147 related articles for article (PubMed ID: 27933795)
1. Potent Inhibition of 3-Deoxy-d-arabinoheptulosonate-7-phosphate (DAHP) Synthase by DAHP Oxime, a Phosphate Group Mimic.
Balachandran N; Heimhalt M; Liuni P; To F; Wilson DJ; Junop MS; Berti PJ
Biochemistry; 2016 Dec; 55(48):6617-6629. PubMed ID: 27933795
[TBL] [Abstract][Full Text] [Related]
2. Linear Free Energy Relationship Analysis of Transition State Mimicry by 3-Deoxy-d-arabino-heptulosonate-7-phosphate (DAHP) Oxime, a DAHP Synthase Inhibitor and Phosphate Mimic.
Balachandran N; To F; Berti PJ
Biochemistry; 2017 Jan; 56(4):592-601. PubMed ID: 28045507
[TBL] [Abstract][Full Text] [Related]
3. Eliminating Competition: Characterizing and Eliminating Competitive Binding at Separate Sites between DAHP Synthase's Essential Metal Ion and the Inhibitor DAHP Oxime.
Heimhalt M; Jiang S; Berti PJ
Biochemistry; 2018 Dec; 57(48):6679-6687. PubMed ID: 30398055
[TBL] [Abstract][Full Text] [Related]
4. Campylobacter jejuni KDO8P Synthase, Its Inhibition by KDO8P Oxime, and Control of the Residence Time of Slow-Binding Inhibition.
Gama SR; Balachandran N; Berti PJ
Biochemistry; 2018 Sep; 57(36):5327-5338. PubMed ID: 30125100
[TBL] [Abstract][Full Text] [Related]
5. Steady-state kinetics and inhibitor binding of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (tryptophan sensitive) from Escherichia coli.
Akowski JP; Bauerle R
Biochemistry; 1997 Dec; 36(50):15817-22. PubMed ID: 9398312
[TBL] [Abstract][Full Text] [Related]
6. Substrate and metal complexes of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Saccharomyces cerevisiae provide new insights into the catalytic mechanism.
König V; Pfeil A; Braus GH; Schneider TR
J Mol Biol; 2004 Mar; 337(3):675-90. PubMed ID: 15019786
[TBL] [Abstract][Full Text] [Related]
7. Crystal structure of phenylalanine-regulated 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Escherichia coli.
Shumilin IA; Kretsinger RH; Bauerle RH
Structure; 1999 Jul; 7(7):865-75. PubMed ID: 10425687
[TBL] [Abstract][Full Text] [Related]
8. The use of (E)- and (Z)-phosphoenol-3-fluoropyruvate as mechanistic probes reveals significant differences between the active sites of KDO8P and DAHP synthases.
Furdui CM; Sau AK; Yaniv O; Belakhov V; Woodard RW; Baasov T; Anderson KS
Biochemistry; 2005 May; 44(19):7326-35. PubMed ID: 15882071
[TBL] [Abstract][Full Text] [Related]
9. Insights into the mechanism of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (Phe) from Escherichia coli using a transient kinetic analysis.
Furdui C; Zhou L; Woodard RW; Anderson KS
J Biol Chem; 2004 Oct; 279(44):45618-25. PubMed ID: 15326172
[TBL] [Abstract][Full Text] [Related]
10. The high-resolution structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase reveals a twist in the plane of bound phosphoenolpyruvate.
Shumilin IA; Bauerle R; Kretsinger RH
Biochemistry; 2003 Apr; 42(13):3766-76. PubMed ID: 12667068
[TBL] [Abstract][Full Text] [Related]
11. An Inhibitor-in-Pieces Approach to DAHP Synthase Inhibition: Potent Enzyme and Bacterial Growth Inhibition.
Heimhalt M; Mukherjee P; Grainger RA; Szabla R; Brown C; Turner R; Junop MS; Berti PJ
ACS Infect Dis; 2021 Dec; 7(12):3292-3302. PubMed ID: 34761906
[TBL] [Abstract][Full Text] [Related]
12. Regulative fine-tuning of the two novel DAHP isoenzymes aroFp and aroGp of the filamentous fungus Aspergillus nidulans.
Hartmann M; Heinrich G; Braus GH
Arch Microbiol; 2001 Feb; 175(2):112-21. PubMed ID: 11285739
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and evaluation of dual site inhibitors of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase.
Walker SR; Jiao W; Parker EJ
Bioorg Med Chem Lett; 2011 Sep; 21(17):5092-7. PubMed ID: 21493065
[TBL] [Abstract][Full Text] [Related]
14. Substrate ambiguity and crystal structure of Pyrococcus furiosus 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase: an ancestral 3-deoxyald-2-ulosonate-phosphate synthase?
Schofield LR; Anderson BF; Patchett ML; Norris GE; Jameson GB; Parker EJ
Biochemistry; 2005 Sep; 44(36):11950-62. PubMed ID: 16142893
[TBL] [Abstract][Full Text] [Related]
15. Characterization of two 3-deoxy-d-Arabino-Heptulosonate 7-phosphate synthases from Bacillusmethanolicus.
Gruenberg M; Irla M; Myllek S; Draths K
Protein Expr Purif; 2021 Dec; 188():105972. PubMed ID: 34517109
[TBL] [Abstract][Full Text] [Related]
16. Crystal structure of the reaction complex of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Thermotoga maritima refines the catalytic mechanism and indicates a new mechanism of allosteric regulation.
Shumilin IA; Bauerle R; Wu J; Woodard RW; Kretsinger RH
J Mol Biol; 2004 Aug; 341(2):455-66. PubMed ID: 15276836
[TBL] [Abstract][Full Text] [Related]
17. Pseudomonas aeruginosa possesses two novel regulatory isozymes of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase.
Whitaker RJ; Fiske MJ; Jensen RA
J Biol Chem; 1982 Nov; 257(21):12789-94. PubMed ID: 6127340
[TBL] [Abstract][Full Text] [Related]
18. Structure of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli: comparison of the Mn(2+)*2-phosphoglycolate and the Pb(2+)*2-phosphoenolpyruvate complexes and implications for catalysis.
Wagner T; Shumilin IA; Bauerle R; Kretsinger RH
J Mol Biol; 2000 Aug; 301(2):389-99. PubMed ID: 10926516
[TBL] [Abstract][Full Text] [Related]
19. Role of Half-of-Sites Reactivity and Inter-Subunit Communications in DAHP Synthase Catalysis and Regulation.
Balachandran N; Grainger RA; Rob T; Liuni P; Wilson DJ; Junop MS; Berti PJ
Biochemistry; 2022 Oct; 61(20):2229-2240. PubMed ID: 36197914
[TBL] [Abstract][Full Text] [Related]
20. NeuNAc Oxime: A Slow-Binding and Effectively Irreversible Inhibitor of the Sialic Acid Synthase NeuB.
Popović V; Morrison E; Rosanally AZ; Balachandran N; Senson AW; Szabla R; Junop MS; Berti PJ
Biochemistry; 2019 Oct; 58(41):4236-4245. PubMed ID: 31549502
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
