BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

329 related articles for article (PubMed ID: 27929752)

  • 1. Efficient production of bispecific IgG of different isotypes and species of origin in single mammalian cells.
    Dillon M; Yin Y; Zhou J; McCarty L; Ellerman D; Slaga D; Junttila TT; Han G; Sandoval W; Ovacik MA; Lin K; Hu Z; Shen A; Corn JE; Spiess C; Carter PJ
    MAbs; 2017; 9(2):213-230. PubMed ID: 27929752
    [TBL] [Abstract][Full Text] [Related]  

  • 2. "BIClonals": Production of Bispecific Antibodies in IgG Format in Transiently Transfected Mammalian Cells.
    Litvak-Greenfeld D; Vaks L; Dror S; Nahary L; Benhar I
    Methods Mol Biol; 2019; 1904():431-454. PubMed ID: 30539485
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Precise quantification of mixtures of bispecific IgG produced in single host cells by liquid chromatography-Orbitrap high-resolution mass spectrometry.
    Yin Y; Han G; Zhou J; Dillon M; McCarty L; Gavino L; Ellerman D; Spiess C; Sandoval W; Carter PJ
    MAbs; 2016; 8(8):1467-1476. PubMed ID: 27610742
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of Chain Pairing Variants of Bispecific IgG Expressed in a Single Host Cell by High-Resolution Native and Denaturing Mass Spectrometry.
    Schachner L; Han G; Dillon M; Zhou J; McCarty L; Ellerman D; Yin Y; Spiess C; Lill JR; Carter PJ; Sandoval W
    Anal Chem; 2016 Dec; 88(24):12122-12127. PubMed ID: 28193052
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Elucidating heavy/light chain pairing preferences to facilitate the assembly of bispecific IgG in single cells.
    Joshi KK; Phung W; Han G; Yin Y; Kim I; Sandoval W; Carter PJ
    MAbs; 2019 Oct; 11(7):1254-1265. PubMed ID: 31286843
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tethered-variable CL bispecific IgG: an antibody platform for rapid bispecific antibody screening.
    Kim HS; Dunshee DR; Yee A; Tong RK; Kim I; Farahi F; Hongo JA; Ernst JA; Sonoda J; Spiess C
    Protein Eng Des Sel; 2017 Sep; 30(9):627-637. PubMed ID: 28985411
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Production of bispecific antibodies in "knobs-into-holes" using a cell-free expression system.
    Xu Y; Lee J; Tran C; Heibeck TH; Wang WD; Yang J; Stafford RL; Steiner AR; Sato AK; Hallam TJ; Yin G
    MAbs; 2015; 7(1):231-42. PubMed ID: 25427258
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein design of IgG/TCR chimeras for the co-expression of Fab-like moieties within bispecific antibodies.
    Wu X; Sereno AJ; Huang F; Zhang K; Batt M; Fitchett JR; He D; Rick HL; Conner EM; Demarest SJ
    MAbs; 2015; 7(2):364-76. PubMed ID: 25611120
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nonclinical immunogenicity risk assessment for knobs-into-holes bispecific IgG
    Tsai WK; Li Y; Yin Z; Tran P; Phung Q; Zhou Z; Peng K; Qin D; Tam S; Spiess C; Brumm J; Wong M; Ye Z; Wu P; Cohen S; Carter PJ
    MAbs; 2024; 16(1):2362789. PubMed ID: 38845069
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Computational design of a specific heavy chain/κ light chain interface for expressing fully IgG bispecific antibodies.
    Froning KJ; Leaver-Fay A; Wu X; Phan S; Gao L; Huang F; Pustilnik A; Bacica M; Houlihan K; Chai Q; Fitchett JR; Hendle J; Kuhlman B; Demarest SJ
    Protein Sci; 2017 Oct; 26(10):2021-2038. PubMed ID: 28726352
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel efficient bispecific antibody format, combining a conventional antigen-binding fragment with a single domain antibody, avoids potential heavy-light chain mis-pairing.
    Huang S; Segués A; Hulsik DL; Zaiss DM; Sijts AJAM; van Duijnhoven SMJ; van Elsas A
    J Immunol Methods; 2020 Aug; 483():112811. PubMed ID: 32569598
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Efficient production of bispecific antibody by FAST-Ig
    Koga H; Yamano T; Betancur J; Nagatomo S; Ikeda Y; Yamaguchi K; Nabuchi Y; Sato K; Teranishi-Ikawa Y; Sato M; Hirayama H; Hayasaka A; Torizawa T; Haraya K; Sampei Z; Shiraiwa H; Kitazawa T; Igawa T; Kuramochi T
    MAbs; 2023; 15(1):2222441. PubMed ID: 37339067
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel CH1:CL interfaces that enhance correct light chain pairing in heterodimeric bispecific antibodies.
    Bönisch M; Sellmann C; Maresch D; Halbig C; Becker S; Toleikis L; Hock B; Rüker F
    Protein Eng Des Sel; 2017 Sep; 30(9):685-696. PubMed ID: 28981885
    [TBL] [Abstract][Full Text] [Related]  

