These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
282 related articles for article (PubMed ID: 27939202)
1. G2-checkpoint targeting and radiosensitization of HPV/p16-positive HNSCC cells through the inhibition of Chk1 and Wee1. Busch CJ; Kröger MS; Jensen J; Kriegs M; Gatzemeier F; Petersen C; Münscher A; Rothkamm K; Rieckmann T Radiother Oncol; 2017 Feb; 122(2):260-266. PubMed ID: 27939202 [TBL] [Abstract][Full Text] [Related]
2. HPV-positive HNSCC cell lines but not primary human fibroblasts are radiosensitized by the inhibition of Chk1. Busch CJ; Kriegs M; Laban S; Tribius S; Knecht R; Petersen C; Dikomey E; Rieckmann T Radiother Oncol; 2013 Sep; 108(3):495-9. PubMed ID: 23932155 [TBL] [Abstract][Full Text] [Related]
3. Targeting DNA damage response in head and neck cancers through abrogation of cell cycle checkpoints. Molkentine JM; Molkentine DP; Bridges KA; Xie T; Yang L; Sheth A; Heffernan TP; Clump DA; Faust AZ; Ferris RL; Myers JN; Frederick MJ; Mason KA; Meyn RE; Pickering CR; Skinner HD Int J Radiat Biol; 2021; 97(8):1121-1128. PubMed ID: 32073931 [TBL] [Abstract][Full Text] [Related]
4. The inhibition of PARP but not EGFR results in the radiosensitization of HPV/p16-positive HNSCC cell lines. Güster JD; Weissleder SV; Busch CJ; Kriegs M; Petersen C; Knecht R; Dikomey E; Rieckmann T Radiother Oncol; 2014 Dec; 113(3):345-51. PubMed ID: 25467050 [TBL] [Abstract][Full Text] [Related]
5. Mutations of the LIM protein AJUBA mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell-cycle inhibitors. Zhang M; Singh R; Peng S; Mazumdar T; Sambandam V; Shen L; Tong P; Li L; Kalu NN; Pickering CR; Frederick M; Myers JN; Wang J; Johnson FM Cancer Lett; 2017 Apr; 392():71-82. PubMed ID: 28126323 [TBL] [Abstract][Full Text] [Related]
6. Wee1 Kinase Inhibitor AZD1775 Radiosensitizes Hepatocellular Carcinoma Regardless of TP53 Mutational Status Through Induction of Replication Stress. Cuneo KC; Morgan MA; Davis MA; Parcels LA; Parcels J; Karnak D; Ryan C; Liu N; Maybaum J; Lawrence TS Int J Radiat Oncol Biol Phys; 2016 Jun; 95(2):782-90. PubMed ID: 26975930 [TBL] [Abstract][Full Text] [Related]
7. Dual Inhibition of PARP and the Intra-S/G2 Cell Cycle Checkpoints Results in Highly Effective Radiosensitization of HPV-Positive HNSCC Cells. Hintelmann K; Berenz T; Kriegs M; Christiansen S; Gatzemeier F; Struve N; Petersen C; Betz C; Rothkamm K; Oetting A; Rieckmann T Front Oncol; 2021; 11():683688. PubMed ID: 34354944 [TBL] [Abstract][Full Text] [Related]
8. Wee1 Kinase Inhibitor AZD1775 Effectively Sensitizes Esophageal Cancer to Radiotherapy. Yang L; Shen C; Pettit CJ; Li T; Hu AJ; Miller ED; Zhang J; Lin SH; Williams TM Clin Cancer Res; 2020 Jul; 26(14):3740-3750. PubMed ID: 32220892 [TBL] [Abstract][Full Text] [Related]
9. Chk1 and Wee1 control genotoxic-stress induced G2-M arrest in melanoma cells. Vera J; Raatz Y; Wolkenhauer O; Kottek T; Bhattacharya A; Simon JC; Kunz M Cell Signal; 2015 May; 27(5):951-60. PubMed ID: 25683911 [TBL] [Abstract][Full Text] [Related]
10. The contribution of DNA replication stress marked by high-intensity, pan-nuclear γH2AX staining to chemosensitization by CHK1 and WEE1 inhibitors. Parsels LA; Parsels JD; Tanska DM; Maybaum J; Lawrence TS; Morgan MA Cell Cycle; 2018; 17(9):1076-1086. PubMed ID: 29895190 [TBL] [Abstract][Full Text] [Related]
11. Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading. Hauge S; Naucke C; Hasvold G; Joel M; Rødland GE; Juzenas P; Stokke T; Syljuåsen RG Oncotarget; 2017 Feb; 8(7):10966-10979. PubMed ID: 28030798 [TBL] [Abstract][Full Text] [Related]
12. Combined Inhibition of Rad51 and Wee1 Enhances Cell Killing in HNSCC Through Induction of Apoptosis Associated With Excessive DNA Damage and Replication Stress. Lindemann A; Patel AA; Tang L; Tanaka N; Gleber-Netto FO; Bartels MD; Wang L; McGrail DJ; Lin SY; Frank SJ; Frederick MJ; Myers JN; Osman AA Mol Cancer Ther; 2021 Jul; 20(7):1257-1269. PubMed ID: 33947685 [TBL] [Abstract][Full Text] [Related]
13. HNSCC cell lines positive for HPV and p16 possess higher cellular radiosensitivity due to an impaired DSB repair capacity. Rieckmann T; Tribius S; Grob TJ; Meyer F; Busch CJ; Petersen C; Dikomey E; Kriegs M Radiother Oncol; 2013 May; 107(2):242-6. PubMed ID: 23602369 [TBL] [Abstract][Full Text] [Related]
14. Wee-1 Kinase Inhibition Sensitizes High-Risk HPV+ HNSCC to Apoptosis Accompanied by Downregulation of MCl-1 and XIAP Antiapoptotic Proteins. Tanaka N; Patel AA; Wang J; Frederick MJ; Kalu NN; Zhao M; Fitzgerald AL; Xie TX; Silver NL; Caulin C; Zhou G; Skinner HD; Johnson FM; Myers JN; Osman AA Clin Cancer Res; 2015 Nov; 21(21):4831-44. PubMed ID: 26124202 [TBL] [Abstract][Full Text] [Related]
15. Preclinical Evaluation of the ATR Inhibitor BAY 1895344 as a Radiosensitizer for Head and Neck Squamous Cell Carcinoma. Odhiambo DA; Pittman AN; Rickard AG; Castillo RJ; Bassil AM; Chen J; Ravotti ML; Xu ES; Himes JE; Daniel AR; Watts TL; Williams NT; Luo L; Kirsch DG; Mowery YM Int J Radiat Oncol Biol Phys; 2024 Apr; 118(5):1315-1327. PubMed ID: 38104870 [TBL] [Abstract][Full Text] [Related]
16. Differential properties of mitosis-associated events following CHK1 and WEE1 inhibitor treatments in human tongue carcinoma cells. Nojima H; Homma H; Onozato Y; Kaida A; Harada H; Miura M Exp Cell Res; 2020 Jan; 386(2):111720. PubMed ID: 31738907 [TBL] [Abstract][Full Text] [Related]
17. Impaired DNA double-strand break repair and effective radiosensitization of HPV-negative HNSCC cell lines through combined inhibition of PARP and Wee1. Oetting A; Christiansen S; Gatzemeier F; Köcher S; Bußmann L; Böttcher A; Stölzel K; Hoffmann AS; Struve N; Kriegs M; Petersen C; Betz C; Rothkamm K; Zech HB; Rieckmann T Clin Transl Radiat Oncol; 2023 Jul; 41():100630. PubMed ID: 37180052 [TBL] [Abstract][Full Text] [Related]
18. Replication Stress Leading to Apoptosis within the S-phase Contributes to Synergism between Vorinostat and AZD1775 in HNSCC Harboring High-Risk Tanaka N; Patel AA; Tang L; Silver NL; Lindemann A; Takahashi H; Jaksik R; Rao X; Kalu NN; Chen TC; Wang J; Frederick MJ; Johnson F; Gleber-Netto FO; Fu S; Kimmel M; Wang J; Hittelman WN; Pickering CR; Myers JN; Osman AA Clin Cancer Res; 2017 Nov; 23(21):6541-6554. PubMed ID: 28790110 [No Abstract] [Full Text] [Related]
19. Molecular Pathways: Targeting the Protein Kinase Wee1 in Cancer. Geenen JJJ; Schellens JHM Clin Cancer Res; 2017 Aug; 23(16):4540-4544. PubMed ID: 28442503 [TBL] [Abstract][Full Text] [Related]
20. Inhibition of WEE1 kinase and cell cycle checkpoint activation sensitizes head and neck cancers to natural killer cell therapies. Friedman J; Morisada M; Sun L; Moore EC; Padget M; Hodge JW; Schlom J; Gameiro SR; Allen CT J Immunother Cancer; 2018 Jun; 6(1):59. PubMed ID: 29925431 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]