245 related articles for article (PubMed ID: 27934638)
1. Comparative Evaluation of Dehydroepiandrosterone Sulfate Potential to Predict Hepatic Organic Anion Transporting Polypeptide Transporter-Based Drug-Drug Interactions.
Nishizawa K; Nakanishi T; Tamai I
Drug Metab Dispos; 2017 Feb; 45(2):224-227. PubMed ID: 27934638
[TBL] [Abstract][Full Text] [Related]
2. Dehydroepiandrosterone sulfate, a useful endogenous probe for evaluation of drug-drug interaction on hepatic organic anion transporting polypeptide (OATP) in cynomolgus monkeys.
Watanabe M; Watanabe T; Yabuki M; Tamai I
Drug Metab Pharmacokinet; 2015 Apr; 30(2):198-204. PubMed ID: 25989893
[TBL] [Abstract][Full Text] [Related]
3. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects.
Shen H; Chen W; Drexler DM; Mandlekar S; Holenarsipur VK; Shields EE; Langish R; Sidik K; Gan J; Humphreys WG; Marathe P; Lai Y
Drug Metab Dispos; 2017 Aug; 45(8):908-919. PubMed ID: 28576766
[TBL] [Abstract][Full Text] [Related]
4. Pitavastatin as an in vivo probe for studying hepatic organic anion transporting polypeptide-mediated drug-drug interactions in cynomolgus monkeys.
Takahashi T; Ohtsuka T; Yoshikawa T; Tatekawa I; Uno Y; Utoh M; Yamazaki H; Kume T
Drug Metab Dispos; 2013 Oct; 41(10):1875-82. PubMed ID: 23929936
[TBL] [Abstract][Full Text] [Related]
5. Leveraging of Rifampicin-Dosed Cynomolgus Monkeys to Identify Bile Acid 3-O-Sulfate Conjugates as Potential Novel Biomarkers for Organic Anion-Transporting Polypeptides.
Thakare R; Gao H; Kosa RE; Bi YA; Varma MVS; Cerny MA; Sharma R; Kuhn M; Huang B; Liu Y; Yu A; Walker GS; Niosi M; Tremaine L; Alnouti Y; Rodrigues AD
Drug Metab Dispos; 2017 Jul; 45(7):721-733. PubMed ID: 28396527
[TBL] [Abstract][Full Text] [Related]
6. Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver.
Vavricka SR; Van Montfoort J; Ha HR; Meier PJ; Fattinger K
Hepatology; 2002 Jul; 36(1):164-72. PubMed ID: 12085361
[TBL] [Abstract][Full Text] [Related]
7. Integrated approach of in vivo and in vitro evaluation of the involvement of hepatic uptake organic anion transporters in the drug disposition in rats using rifampicin as an inhibitor.
Imaoka T; Mikkaichi T; Abe K; Hirouchi M; Okudaira N; Izumi T
Drug Metab Dispos; 2013 Jul; 41(7):1442-9. PubMed ID: 23640987
[TBL] [Abstract][Full Text] [Related]
8. Cynomolgus monkey as a potential model to assess drug interactions involving hepatic organic anion transporting polypeptides: in vitro, in vivo, and in vitro-to-in vivo extrapolation.
Shen H; Yang Z; Mintier G; Han YH; Chen C; Balimane P; Jemal M; Zhao W; Zhang R; Kallipatti S; Selvam S; Sukrutharaj S; Krishnamurthy P; Marathe P; Rodrigues AD
J Pharmacol Exp Ther; 2013 Mar; 344(3):673-85. PubMed ID: 23297161
[TBL] [Abstract][Full Text] [Related]
9. [Development of Prediction Methods for Drug-Drug Interactions Based on the Construction of Physiologically Based Pharmacokinetic Models for Hepatic OATP Substrate Drugs and Endogenous Substrates].
Yoshikado T
Yakugaku Zasshi; 2023; 143(1):11-19. PubMed ID: 36596534
[TBL] [Abstract][Full Text] [Related]
10. Clinical significance of organic anion transporting polypeptides (OATPs) in drug disposition: their roles in hepatic clearance and intestinal absorption.
