215 related articles for article (PubMed ID: 27941853)
1. Antimicrobial mechanism of theaflavins: They target 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the key enzyme of the MEP terpenoid biosynthetic pathway.
Hui X; Yue Q; Zhang DD; Li H; Yang SQ; Gao WY
Sci Rep; 2016 Dec; 6():38945. PubMed ID: 27941853
[TBL] [Abstract][Full Text] [Related]
2. Antimicrobial mechanism of epigallocatechin gallate and gallocatechin gallate: They target 1-deoxy-d-xylulose 5-phosphate reductoisomerase, the key enzyme of the MEP terpenoid biosynthetic pathway.
Hui X; Hua SH; Wu QQ; Li H; Gao WY
Arch Biochem Biophys; 2017 May; 622():1-8. PubMed ID: 28428039
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of green tea and the catechins against 1-deoxy-d-xylulose 5-phosphate reductoisomerase, the key enzyme of the MEP terpenoid biosynthetic pathway.
Hui X; Liu H; Tian FL; Li FF; Li H; Gao WY
Fitoterapia; 2016 Sep; 113():80-4. PubMed ID: 27439219
[TBL] [Abstract][Full Text] [Related]
4. Methylerythritol phosphate pathway to isoprenoids: kinetic modeling and in silico enzyme inhibitions in Plasmodium falciparum.
Singh VK; Ghosh I
FEBS Lett; 2013 Sep; 587(17):2806-17. PubMed ID: 23816706
[TBL] [Abstract][Full Text] [Related]
5. Mechanistic insights into 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a key enzyme of the MEP terpenoid biosynthetic pathway.
Li H; Tian J; Sun W; Qin W; Gao WY
FEBS J; 2013 Nov; 280(22):5896-905. PubMed ID: 24010408
[TBL] [Abstract][Full Text] [Related]
6. Targeting the methyl erythritol phosphate (MEP) pathway for novel antimalarial, antibacterial and herbicidal drug discovery: inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) enzyme.
Singh N; Chevé G; Avery MA; McCurdy CR
Curr Pharm Des; 2007; 13(11):1161-77. PubMed ID: 17430177
[TBL] [Abstract][Full Text] [Related]
7. Inhibitory Activity of Plant Essential Oils against
Yan G; Zhu BR; Tian FL; Hui X; Li H; Li YM; Gao WY
Molecules; 2019 Jul; 24(14):. PubMed ID: 31295807
[TBL] [Abstract][Full Text] [Related]
8. Isoprenoid biosynthesis via the methylerythritol phosphate pathway. Mechanistic investigations of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
Hoeffler JF; Tritsch D; Grosdemange-Billiard C; Rohmer M
Eur J Biochem; 2002 Sep; 269(18):4446-57. PubMed ID: 12230556
[TBL] [Abstract][Full Text] [Related]
9. Mechanism and inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
Murkin AS; Manning KA; Kholodar SA
Bioorg Chem; 2014 Dec; 57():171-185. PubMed ID: 24998420
[TBL] [Abstract][Full Text] [Related]
10. Expression and molecular analysis of the Arabidopsis DXR gene encoding 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the first committed enzyme of the 2-C-methyl-D-erythritol 4-phosphate pathway.
Carretero-Paulet L; Ahumada I; Cunillera N; Rodríguez-Concepción M; Ferrer A; Boronat A; Campos N
Plant Physiol; 2002 Aug; 129(4):1581-91. PubMed ID: 12177470
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and analysis of a fluorinated product analogue as an inhibitor for 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
Munos JW; Pu X; Liu HW
Bioorg Med Chem Lett; 2008 May; 18(10):3090-4. PubMed ID: 18078746
[TBL] [Abstract][Full Text] [Related]
12. Isoprenoid biosynthesis via the MEP pathway. Synthesis of (3,4)-3,4-dihydroxy-5-oxohexylphosphonic acid, an isosteric analogue of 1-deoxy-D-xylulose 5-phosphate, the substrate of the 1-deoxy-D-xylulose 5-phosphate reducto-isomerase.
Meyer O; Grosdemange-Billiard C; Tritsch D; Rohmer M
Org Biomol Chem; 2003 Dec; 1(24):4367-72. PubMed ID: 14685307
[TBL] [Abstract][Full Text] [Related]
13. 1-Deoxy-D-xylulose 5-phosphate reductoisomerase: an overview.
Proteau PJ
Bioorg Chem; 2004 Dec; 32(6):483-93. PubMed ID: 15530989
[TBL] [Abstract][Full Text] [Related]
14. Biosynthesis of terpenoids: 1-deoxy-D-xylulose-5-phosphate reductoisomerase from Escherichia coli is a class B dehydrogenase.
Radykewicz T; Rohdich F; Wungsintaweekul J; Herz S; Kis K; Eisenreich W; Bacher A; Zenk MH; Arigoni D
FEBS Lett; 2000 Jan; 465(2-3):157-60. PubMed ID: 10631325
[TBL] [Abstract][Full Text] [Related]
15. Structural characterization of 1-deoxy-D-xylulose 5-phosphate Reductoisomerase from Vibrio vulnificus.
Ussin NK; Bagnell AM; Offermann LR; Abdulsalam R; Perdue ML; Magee P; Chruszcz M
Biochim Biophys Acta Proteins Proteom; 2018 Dec; 1866(12):1209-1215. PubMed ID: 30278288
[TBL] [Abstract][Full Text] [Related]
16. Growth medium-dependent antimicrobial activity of early stage MEP pathway inhibitors.
Sanders S; Bartee D; Harrison MJ; Phillips PD; Koppisch AT; Freel Meyers CL
PLoS One; 2018; 13(5):e0197638. PubMed ID: 29771999
[TBL] [Abstract][Full Text] [Related]
17. A high-throughput screening assay for simultaneous selection of inhibitors of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate synthase (Dxs) or 1-deoxy-D-xylulose 5-phosphate reductoisomerase (Dxr).
Humnabadkar V; Jha RK; Ghatnekar N; De Sousa SM
J Biomol Screen; 2011 Mar; 16(3):303-12. PubMed ID: 21335601
[TBL] [Abstract][Full Text] [Related]
18. Disruption of the 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) gene results in albino, dwarf and defects in trichome initiation and stomata closure in Arabidopsis.
Xing S; Miao J; Li S; Qin G; Tang S; Li H; Gu H; Qu LJ
Cell Res; 2010 Jun; 20(6):688-700. PubMed ID: 20404857
[TBL] [Abstract][Full Text] [Related]
19. α,α-Difluorophosphonohydroxamic Acid Derivatives among the Best Antibacterial Fosmidomycin Analogues.
Dreneau A; Krebs FS; Munier M; Ngov C; Tritsch D; Lièvremont D; Rohmer M; Grosdemange-Billiard C
Molecules; 2021 Aug; 26(16):. PubMed ID: 34443699
[TBL] [Abstract][Full Text] [Related]
20. A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis.
Takahashi S; Kuzuyama T; Watanabe H; Seto H
Proc Natl Acad Sci U S A; 1998 Aug; 95(17):9879-84. PubMed ID: 9707569
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
