854 related articles for article (PubMed ID: 27955654)
1. Depletion of SAG/RBX2 E3 ubiquitin ligase suppresses prostate tumorigenesis via inactivation of the PI3K/AKT/mTOR axis.
Tan M; Xu J; Siddiqui J; Feng F; Sun Y
Mol Cancer; 2016 Dec; 15(1):81. PubMed ID: 27955654
[TBL] [Abstract][Full Text] [Related]
2. Inactivation of Sag/Rbx2/Roc2 e3 ubiquitin ligase triggers senescence and inhibits kras-induced immortalization.
Tan M; Li H; Sun Y
Neoplasia; 2015 Jan; 17(1):114-23. PubMed ID: 25622904
[TBL] [Abstract][Full Text] [Related]
3. Transgenic expression of Sag/Rbx2 E3 causes early stage tumor promotion, late stage cytogenesis and acinar loss in the Kras-PDAC model.
Zhang Q; Wei D; Tan M; Li H; Morgan MA; Sun Y
Neoplasia; 2020 Apr; 22(6):242-252. PubMed ID: 32339950
[TBL] [Abstract][Full Text] [Related]
4. Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis.
Li H; Tan M; Jia L; Wei D; Zhao Y; Chen G; Xu J; Zhao L; Thomas D; Beer DG; Sun Y
J Clin Invest; 2014 Feb; 124(2):835-46. PubMed ID: 24430184
[TBL] [Abstract][Full Text] [Related]
5. IMP3 accelerates the progression of prostate cancer through inhibiting PTEN expression in a SMURF1-dependent way.
Zhang X; Wang D; Liu B; Jin X; Wang X; Pan J; Tu W; Shao Y
J Exp Clin Cancer Res; 2020 Sep; 39(1):190. PubMed ID: 32938489
[TBL] [Abstract][Full Text] [Related]
6. Alpha1-ACT Functions as a Tumour Suppressor in Hepatocellular Carcinoma by Inhibiting the PI3K/AKT/mTOR Signalling Pathway via Activation of PTEN.
Zhu H; Liu Q; Tang J; Xie Y; Xu X; Huang R; Zhang Y; Jin K; Sun B
Cell Physiol Biochem; 2017; 41(6):2289-2306. PubMed ID: 28456796
[TBL] [Abstract][Full Text] [Related]
7. AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis.
Li N; Xue W; Yuan H; Dong B; Ding Y; Liu Y; Jiang M; Kan S; Sun T; Ren J; Pan Q; Li X; Zhang P; Hu G; Wang Y; Wang X; Li Q; Qin J
J Clin Invest; 2017 Apr; 127(4):1284-1302. PubMed ID: 28319045
[TBL] [Abstract][Full Text] [Related]
8. Endothelial deletion of Sag/Rbx2/Roc2 E3 ubiquitin ligase causes embryonic lethality and blocks tumor angiogenesis.
Tan M; Li H; Sun Y
Oncogene; 2014 Oct; 33(44):5211-20. PubMed ID: 24213570
[TBL] [Abstract][Full Text] [Related]
9. Functional characterization of SAG/RBX2/ROC2/RNF7, an antioxidant protein and an E3 ubiquitin ligase.
Sun Y; Li H
Protein Cell; 2013 Feb; 4(2):103-16. PubMed ID: 23136067
[TBL] [Abstract][Full Text] [Related]
10. DEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signals.
Chen X; Xiong X; Cui D; Yang F; Wei D; Li H; Shu J; Bi Y; Dai X; Gong L; Sun Y; Zhao Y
Oncogene; 2020 Feb; 39(7):1557-1571. PubMed ID: 31685947
[TBL] [Abstract][Full Text] [Related]
11. GOLM1 promotes prostate cancer progression through activating PI3K-AKT-mTOR signaling.
Yan G; Ru Y; Wu K; Yan F; Wang Q; Wang J; Pan T; Zhang M; Han H; Li X; Zou L
Prostate; 2018 Feb; 78(3):166-177. PubMed ID: 29181846
[TBL] [Abstract][Full Text] [Related]
12. miR-410-3p promotes prostate cancer progression via regulating PTEN/AKT/mTOR signaling pathway.
Zhang Y; Zhang D; Lv J; Wang S; Zhang Q
Biochem Biophys Res Commun; 2018 Sep; 503(4):2459-2465. PubMed ID: 29969630
[TBL] [Abstract][Full Text] [Related]
13. Sirtuin 6 inhibits colon cancer progression by modulating PTEN/AKT signaling.
Tian J; Yuan L
Biomed Pharmacother; 2018 Oct; 106():109-116. PubMed ID: 29957460
[TBL] [Abstract][Full Text] [Related]
14. Brassinin induces apoptosis in PC-3 human prostate cancer cells through the suppression of PI3K/Akt/mTOR/S6K1 signaling cascades.
Kim SM; Park JH; Kim KD; Nam D; Shim BS; Kim SH; Ahn KS; Choi SH; Ahn KS
Phytother Res; 2014 Mar; 28(3):423-31. PubMed ID: 23686889
[TBL] [Abstract][Full Text] [Related]
15. SIX1 reduces the expression of PTEN via activating PI3K/AKT signal to promote cell proliferation and tumorigenesis in osteosarcoma.
Yu C; Zhang B; Li YL; Yu XR
Biomed Pharmacother; 2018 Sep; 105():10-17. PubMed ID: 29807230
[TBL] [Abstract][Full Text] [Related]
16. Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis.
Xie CM; Wei D; Zhao L; Marchetto S; Mei L; Borg JP; Sun Y
J Cell Biol; 2015 Jun; 209(5):721-37. PubMed ID: 26056141
[TBL] [Abstract][Full Text] [Related]
17. GPCR48/LGR4 promotes tumorigenesis of prostate cancer via PI3K/Akt signaling pathway.
Liang F; Yue J; Wang J; Zhang L; Fan R; Zhang H; Zhang Q
Med Oncol; 2015 Mar; 32(3):49. PubMed ID: 25636507
[TBL] [Abstract][Full Text] [Related]
18. RUNX2 overexpression and PTEN haploinsufficiency cooperate to promote CXCR7 expression and cellular trafficking, AKT hyperactivation and prostate tumorigenesis.
Bai Y; Yang Y; Yan Y; Zhong J; Blee AM; Pan Y; Ma T; Karnes RJ; Jimenez R; Xu W; Huang H
Theranostics; 2019; 9(12):3459-3475. PubMed ID: 31281490
[No Abstract] [Full Text] [Related]
19. Knockdown of DEPTOR inhibits cell proliferation and increases chemosensitivity to melphalan in human multiple myeloma RPMI-8226 cells via inhibiting PI3K/AKT activity.
Zhang HR; Chen JM; Zeng ZY; Que WZ
J Int Med Res; 2013 Jun; 41(3):584-95. PubMed ID: 23613505
[TBL] [Abstract][Full Text] [Related]
20. Loss of ATF3 promotes Akt activation and prostate cancer development in a Pten knockout mouse model.
Wang Z; Xu D; Ding HF; Kim J; Zhang J; Hai T; Yan C
Oncogene; 2015 Sep; 34(38):4975-84. PubMed ID: 25531328
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