Shitara Y; Maeda K; Ikejiri K; Yoshida K; Horie T; Sugiyama Y
Biopharm Drug Dispos; 2013 Jan; 34(1):45-78. PubMed ID: 23115084
[TBL] [Abstract][Full Text] [Related]
11. Organic anion-transporting polypeptides contribute to the hepatic uptake of berberine.
Chen C; Wu ZT; Ma LL; Ni X; Lin YF; Wang L; Chen KP; Huang CG; Pan G
Xenobiotica; 2015; 45(12):1138-46. PubMed ID: 26068524
[TBL] [Abstract][Full Text] [Related]
12. Evaluation of cynomolgus monkeys for the identification of endogenous biomarkers for hepatic transporter inhibition and as a translatable model to predict pharmacokinetic interactions with statins in humans.
Chu X; Shih SJ; Shaw R; Hentze H; Chan GH; Owens K; Wang S; Cai X; Newton D; Castro-Perez J; Salituro G; Palamanda J; Fernandis A; Ng CK; Liaw A; Savage MJ; Evers R
Drug Metab Dispos; 2015 Jun; 43(6):851-63. PubMed ID: 25813937
[TBL] [Abstract][Full Text] [Related]
13. Quantitative Analyses of the Influence of Parameters Governing Rate-Determining Process of Hepatic Elimination of Drugs on the Magnitudes of Drug-Drug Interactions via Hepatic OATPs and CYP3A Using Physiologically Based Pharmacokinetic Models.
Yoshikado T; Maeda K; Kusuhara H; Furihata KI; Sugiyama Y
J Pharm Sci; 2017 Sep; 106(9):2739-2750. PubMed ID: 28495568
[TBL] [Abstract][Full Text] [Related]
14. Organic Anion-Transporting Polypeptide Genes Are Not Induced by the Pregnane X Receptor Activator Rifampin: Studies in Hepatocytes In Vitro and in Monkeys In Vivo.
Niu C; Wang Y; Zhao X; Tep S; Murakami E; Subramanian R; Smith B; Lai Y
Drug Metab Dispos; 2019 Dec; 47(12):1433-1442. PubMed ID: 31582395
[TBL] [Abstract][Full Text] [Related]
15. Induction of Human Intestinal and Hepatic Organic Anion Transporting Polypeptides: Where Is the Evidence for Its Relevance in Drug-Drug Interactions?
Rodrigues AD; Lai Y; Shen H; Varma MVS; Rowland A; Oswald S
Drug Metab Dispos; 2020 Mar; 48(3):205-216. PubMed ID: 31879282
[TBL] [Abstract][Full Text] [Related]
16. Transport Kinetics, Selective Inhibition, and Successful Prediction of In Vivo Inhibition of Rat Hepatic Organic Anion Transporting Polypeptides.
Ishida K; Ullah M; Tóth B; Juhasz V; Unadkat JD
Drug Metab Dispos; 2018 Sep; 46(9):1251-1258. PubMed ID: 29891589
[TBL] [Abstract][Full Text] [Related]
17. Transporter-Mediated Hepatic Uptake Plays an Important Role in the Pharmacokinetics and Drug-Drug Interactions of Montelukast.
Varma MV; Kimoto E; Scialis R; Bi Y; Lin J; Eng H; Kalgutkar AS; El-Kattan AF; Rodrigues AD; Tremaine LM
Clin Pharmacol Ther; 2017 Mar; 101(3):406-415. PubMed ID: 27648490
[TBL] [Abstract][Full Text] [Related]
18. Pharmacokinetics of atorvastatin and its hydroxy metabolites in rats and the effects of concomitant rifampicin single doses: relevance of first-pass effect from hepatic uptake transporters, and intestinal and hepatic metabolism.
Lau YY; Okochi H; Huang Y; Benet LZ
Drug Metab Dispos; 2006 Jul; 34(7):1175-81. PubMed ID: 16624870
[TBL] [Abstract][Full Text] [Related]
19. Evaluation of rosuvastatin as an organic anion transporting polypeptide (OATP) probe substrate: in vitro transport and in vivo disposition in cynomolgus monkeys.
Shen H; Su H; Liu T; Yao M; Mintier G; Li L; Fancher RM; Iyer R; Marathe P; Lai Y; Rodrigues AD
J Pharmacol Exp Ther; 2015 May; 353(2):380-91. PubMed ID: 25740896
[TBL] [Abstract][Full Text] [Related]
20. Quantitative Prediction of OATP-Mediated Disposition and Biliary Clearance Using Human Liver Chimeric Mice.
Miyake T; Tsutsui H; Hirabayashi M; Tachibana T
J Pharmacol Exp Ther; 2023 Nov; 387(2):135-149. PubMed ID: 37142442
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
