biomed Anal; 2020 Jul; 186():113313. PubMed ID: 32371326
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Conjugation Site Analysis of Lysine-Conjugated ADCs.
    Sang H; Wan N; Lu G; Tian Y; Wang G; Ye H
    Methods Mol Biol; 2020; 2078():235-250. PubMed ID: 31643061
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Isomerization and Oxidation in the Complementarity-Determining Regions of a Monoclonal Antibody: A Study of the Modification-Structure-Function Correlations by Hydrogen-Deuterium Exchange Mass Spectrometry.
    Yan Y; Wei H; Fu Y; Jusuf S; Zeng M; Ludwig R; Krystek SR; Chen G; Tao L; Das TK
    Anal Chem; 2016 Feb; 88(4):2041-50. PubMed ID: 26824491
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Mapping the Binding Interface in a Noncovalent Size Variant of a Monoclonal Antibody Using Native Mass Spectrometry, Hydrogen-Deuterium Exchange Mass Spectrometry, and Computational Analysis.
    Yan Y; Wei H; Jusuf S; Krystek SR; Chen J; Chen G; Ludwig RT; Tao L; Das TK
    J Pharm Sci; 2017 Nov; 106(11):3222-3229. PubMed ID: 28634122
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Antibody drug conjugates.
    Bakhtiar R
    Biotechnol Lett; 2016 Oct; 38(10):1655-64. PubMed ID: 27334710
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.