BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 27940951)

  • 1. APOBEC3A/B-induced mutagenesis is responsible for 20% of heritable mutations in the TpCpW context.
    Seplyarskiy VB; Andrianova MA; Bazykin GA
    Genome Res; 2017 Feb; 27(2):175-184. PubMed ID: 27940951
    [TBL] [Abstract][Full Text] [Related]  

  • 2. APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication.
    Hoopes JI; Cortez LM; Mertz TM; Malc EP; Mieczkowski PA; Roberts SA
    Cell Rep; 2016 Feb; 14(6):1273-1282. PubMed ID: 26832400
    [TBL] [Abstract][Full Text] [Related]  

  • 3. APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication.
    Seplyarskiy VB; Soldatov RA; Popadin KY; Antonarakis SE; Bazykin GA; Nikolaev SI
    Genome Res; 2016 Feb; 26(2):174-82. PubMed ID: 26755635
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers.
    Chan K; Roberts SA; Klimczak LJ; Sterling JF; Saini N; Malc EP; Kim J; Kwiatkowski DJ; Fargo DC; Mieczkowski PA; Getz G; Gordenin DA
    Nat Genet; 2015 Sep; 47(9):1067-72. PubMed ID: 26258849
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Repair of base damage within break-induced replication intermediates promotes kataegis associated with chromosome rearrangements.
    Elango R; Osia B; Harcy V; Malc E; Mieczkowski PA; Roberts SA; Malkova A
    Nucleic Acids Res; 2019 Oct; 47(18):9666-9684. PubMed ID: 31392335
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Error-prone bypass of DNA lesions during lagging-strand replication is a common source of germline and cancer mutations.
    Seplyarskiy VB; Akkuratov EE; Akkuratova N; Andrianova MA; Nikolaev SI; Bazykin GA; Adameyko I; Sunyaev SR
    Nat Genet; 2019 Jan; 51(1):36-41. PubMed ID: 30510240
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Quantification of ongoing APOBEC3A activity in tumor cells by monitoring RNA editing at hotspots.
    Jalili P; Bowen D; Langenbucher A; Park S; Aguirre K; Corcoran RB; Fleischman AG; Lawrence MS; Zou L; Buisson R
    Nat Commun; 2020 Jun; 11(1):2971. PubMed ID: 32532990
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetic inhibitors of APOBEC3B-induced mutagenesis.
    Mertz TM; Rice-Reynolds E; Nguyen L; Wood A; Cordero C; Bray N; Harcy V; Vyas RK; Mitchell D; Lobachev K; Roberts SA
    Genome Res; 2023 Sep; 33(9):1568-1581. PubMed ID: 37532520
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression.
    Warren CJ; Westrich JA; Doorslaer KV; Pyeon D
    Viruses; 2017 Aug; 9(8):. PubMed ID: 28825669
    [TBL] [Abstract][Full Text] [Related]  

  • 10. APOBEC3A and APOBEC3B Activities Render Cancer Cells Susceptible to ATR Inhibition.
    Buisson R; Lawrence MS; Benes CH; Zou L
    Cancer Res; 2017 Sep; 77(17):4567-4578. PubMed ID: 28698210
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Prospectively defined patterns of APOBEC3A mutagenesis are prevalent in human cancers.
    DeWeerd RA; Németh E; Póti Á; Petryk N; Chen CL; Hyrien O; Szüts D; Green AM
    Cell Rep; 2022 Mar; 38(12):110555. PubMed ID: 35320711
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Integrative genomic analyses of APOBEC-mutational signature, expression and germline deletion of APOBEC3 genes, and immunogenicity in multiple cancer types.
    Chen Z; Wen W; Bao J; Kuhs KL; Cai Q; Long J; Shu XO; Zheng W; Guo X
    BMC Med Genomics; 2019 Sep; 12(1):131. PubMed ID: 31533728
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Monitoring APOBEC3A protein levels in human cancer cells.
    Dananberg A; Maciejowski J
    Methods Cell Biol; 2024; 182():313-327. PubMed ID: 38359985
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of human AID in yeast induces mutations in context similar to the context of somatic hypermutation at G-C pairs in immunoglobulin genes.
    Mayorov VI; Rogozin IB; Adkison LR; Frahm C; Kunkel TA; Pavlov YI
    BMC Immunol; 2005 Jun; 6():10. PubMed ID: 15949042
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Impact of functional germline variants and a deletion polymorphism in APOBEC3A and APOBEC3B on breast cancer risk and survival in a Swedish study population.
    Göhler S; Da Silva Filho MI; Johansson R; Enquist-Olsson K; Henriksson R; Hemminki K; Lenner P; Försti A
    J Cancer Res Clin Oncol; 2016 Jan; 142(1):273-6. PubMed ID: 26320772
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.
    Harjes S; Kurup HM; Rieffer AE; Bayarjargal M; Filitcheva J; Su Y; Hale TK; Filichev VV; Harjes E; Harris RS; Jameson GB
    Nat Commun; 2023 Oct; 14(1):6382. PubMed ID: 37821454
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer.
    Gansmo LB; Sofiyeva N; Bjørnslett M; Romundstad P; Hveem K; Vatten L; Dørum A; Lønning PE; Knappskog S
    Sci Rep; 2021 Dec; 11(1):23463. PubMed ID: 34873230
    [TBL] [Abstract][Full Text] [Related]  

  • 18. APOBEC3A catalyzes mutation and drives carcinogenesis in vivo.
    Law EK; Levin-Klein R; Jarvis MC; Kim H; Argyris PP; Carpenter MA; Starrett GJ; Temiz NA; Larson LK; Durfee C; Burns MB; Vogel RI; Stavrou S; Aguilera AN; Wagner S; Largaespada DA; Starr TK; Ross SR; Harris RS
    J Exp Med; 2020 Dec; 217(12):. PubMed ID: 32870257
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mitochondrial double-stranded RNA triggers induction of the antiviral DNA deaminase APOBEC3A and nuclear DNA damage.
    Wick C; Moghadasi SA; Becker JT; Fanunza E; Oh S; Bournique E; Buisson R; Harris RS
    J Biol Chem; 2023 Sep; 299(9):105073. PubMed ID: 37474103
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytidine deaminase Apobec3a induction in fallopian epithelium after exposure to follicular fluid.
    Brachova P; Alvarez NS; Van Voorhis BJ; Christenson LK
    Gynecol Oncol; 2017 Jun; 145(3):577-583. PubMed ID: 28215840
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.