265 related articles for article (PubMed ID: 27941351)
1. Anti-Cancer Effect of Cap-Translation Inhibitor 4EGI-1 in Human Glioma U87 Cells: Involvement of Mitochondrial Dysfunction and ER Stress.
Wu M; Zhang C; Li XJ; Liu Q; Wanggou S
Cell Physiol Biochem; 2016; 40(5):1013-1028. PubMed ID: 27941351
[TBL] [Abstract][Full Text] [Related]
2. The cap-translation inhibitor 4EGI-1 induces mitochondrial dysfunction via regulation of mitochondrial dynamic proteins in human glioma U251 cells.
Yang X; Dong QF; Li LW; Huo JL; Li PQ; Fei Z; Zhen HN
Neurochem Int; 2015 Nov; 90():98-106. PubMed ID: 26220902
[TBL] [Abstract][Full Text] [Related]
3. The synergistic inhibition of breast cancer proliferation by combined treatment with 4EGI-1 and MK2206.
Wang H; Huang F; Wang J; Wang P; Lv W; Hong L; Li S; Zhou J
Cell Cycle; 2015; 14(2):232-42. PubMed ID: 25607647
[TBL] [Abstract][Full Text] [Related]
4. The cap-translation inhibitor 4EGI-1 induces apoptosis in multiple myeloma through Noxa induction.
Descamps G; Gomez-Bougie P; Tamburini J; Green A; Bouscary D; Maïga S; Moreau P; Le Gouill S; Pellat-Deceunynck C; Amiot M
Br J Cancer; 2012 May; 106(10):1660-7. PubMed ID: 22510748
[TBL] [Abstract][Full Text] [Related]
5. 4EGI-1 represses cap-dependent translation and regulates genome-wide translation in malignant pleural mesothelioma.
De A; Jacobson BA; Peterson MS; Jay-Dixon J; Kratzke MG; Sadiq AA; Patel MR; Kratzke RA
Invest New Drugs; 2018 Apr; 36(2):217-229. PubMed ID: 29116477
[TBL] [Abstract][Full Text] [Related]
6. The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-mediated apoptosis through c-FLIP Down-regulation and DR5 induction independent of inhibition of cap-dependent protein translation.
Fan S; Li Y; Yue P; Khuri FR; Sun SY
Neoplasia; 2010 Apr; 12(4):346-56. PubMed ID: 20360945
[TBL] [Abstract][Full Text] [Related]
7. 4EGI-1 induces apoptosis and enhances radiotherapy sensitivity in nasopharyngeal carcinoma cells via DR5 induction on 4E-BP1 dephosphorylation.
Wang W; Li J; Wen Q; Luo J; Chu S; Chen L; Qing Z; Xie G; Xu L; Alnemah MM; Li M; Fan S; Zhang H
Oncotarget; 2016 Apr; 7(16):21728-41. PubMed ID: 26942880
[TBL] [Abstract][Full Text] [Related]
8. Tumor suppression by small molecule inhibitors of translation initiation.
Chen L; Aktas BH; Wang Y; He X; Sahoo R; Zhang N; Denoyelle S; Kabha E; Yang H; Freedman RY; Supko JG; Chorev M; Wagner G; Halperin JA
Oncotarget; 2012 Aug; 3(8):869-81. PubMed ID: 22935625
[TBL] [Abstract][Full Text] [Related]
9. Anti-cancer effect of metabotropic glutamate receptor 1 inhibition in human glioma U87 cells: involvement of PI3K/Akt/mTOR pathway.
Zhang C; Yuan XR; Li HY; Zhao ZJ; Liao YW; Wang XY; Su J; Sang SS; Liu Q
Cell Physiol Biochem; 2015; 35(2):419-32. PubMed ID: 25613036
[TBL] [Abstract][Full Text] [Related]
10. Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G.
