These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

357 related articles for article (PubMed ID: 27936689)

  • 1. Triazole- and Tetrazole-Bridged Nucleic Acids: Synthesis, Duplex Stability, Nuclease Resistance, and in Vitro and in Vivo Antisense Potency.
    Mitsuoka Y; Yamamoto T; Kugimiya A; Waki R; Wada F; Tahara S; Sawamura M; Noda M; Fujimura Y; Kato Y; Hari Y; Obika S
    J Org Chem; 2017 Jan; 82(1):12-24. PubMed ID: 27936689
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and properties of a novel bridged nucleic acid analogue, 5'-amino-3',5'-BNA.
    Sekiguchi M; Obika S; Somjing R; Imanishi T
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(5-7):1097-100. PubMed ID: 16248099
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 2'-O,4'-C-ethylene-bridged nucleic acids (ENA): highly nuclease-resistant and thermodynamically stable oligonucleotides for antisense drug.
    Morita K; Hasegawa C; Kaneko M; Tsutsumi S; Sone J; Ishikawa T; Imanishi T; Koizumi M
    Bioorg Med Chem Lett; 2002 Jan; 12(1):73-6. PubMed ID: 11738576
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA.
    Vester B; Wengel J
    Biochemistry; 2004 Oct; 43(42):13233-41. PubMed ID: 15491130
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thioamide-Bridged Nucleic Acid (thioAmNA) Containing Thymine or 2-Thiothymine: Duplex-Forming Ability, Base Discrimination, and Enzymatic Stability.
    Habuchi T; Yamaguchi T; Obika S
    Chembiochem; 2019 Apr; 20(8):1060-1067. PubMed ID: 30552742
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) as next-generation antisense and antigene agents.
    Koizumi M
    Biol Pharm Bull; 2004 Apr; 27(4):453-6. PubMed ID: 15056846
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ENA oligonucleotides as therapeutics.
    Koizumi M
    Curr Opin Mol Ther; 2006 Apr; 8(2):144-9. PubMed ID: 16610767
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and properties of a novel bridged nucleic acid analogue bearing a P3'-->N5' phosphoroamidate linkage, 5'-amino-3', 5'-BNA.
    Sekiguchi M; Obika S; Somjing R; Imanishi T
    Nucleic Acids Symp Ser (Oxf); 2004; (48):7-8. PubMed ID: 17150451
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An overview of sugar-modified oligonucleotides for antisense therapeutics.
    Prakash TP
    Chem Biodivers; 2011 Sep; 8(9):1616-41. PubMed ID: 21922654
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and properties of a bridged nucleic acid with a perhydro-1,2-oxazin-3-one ring.
    Shrestha AR; Hari Y; Yahara A; Osawa T; Obika S
    J Org Chem; 2011 Dec; 76(24):9891-9. PubMed ID: 22059648
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fine tuning of electrostatics around the internucleotidic phosphate through incorporation of modified 2',4'-carbocyclic-LNAs and -ENAs leads to significant modulation of antisense properties.
    Zhou C; Liu Y; Andaloussi M; Badgujar N; Plashkevych O; Chattopadhyaya J
    J Org Chem; 2009 Jan; 74(1):118-34. PubMed ID: 19055352
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A bridged nucleic acid, 2',4'-BNA COC: synthesis of fully modified oligonucleotides bearing thymine, 5-methylcytosine, adenine and guanine 2',4'-BNA COC monomers and RNA-selective nucleic-acid recognition.
    Mitsuoka Y; Kodama T; Ohnishi R; Hari Y; Imanishi T; Obika S
    Nucleic Acids Res; 2009 Mar; 37(4):1225-38. PubMed ID: 19136459
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Guanidine bridged nucleic acid (GuNA): an effect of a cationic bridged nucleic acid on DNA binding affinity.
    Shrestha AR; Kotobuki Y; Hari Y; Obika S
    Chem Commun (Camb); 2014 Jan; 50(5):575-7. PubMed ID: 24270219
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pyrrolidine nucleic acids: DNA/PNA oligomers with 2-hydroxy/aminomethyl- 4-(thymin-1-yl)pyrrolidine-N-acetic acid.
    Kumar V; Pallan PS; Meena M; Ganesh KN
    Org Lett; 2001 May; 3(9):1269-72. PubMed ID: 11348211
    [TBL] [Abstract][Full Text] [Related]  

  • 15. True antisense oligonucleotides with modified nucleotides restricted in the N-conformation.
    Koizumi M
    Curr Top Med Chem; 2007; 7(7):661-5. PubMed ID: 17430207
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of ICAM-1 gene expression by antisense 2',4'-BNA oligonucleotides.
    Obika S; Hemamayi R; Masuda T; Sugimoto T; Nakagawa S; Mayumi T; Imanishi T
    Nucleic Acids Res Suppl; 2001; (1):145-6. PubMed ID: 12836306
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Locked nucleic acids: promising nucleic acid analogs for therapeutic applications.
    Veedu RN; Wengel J
    Chem Biodivers; 2010 Mar; 7(3):536-42. PubMed ID: 20232325
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of scpBNA-
    Horiba M; Yamaguchi T; Obika S
    J Org Chem; 2016 Nov; 81(22):11000-11008. PubMed ID: 27779877
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Determination of affinity constants of locked nucleic acid (LNA) and DNA duplex formation using label free sensor technology.
    Möhrle BP; Kumpf M; Gauglitz G
    Analyst; 2005 Dec; 130(12):1634-8. PubMed ID: 16284662
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and RNA binding selectivity of oligonucleotides modified with five-atom thioacetamido nucleic acid backbone structures.
    Gogoi K; Gunjal AD; Phalgune UD; Kumar VA
    Org Lett; 2007 Jul; 9(14):2697-700. PubMed ID: 17552532
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.