BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1211 related articles for article (PubMed ID: 27935834)

  • 1. Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infection.
    Diner BA; Lum KK; Toettcher JE; Cristea IM
    mBio; 2016 Nov; 7(6):. PubMed ID: 27935834
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Charge-Mediated Pyrin Oligomerization Nucleates Antiviral IFI16 Sensing of Herpesvirus DNA.
    Lum KK; Howard TR; Pan C; Cristea IM
    mBio; 2019 Jul; 10(4):. PubMed ID: 31337724
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The intracellular DNA sensors cGAS and IFI16 do not mediate effective antiviral immune responses to HSV-1 in human microglial cells.
    Jeffries AM; Nitika ; Truman AW; Marriott I
    J Neurovirol; 2020 Aug; 26(4):544-555. PubMed ID: 32488842
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.
    Diner BA; Lum KK; Javitt A; Cristea IM
    Mol Cell Proteomics; 2015 Sep; 14(9):2341-56. PubMed ID: 25693804
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms of Host IFI16, PML, and Daxx Protein Restriction of Herpes Simplex Virus 1 Replication.
    Merkl PE; Orzalli MH; Knipe DM
    J Virol; 2018 May; 92(10):. PubMed ID: 29491153
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Herpes Simplex Virus 1 Abrogates the cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway via Its Virion Host Shutoff Protein, UL41.
    Su C; Zheng C
    J Virol; 2017 Mar; 91(6):. PubMed ID: 28077645
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Nuclear DNA Sensor IFI16 Indiscriminately Binds to and Diminishes Accessibility of the HSV-1 Genome to Suppress Infection.
    Howard TR; Lum KK; Kennedy MA; Cristea IM
    mSystems; 2022 Jun; 7(3):e0019822. PubMed ID: 35575489
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role for a Filamentous Nuclear Assembly of IFI16, DNA, and Host Factors in Restriction of Herpesviral Infection.
    Merkl PE; Knipe DM
    mBio; 2019 Jan; 10(1):. PubMed ID: 30670617
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PYHIN1 regulates pro-inflammatory cytokine induction rather than innate immune DNA sensing in airway epithelial cells.
    Massa D; Baran M; Bengoechea JA; Bowie AG
    J Biol Chem; 2020 Apr; 295(14):4438-4450. PubMed ID: 32102850
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Relative Contributions of the cGAS-STING and TLR3 Signaling Pathways to Attenuation of Herpes Simplex Virus 1 Replication.
    Latif MB; Raja R; Kessler PM; Sen GC
    J Virol; 2020 Feb; 94(6):. PubMed ID: 31896590
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulatory Interaction between the Cellular Restriction Factor IFI16 and Viral pp65 (pUL83) Modulates Viral Gene Expression and IFI16 Protein Stability.
    Biolatti M; Dell'Oste V; Pautasso S; von Einem J; Marschall M; Plachter B; Gariglio M; De Andrea M; Landolfo S
    J Virol; 2016 Sep; 90(18):8238-50. PubMed ID: 27384655
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Nuclear DNA Sensor IFI16 Acts as a Restriction Factor for Human Papillomavirus Replication through Epigenetic Modifications of the Viral Promoters.
    Lo Cigno I; De Andrea M; Borgogna C; Albertini S; Landini MM; Peretti A; Johnson KE; Chandran B; Landolfo S; Gariglio M
    J Virol; 2015 Aug; 89(15):7506-20. PubMed ID: 25972554
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication.
    Gariano GR; Dell'Oste V; Bronzini M; Gatti D; Luganini A; De Andrea M; Gribaudo G; Gariglio M; Landolfo S
    PLoS Pathog; 2012 Jan; 8(1):e1002498. PubMed ID: 22291595
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Restriction of Human Cytomegalovirus Replication by ISG15, a Host Effector Regulated by cGAS-STING Double-Stranded-DNA Sensing.
    Bianco C; Mohr I
    J Virol; 2017 May; 91(9):. PubMed ID: 28202760
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Porcine IFI16 Negatively Regulates cGAS Signaling Through the Restriction of DNA Binding and Stimulation.
    Zheng W; Zhou R; Li S; He S; Luo J; Zhu M; Chen N; Chen H; Meurens F; Zhu J
    Front Immunol; 2020; 11():1669. PubMed ID: 32922386
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dynamic Response of IFI16 and Promyelocytic Leukemia Nuclear Body Components to Herpes Simplex Virus 1 Infection.
    Everett RD
    J Virol; 2016 Jan; 90(1):167-79. PubMed ID: 26468536
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses.
    Dutta D; Dutta S; Veettil MV; Roy A; Ansari MA; Iqbal J; Chikoti L; Kumar B; Johnson KE; Chandran B
    PLoS Pathog; 2015 Jun; 11(6):e1005030. PubMed ID: 26121674
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human Cytomegalovirus Tegument Protein pp65 (pUL83) Dampens Type I Interferon Production by Inactivating the DNA Sensor cGAS without Affecting STING.
    Biolatti M; Dell'Oste V; Pautasso S; Gugliesi F; von Einem J; Krapp C; Jakobsen MR; Borgogna C; Gariglio M; De Andrea M; Landolfo S
    J Virol; 2018 Mar; 92(6):. PubMed ID: 29263269
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Innate nuclear sensor IFI16 translocates into the cytoplasm during the early stage of in vitro human cytomegalovirus infection and is entrapped in the egressing virions during the late stage.
    Dell'Oste V; Gatti D; Gugliesi F; De Andrea M; Bawadekar M; Lo Cigno I; Biolatti M; Vallino M; Marschall M; Gariglio M; Landolfo S
    J Virol; 2014 Jun; 88(12):6970-82. PubMed ID: 24696486
    [TBL] [Abstract][Full Text] [Related]  

  • 20. IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP.
    Jønsson KL; Laustsen A; Krapp C; Skipper KA; Thavachelvam K; Hotter D; Egedal JH; Kjolby M; Mohammadi P; Prabakaran T; Sørensen LK; Sun C; Jensen SB; Holm CK; Lebbink RJ; Johannsen M; Nyegaard M; Mikkelsen JG; Kirchhoff F; Paludan SR; Jakobsen MR
    Nat Commun; 2017 Feb; 8():14391. PubMed ID: 28186168
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 61.