427 related articles for article (PubMed ID: 27956626)
1. Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice.
Carr MI; Roderick JE; Zhang H; Woda BA; Kelliher MA; Jones SN
Proc Natl Acad Sci U S A; 2016 Dec; 113(52):15024-15029. PubMed ID: 27956626
[TBL] [Abstract][Full Text] [Related]
2. Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis.
Carr MI; Roderick JE; Gannon HS; Kelliher MA; Jones SN
Cell Rep; 2016 Sep; 16(10):2618-2629. PubMed ID: 27568562
[TBL] [Abstract][Full Text] [Related]
3. ATM phosphorylation of Mdm2 Ser394 regulates the amplitude and duration of the DNA damage response in mice.
Gannon HS; Woda BA; Jones SN
Cancer Cell; 2012 May; 21(5):668-679. PubMed ID: 22624716
[TBL] [Abstract][Full Text] [Related]
4. c-Abl phosphorylates Hdm2 at tyrosine 276 in response to DNA damage and regulates interaction with ARF.
Dias SS; Milne DM; Meek DW
Oncogene; 2006 Oct; 25(50):6666-71. PubMed ID: 16702947
[TBL] [Abstract][Full Text] [Related]
5. Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation.
Goldberg Z; Vogt Sionov R; Berger M; Zwang Y; Perets R; Van Etten RA; Oren M; Taya Y; Haupt Y
EMBO J; 2002 Jul; 21(14):3715-27. PubMed ID: 12110584
[TBL] [Abstract][Full Text] [Related]
6. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
Maya R; Balass M; Kim ST; Shkedy D; Leal JF; Shifman O; Moas M; Buschmann T; Ronai Z; Shiloh Y; Kastan MB; Katzir E; Oren M
Genes Dev; 2001 May; 15(9):1067-77. PubMed ID: 11331603
[TBL] [Abstract][Full Text] [Related]
7. Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage.
Khosravi R; Maya R; Gottlieb T; Oren M; Shiloh Y; Shkedy D
Proc Natl Acad Sci U S A; 1999 Dec; 96(26):14973-7. PubMed ID: 10611322
[TBL] [Abstract][Full Text] [Related]
8. c-Abl phosphorylation of Mdm2 facilitates Mdm2-Mdmx complex formation.
Waning DL; Lehman JA; Batuello CN; Mayo LD
J Biol Chem; 2011 Jan; 286(1):216-22. PubMed ID: 21081495
[TBL] [Abstract][Full Text] [Related]
9. c-Abl phosphorylates Hdmx and regulates its interaction with p53.
Zuckerman V; Lenos K; Popowicz GM; Silberman I; Grossman T; Marine JC; Holak TA; Jochemsen AG; Haupt Y
J Biol Chem; 2009 Feb; 284(6):4031-9. PubMed ID: 19075013
[TBL] [Abstract][Full Text] [Related]
10. c-Abl neutralizes the inhibitory effect of Mdm2 on p53.
Sionov RV; Moallem E; Berger M; Kazaz A; Gerlitz O; Ben-Neriah Y; Oren M; Haupt Y
J Biol Chem; 1999 Mar; 274(13):8371-4. PubMed ID: 10085066
[TBL] [Abstract][Full Text] [Related]
11. A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network.
Toledo F; Krummel KA; Lee CJ; Liu CW; Rodewald LW; Tang M; Wahl GM
Cancer Cell; 2006 Apr; 9(4):273-85. PubMed ID: 16616333
[TBL] [Abstract][Full Text] [Related]
12. Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function.
Kamijo T; van de Kamp E; Chong MJ; Zindy F; Diehl JA; Sherr CJ; McKinnon PJ
Cancer Res; 1999 May; 59(10):2464-9. PubMed ID: 10344759
[TBL] [Abstract][Full Text] [Related]
13. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
[TBL] [Abstract][Full Text] [Related]
14. Stabilization of p53 by CP-31398 inhibits ubiquitination without altering phosphorylation at serine 15 or 20 or MDM2 binding.
Wang W; Takimoto R; Rastinejad F; El-Deiry WS
Mol Cell Biol; 2003 Mar; 23(6):2171-81. PubMed ID: 12612087
[TBL] [Abstract][Full Text] [Related]
15. Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis.
Sluss HK; Gannon H; Coles AH; Shen Q; Eischen CM; Jones SN
Mol Cancer Res; 2010 Feb; 8(2):216-22. PubMed ID: 20145032
[TBL] [Abstract][Full Text] [Related]
16. ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation.
Meulmeester E; Pereg Y; Shiloh Y; Jochemsen AG
Cell Cycle; 2005 Sep; 4(9):1166-70. PubMed ID: 16082221
[TBL] [Abstract][Full Text] [Related]
17. Phosphorylation of serine 18 regulates distinct p53 functions in mice.
Sluss HK; Armata H; Gallant J; Jones SN
Mol Cell Biol; 2004 Feb; 24(3):976-84. PubMed ID: 14729946
[TBL] [Abstract][Full Text] [Related]
18. F-box protein FBXO31 directs degradation of MDM2 to facilitate p53-mediated growth arrest following genotoxic stress.
Malonia SK; Dutta P; Santra MK; Green MR
Proc Natl Acad Sci U S A; 2015 Jul; 112(28):8632-7. PubMed ID: 26124108
[TBL] [Abstract][Full Text] [Related]
19. C-Abl as a modulator of p53.
Levav-Cohen Y; Goldberg Z; Zuckerman V; Grossman T; Haupt S; Haupt Y
Biochem Biophys Res Commun; 2005 Jun; 331(3):737-49. PubMed ID: 15865930
[TBL] [Abstract][Full Text] [Related]
20. HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage.
Pääjärvi G; Roudier E; Crisby M; Högberg J; Stenius U
FASEB J; 2005 Mar; 19(3):476-8. PubMed ID: 15625077
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