Moerke NJ; Aktas H; Chen H; Cantel S; Reibarkh MY; Fahmy A; Gross JD; Degterev A; Yuan J; Chorev M; Halperin JA; Wagner G
Cell; 2007 Jan; 128(2):257-67. PubMed ID: 17254965
[TBL] [Abstract][Full Text] [Related]
11. The ERK-MNK-eIF4F signaling pathway mediates TPDHT-induced A549 cell death in vitro and in vivo.
Guo C; Hou Y; Yu X; Zhang F; Wu X; Wu X; Wang L
Food Chem Toxicol; 2020 Mar; 137():111158. PubMed ID: 31991197
[TBL] [Abstract][Full Text] [Related]
12. 3-substituted indazoles as configurationally locked 4EGI-1 mimetics and inhibitors of the eIF4E/eIF4G interaction.
Yefidoff-Freedman R; Chen T; Sahoo R; Chen L; Wagner G; Halperin JA; Aktas BH; Chorev M
Chembiochem; 2014 Mar; 15(4):595-611. PubMed ID: 24458973
[TBL] [Abstract][Full Text] [Related]
13. Down-regulation of 14-3-3β exerts anti-cancer effects through inducing ER stress in human glioma U87 cells: Involvement of CHOP-Wnt pathway.
Cao L; Lei H; Chang MZ; Liu ZQ; Bie XH
Biochem Biophys Res Commun; 2015 Jul; 462(4):389-95. PubMed ID: 25982477
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment.
Wang L; Guo C; Li X; Yu X; Li X; Xu K; Jiang B; Jia X; Li C; Shi D
Eur J Med Chem; 2019 Sep; 177():153-170. PubMed ID: 31132531
[TBL] [Abstract][Full Text] [Related]
15. SUMO-2 promotes mRNA translation by enhancing interaction between eIF4E and eIF4G.
Chen LZ; Li XY; Huang H; Xing W; Guo W; He J; Sun ZY; Luo AX; Liang HP; Hu J; Wang ZG; Xu YS; Xu X
PLoS One; 2014; 9(6):e100457. PubMed ID: 24971752
[TBL] [Abstract][Full Text] [Related]
16. Luteolin induces apoptosis by ROS/ER stress and mitochondrial dysfunction in gliomablastoma.
Wang Q; Wang H; Jia Y; Pan H; Ding H
Cancer Chemother Pharmacol; 2017 May; 79(5):1031-1041. PubMed ID: 28393257
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of oncogenic cap-dependent translation by 4EGI-1 reduces growth, enhances chemosensitivity and alters genome-wide translation in non-small cell lung cancer.
De A; Jacobson BA; Peterson MS; Stelzner ME; Jay-Dixon J; Kratzke MG; Patel MR; Bitterman PB; Kratzke RA
Cancer Gene Ther; 2019 May; 26(5-6):157-165. PubMed ID: 30420719
[TBL] [Abstract][Full Text] [Related]
18. Cap-translation inhibitor, 4EGI-1, restores sensitivity to ABT-737 apoptosis through cap-dependent and -independent mechanisms in chronic lymphocytic leukemia.
Willimott S; Beck D; Ahearne MJ; Adams VC; Wagner SD
Clin Cancer Res; 2013 Jun; 19(12):3212-23. PubMed ID: 23633452
[TBL] [Abstract][Full Text] [Related]
19. The novel phloroglucinol derivative BFP induces apoptosis of glioma cancer through reactive oxygen species and endoplasmic reticulum stress pathways.
Lu DY; Chang CS; Yeh WL; Tang CH; Cheung CW; Leung YM; Liu JF; Wong KL
Phytomedicine; 2012 Sep; 19(12):1093-100. PubMed ID: 22819448
[TBL] [Abstract][Full Text] [Related]
20. Synthesis of rigidified eIF4E/eIF4G inhibitor-1 (4EGI-1) mimetic and their in vitro characterization as inhibitors of protein-protein interaction.
Mahalingam P; Takrouri K; Chen T; Sahoo R; Papadopoulos E; Chen L; Wagner G; Aktas BH; Halperin JA; Chorev M
J Med Chem; 2014 Jun; 57(12):5094-111. PubMed ID: 24827861
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