  • 14. LUZ-Y, a novel platform for the mammalian cell production of full-length IgG-bispecific antibodies.
    Wranik BJ; Christensen EL; Schaefer G; Jackman JK; Vendel AC; Eaton D
    J Biol Chem; 2012 Dec; 287(52):43331-9. PubMed ID: 23118228
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
    Lewis SM; Wu X; Pustilnik A; Sereno A; Huang F; Rick HL; Guntas G; Leaver-Fay A; Smith EM; Ho C; Hansen-Estruch C; Chamberlain AK; Truhlar SM; Conner EM; Atwell S; Kuhlman B; Demarest SJ
    Nat Biotechnol; 2014 Feb; 32(2):191-8. PubMed ID: 24463572
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A new approach for generating bispecific antibodies based on a common light chain format and the stable architecture of human immunoglobulin G
    De Nardis C; Hendriks LJA; Poirier E; Arvinte T; Gros P; Bakker ABH; de Kruif J
    J Biol Chem; 2017 Sep; 292(35):14706-14717. PubMed ID: 28655766
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Generating bispecific human IgG1 and IgG2 antibodies from any antibody pair.
    Strop P; Ho WH; Boustany LM; Abdiche YN; Lindquist KC; Farias SE; Rickert M; Appah CT; Pascua E; Radcliffe T; Sutton J; Chaparro-Riggers J; Chen W; Casas MG; Chin SM; Wong OK; Liu SH; Vergara G; Shelton D; Rajpal A; Pons J
    J Mol Biol; 2012 Jul; 420(3):204-19. PubMed ID: 22543237
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Efficient generation of bispecific IgG antibodies by split intein mediated protein trans-splicing system.
    Han L; Chen J; Ding K; Zong H; Xie Y; Jiang H; Zhang B; Lu H; Yin W; Gilly J; Zhu J
    Sci Rep; 2017 Aug; 7(1):8360. PubMed ID: 28827777
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies.
    Schaefer W; Regula JT; Bähner M; Schanzer J; Croasdale R; Dürr H; Gassner C; Georges G; Kettenberger H; Imhof-Jung S; Schwaiger M; Stubenrauch KG; Sustmann C; Thomas M; Scheuer W; Klein C
    Proc Natl Acad Sci U S A; 2011 Jul; 108(27):11187-92. PubMed ID: 21690412
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Engineering bispecific antibodies with defined chain pairing.
    Krah S; Sellmann C; Rhiel L; Schröter C; Dickgiesser S; Beck J; Zielonka S; Toleikis L; Hock B; Kolmar H; Becker S
    N Biotechnol; 2017 Oct; 39(Pt B):167-173. PubMed ID: 28137467
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.