BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

816 related articles for article (PubMed ID: 27937122)

  • 1. Rational screening of peroxisome proliferator-activated receptor-γ agonists from natural products: potential therapeutics for heart failure.
    Chen R; Wan J; Song J; Qian Y; Liu Y; Gu S
    Pharm Biol; 2017 Dec; 55(1):503-509. PubMed ID: 27937122
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of a novel selective PPARγ ligand with partial agonist binding properties by integrated in silico/in vitro work flow.
    Kouskoumvekaki I; Petersen RK; Fratev F; Taboureau O; Nielsen TE; Oprea TI; Sonne SB; Flindt EN; Jónsdóttir SÓ; Kristiansen K
    J Chem Inf Model; 2013 Apr; 53(4):923-37. PubMed ID: 23432662
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combined QSAR-based virtual screening and fluorescence binding assay to identify natural product mediators of Interferon Regulatory Factor 7 (IRF-7) in pulmonary infection.
    Liu Y; Huang L; Ye H; Lv X
    SAR QSAR Environ Res; 2016 Nov; 27(11):967-976. PubMed ID: 27762146
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Integrated discovery of FOXO1-DNA stabilizers from marine natural products to restore chemosensitivity to anti-EGFR-based therapy for metastatic lung cancer.
    Sun Y; Ai X; Hou J; Ye X; Liu R; Shen S; Li Z; Lu S
    Mol Biosyst; 2017 Jan; 13(2):330-337. PubMed ID: 27966721
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Honokiol: a non-adipogenic PPARγ agonist from nature.
    Atanasov AG; Wang JN; Gu SP; Bu J; Kramer MP; Baumgartner L; Fakhrudin N; Ladurner A; Malainer C; Vuorinen A; Noha SM; Schwaiger S; Rollinger JM; Schuster D; Stuppner H; Dirsch VM; Heiss EH
    Biochim Biophys Acta; 2013 Oct; 1830(10):4813-9. PubMed ID: 23811337
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insights into Dynamic Mechanism of Ligand Binding to Peroxisome Proliferator-Activated Receptor γ toward Potential Pharmacological Applications.
    Miyamae Y
    Biol Pharm Bull; 2021; 44(9):1185-1195. PubMed ID: 34471046
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of PPARgamma partial agonists of natural origin (I): development of a virtual screening procedure and in vitro validation.
    Guasch L; Sala E; Castell-Auví A; Cedó L; Liedl KR; Wolber G; Muehlbacher M; Mulero M; Pinent M; Ardévol A; Valls C; Pujadas G; Garcia-Vallvé S
    PLoS One; 2012; 7(11):e50816. PubMed ID: 23226391
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review.
    Wang L; Waltenberger B; Pferschy-Wenzig EM; Blunder M; Liu X; Malainer C; Blazevic T; Schwaiger S; Rollinger JM; Heiss EH; Schuster D; Kopp B; Bauer R; Stuppner H; Dirsch VM; Atanasov AG
    Biochem Pharmacol; 2014 Nov; 92(1):73-89. PubMed ID: 25083916
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery and SAR of Natural-Product-Inspired RXR Agonists with Heterodimer Selectivity to PPARδ-RXR.
    Nakashima KI; Yamaguchi E; Noritake C; Mitsugi Y; Goto M; Hirai T; Abe N; Sakai E; Oyama M; Itoh A; Inoue M
    ACS Chem Biol; 2020 Jun; 15(6):1526-1534. PubMed ID: 32374156
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A yeast two-hybrid technology-based system for the discovery of PPARgamma agonist and antagonist.
    Chen Q; Chen J; Sun T; Shen J; Shen X; Jiang H
    Anal Biochem; 2004 Dec; 335(2):253-9. PubMed ID: 15556564
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel PPAR-gamma agonists identified from a natural product library: a virtual screening, induced-fit docking and biological assay study.
    Salam NK; Huang TH; Kota BP; Kim MS; Li Y; Hibbs DE
    Chem Biol Drug Des; 2008 Jan; 71(1):57-70. PubMed ID: 18086153
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evaluation of selected 3D virtual screening tools for the prospective identification of peroxisome proliferator-activated receptor (PPAR) γ partial agonists.
    Kaserer T; Obermoser V; Weninger A; Gust R; Schuster D
    Eur J Med Chem; 2016 Nov; 124():49-62. PubMed ID: 27560282
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PPARγ signaling and emerging opportunities for improved therapeutics.
    Wang S; Dougherty EJ; Danner RL
    Pharmacol Res; 2016 Sep; 111():76-85. PubMed ID: 27268145
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of a New Type of Covalent PPARγ Agonist using a Ligand-Linking Strategy.
    Ohtera A; Miyamae Y; Yoshida K; Maejima K; Akita T; Kakizuka A; Irie K; Masuda S; Kambe T; Nagao M
    ACS Chem Biol; 2015 Dec; 10(12):2794-804. PubMed ID: 26414848
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sulfonylthiadiazoles with an unusual binding mode as partial dual peroxisome proliferator-activated receptor (PPAR) γ/δ agonists with high potency and in vivo efficacy.
    Keil S; Matter H; Schönafinger K; Glien M; Mathieu M; Marquette JP; Michot N; Haag-Diergarten S; Urmann M; Wendler W
    ChemMedChem; 2011 Apr; 6(4):633-53. PubMed ID: 21400663
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Peroxisome Proliferator-Activated Receptor γ (PPARγ) and Ligand Choreography: Newcomers Take the Stage.
    Garcia-Vallvé S; Guasch L; Tomas-Hernández S; del Bas JM; Ollendorff V; Arola L; Pujadas G; Mulero M
    J Med Chem; 2015 Jul; 58(14):5381-94. PubMed ID: 25734377
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multi-conformation dynamic pharmacophore modeling of the peroxisome proliferator-activated receptor γ for the discovery of novel agonists.
    Sohn YS; Park C; Lee Y; Kim S; Thangapandian S; Kim Y; Kim HH; Suh JK; Lee KW
    J Mol Graph Model; 2013 Nov; 46():1-9. PubMed ID: 24104184
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, activity, and docking study of phenylthiazole acids as potential agonists of PPARγ.
    Ma L; Wang T; Shi M; Ye H
    Drug Des Devel Ther; 2016; 10():1807-15. PubMed ID: 27313447
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of PPARγ Agonists from Natural Sources Using Different In Silico Approaches.
    El-Houri RB; Mortier J; Murgueitio MS; Wolber G; Christensen LP
    Planta Med; 2015 Apr; 81(6):488-94. PubMed ID: 25251562
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of novel peroxisome proliferator-activated receptor-gamma (PPARγ) agonists using molecular modeling method.
    Gee VM; Wong FS; Ramachandran L; Sethi G; Kumar AP; Yap CW
    J Comput Aided Mol Des; 2014 Nov; 28(11):1143-51. PubMed ID: 25168706
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 41.