337 related articles for article (PubMed ID: 27934968)
1. K63-polyubiquitinated HAUSP deubiquitinates HIF-1α and dictates H3K56 acetylation promoting hypoxia-induced tumour progression.
Wu HT; Kuo YC; Hung JJ; Huang CH; Chen WY; Chou TY; Chen Y; Chen YJ; Chen YJ; Cheng WC; Teng SC; Wu KJ
Nat Commun; 2016 Dec; 7():13644. PubMed ID: 27934968
[TBL] [Abstract][Full Text] [Related]
2. Regulation of miRNA Biogenesis and Histone Modification by K63-Polyubiquitinated DDX17 Controls Cancer Stem-like Features.
Kao SH; Cheng WC; Wang YT; Wu HT; Yeh HY; Chen YJ; Tsai MH; Wu KJ
Cancer Res; 2019 May; 79(10):2549-2563. PubMed ID: 30877109
[TBL] [Abstract][Full Text] [Related]
3. Hypoxia induced E-cadherin involving regulators of Hippo pathway due to HIF-1α stabilization/nuclear translocation in bone metastasis from breast carcinoma.
Maroni P; Matteucci E; Drago L; Banfi G; Bendinelli P; Desiderio MA
Exp Cell Res; 2015 Jan; 330(2):287-299. PubMed ID: 25447306
[TBL] [Abstract][Full Text] [Related]
4. Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression.
Liu J; Zhang C; Zhao Y; Yue X; Wu H; Huang S; Chen J; Tomsky K; Xie H; Khella CA; Gatza ML; Xia D; Gao J; White E; Haffty BG; Hu W; Feng Z
Nat Commun; 2017 Nov; 8(1):1823. PubMed ID: 29180628
[TBL] [Abstract][Full Text] [Related]
5. HIF-1alpha and EPAS ubiquitination mediated by the VHL tumour suppressor involves flexibility in the ubiquitination mechanism, similar to other RING E3 ligases.
Paltoglou S; Roberts BJ
Oncogene; 2007 Jan; 26(4):604-9. PubMed ID: 16862177
[TBL] [Abstract][Full Text] [Related]
6. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
Baek JH; Mahon PC; Oh J; Kelly B; Krishnamachary B; Pearson M; Chan DA; Giaccia AJ; Semenza GL
Mol Cell; 2005 Feb; 17(4):503-12. PubMed ID: 15721254
[TBL] [Abstract][Full Text] [Related]
7. Functional regulation of hypoxia inducible factor-1α by SET9 lysine methyltransferase.
Liu Q; Geng H; Xue C; Beer TM; Qian DZ
Biochim Biophys Acta; 2015 May; 1853(5):881-91. PubMed ID: 25637186
[TBL] [Abstract][Full Text] [Related]
8. VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha.
Li Z; Wang D; Messing EM; Wu G
EMBO Rep; 2005 Apr; 6(4):373-8. PubMed ID: 15776016
[TBL] [Abstract][Full Text] [Related]
9. Role of the C-terminal alpha-helical domain of the von Hippel-Lindau protein in its E3 ubiquitin ligase activity.
Lewis MD; Roberts BJ
Oncogene; 2004 Mar; 23(13):2315-23. PubMed ID: 14691445
[TBL] [Abstract][Full Text] [Related]
10. Activation of hypoxia-induced transcription in normoxia.
Hägg M; Wennström S
Exp Cell Res; 2005 May; 306(1):180-91. PubMed ID: 15878343
[TBL] [Abstract][Full Text] [Related]
11. Prognostic implications of epithelial to mesenchymal transition related proteins (E-cadherin, Snail) and hypoxia inducible factor 1α in endometrioid endometrial carcinoma.
Abouhashem NS; Ibrahim DA; Mohamed AM
Ann Diagn Pathol; 2016 Jun; 22():1-11. PubMed ID: 27180053
[TBL] [Abstract][Full Text] [Related]
12. Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.
Nihira NT; Ogura K; Shimizu K; North BJ; Zhang J; Gao D; Inuzuka H; Wei W
Sci Signal; 2017 Feb; 10(466):. PubMed ID: 28196907
[TBL] [Abstract][Full Text] [Related]
13. Nijmegen breakage syndrome protein 1 (NBS1) modulates hypoxia inducible factor-1α (HIF-1α) stability and promotes in vitro migration and invasion under ionizing radiation.
Kuo YC; Wu HT; Hung JJ; Chou TY; Teng SC; Wu KJ
Int J Biochem Cell Biol; 2015 Jul; 64():229-38. PubMed ID: 25959252
[TBL] [Abstract][Full Text] [Related]
14. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
[TBL] [Abstract][Full Text] [Related]
15. Hsp70 and CHIP selectively mediate ubiquitination and degradation of hypoxia-inducible factor (HIF)-1alpha but Not HIF-2alpha.
Luo W; Zhong J; Chang R; Hu H; Pandey A; Semenza GL
J Biol Chem; 2010 Feb; 285(6):3651-3663. PubMed ID: 19940151
[TBL] [Abstract][Full Text] [Related]
16. The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma.
Clifford SC; Astuti D; Hooper L; Maxwell PH; Ratcliffe PJ; Maher ER
Oncogene; 2001 Aug; 20(36):5067-74. PubMed ID: 11526493
[TBL] [Abstract][Full Text] [Related]
17. HIF-1α promotes autophagic proteolysis of Dicer and enhances tumor metastasis.
Lai HH; Li JN; Wang MY; Huang HY; Croce CM; Sun HL; Lyu YJ; Kang JW; Chiu CF; Hung MC; Suzuki HI; Chen PS
J Clin Invest; 2018 Feb; 128(2):625-643. PubMed ID: 29251629
[TBL] [Abstract][Full Text] [Related]
18. Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis.
Lin CW; Wang LK; Wang SP; Chang YL; Wu YY; Chen HY; Hsiao TH; Lai WY; Lu HH; Chang YH; Yang SC; Lin MW; Chen CY; Hong TM; Yang PC
Nat Commun; 2016 Dec; 7():13867. PubMed ID: 28004751
[TBL] [Abstract][Full Text] [Related]
19. WDR5 facilitates EMT and metastasis of CCA by increasing HIF-1α accumulation in Myc-dependent and independent pathways.
Chen T; Li K; Liu Z; Liu J; Wang Y; Sun R; Li Z; Qiu B; Zhang X; Ren G; Xu Y; Zhang Z
Mol Ther; 2021 Jun; 29(6):2134-2150. PubMed ID: 33601056
[TBL] [Abstract][Full Text] [Related]
20. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
