These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
275 related articles for article (PubMed ID: 27960087)
1. Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors. Huang X; Motea EA; Moore ZR; Yao J; Dong Y; Chakrabarti G; Kilgore JA; Silvers MA; Patidar PL; Cholka A; Fattah F; Cha Y; Anderson GG; Kusko R; Peyton M; Yan J; Xie XJ; Sarode V; Williams NS; Minna JD; Beg M; Gerber DE; Bey EA; Boothman DA Cancer Cell; 2016 Dec; 30(6):940-952. PubMed ID: 27960087 [TBL] [Abstract][Full Text] [Related]
2. Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone. Chakrabarti G; Silvers MA; Ilcheva M; Liu Y; Moore ZR; Luo X; Gao J; Anderson G; Liu L; Sarode V; Gerber DE; Burma S; DeBerardinis RJ; Gerson SL; Boothman DA Sci Rep; 2015 Nov; 5():17066. PubMed ID: 26602448 [TBL] [Abstract][Full Text] [Related]
3. Catalase abrogates β-lapachone-induced PARP1 hyperactivation-directed programmed necrosis in NQO1-positive breast cancers. Bey EA; Reinicke KE; Srougi MC; Varnes M; Anderson VE; Pink JJ; Li LS; Patel M; Cao L; Moore Z; Rommel A; Boatman M; Lewis C; Euhus DM; Bornmann WG; Buchsbaum DJ; Spitz DR; Gao J; Boothman DA Mol Cancer Ther; 2013 Oct; 12(10):2110-20. PubMed ID: 23883585 [TBL] [Abstract][Full Text] [Related]
4. An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by beta-lapachone. Bey EA; Bentle MS; Reinicke KE; Dong Y; Yang CR; Girard L; Minna JD; Bornmann WG; Gao J; Boothman DA Proc Natl Acad Sci U S A; 2007 Jul; 104(28):11832-7. PubMed ID: 17609380 [TBL] [Abstract][Full Text] [Related]
5. An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis. Huang X; Dong Y; Bey EA; Kilgore JA; Bair JS; Li LS; Patel M; Parkinson EI; Wang Y; Williams NS; Gao J; Hergenrother PJ; Boothman DA Cancer Res; 2012 Jun; 72(12):3038-47. PubMed ID: 22532167 [TBL] [Abstract][Full Text] [Related]
6. The NQO1 bioactivatable drug, β-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism. Silvers MA; Deja S; Singh N; Egnatchik RA; Sudderth J; Luo X; Beg MS; Burgess SC; DeBerardinis RJ; Boothman DA; Merritt ME J Biol Chem; 2017 Nov; 292(44):18203-18216. PubMed ID: 28916726 [TBL] [Abstract][Full Text] [Related]
7. NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone. Moore Z; Chakrabarti G; Luo X; Ali A; Hu Z; Fattah FJ; Vemireddy R; DeBerardinis RJ; Brekken RA; Boothman DA Cell Death Dis; 2015 Jan; 6(1):e1599. PubMed ID: 25590809 [TBL] [Abstract][Full Text] [Related]
8. Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of β-lapachone for pancreatic cancer therapy. Li LS; Bey EA; Dong Y; Meng J; Patra B; Yan J; Xie XJ; Brekken RA; Barnett CC; Bornmann WG; Gao J; Boothman DA Clin Cancer Res; 2011 Jan; 17(2):275-85. PubMed ID: 21224367 [TBL] [Abstract][Full Text] [Related]
9. NQO1-dependent, Tumor-selective Radiosensitization of Non-small Cell Lung Cancers. Motea EA; Huang X; Singh N; Kilgore JA; Williams NS; Xie XJ; Gerber DE; Beg MS; Bey EA; Boothman DA Clin Cancer Res; 2019 Apr; 25(8):2601-2609. PubMed ID: 30617135 [TBL] [Abstract][Full Text] [Related]
10. Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone. Torrente L; Prieto-Farigua N; Falzone A; Elkins CM; Boothman DA; Haura EB; DeNicola GM Redox Biol; 2020 Feb; 30():101440. PubMed ID: 32007910 [TBL] [Abstract][Full Text] [Related]
11. β-Lapachone induces programmed necrosis through the RIP1-PARP-AIF-dependent pathway in human hepatocellular carcinoma SK-Hep1 cells. Park EJ; Min KJ; Lee TJ; Yoo YH; Kim YS; Kwon TK Cell Death Dis; 2014 May; 5(5):e1230. PubMed ID: 24832602 [TBL] [Abstract][Full Text] [Related]
12. PCNA inhibition enhances the cytotoxicity of β-lapachone in NQO1-Positive cancer cells by augmentation of oxidative stress-induced DNA damage. Su X; Wang J; Jiang L; Chen Y; Lu T; Mendonca MS; Huang X Cancer Lett; 2021 Oct; 519():304-314. PubMed ID: 34329742 [TBL] [Abstract][Full Text] [Related]
13. NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer. Li LS; Reddy S; Lin ZH; Liu S; Park H; Chun SG; Bornmann WG; Thibodeaux J; Yan J; Chakrabarti G; Xie XJ; Sumer BD; Boothman DA; Yordy JS Mol Cancer Ther; 2016 Jul; 15(7):1757-67. PubMed ID: 27196777 [TBL] [Abstract][Full Text] [Related]
14. Tumor-selective, futile redox cycle-induced bystander effects elicited by NQO1 bioactivatable radiosensitizing drugs in triple-negative breast cancers. Cao L; Li LS; Spruell C; Xiao L; Chakrabarti G; Bey EA; Reinicke KE; Srougi MC; Moore Z; Dong Y; Vo P; Kabbani W; Yang CR; Wang X; Fattah F; Morales JC; Motea EA; Bornmann WG; Yordy JS; Boothman DA Antioxid Redox Signal; 2014 Jul; 21(2):237-50. PubMed ID: 24512128 [TBL] [Abstract][Full Text] [Related]
15. DNA damage induced by KP372-1 hyperactivates PARP1 and enhances lethality of pancreatic cancer cells with PARP inhibition. Viera T; Patidar PL Sci Rep; 2020 Nov; 10(1):20210. PubMed ID: 33214574 [TBL] [Abstract][Full Text] [Related]
16. A self-amplified nanocatalytic system for achieving "1 + 1 + 1 > 3" chemodynamic therapy on triple negative breast cancer. Zhou L; Chen J; Sun Y; Chai K; Zhu Z; Wang C; Chen M; Han W; Hu X; Li R; Yao T; Li H; Dong C; Shi S J Nanobiotechnology; 2021 Sep; 19(1):261. PubMed ID: 34481495 [TBL] [Abstract][Full Text] [Related]
17. β-Lapachone and Paclitaxel Combination Micelles with Improved Drug Encapsulation and Therapeutic Synergy as Novel Nanotherapeutics for NQO1-Targeted Cancer Therapy. Zhang L; Chen Z; Yang K; Liu C; Gao J; Qian F Mol Pharm; 2015 Nov; 12(11):3999-4010. PubMed ID: 26415823 [TBL] [Abstract][Full Text] [Related]
18. Esterase-activatable β-lapachone prodrug micelles for NQO1-targeted lung cancer therapy. Ma X; Huang X; Moore Z; Huang G; Kilgore JA; Wang Y; Hammer S; Williams NS; Boothman DA; Gao J J Control Release; 2015 Feb; 200():201-11. PubMed ID: 25542645 [TBL] [Abstract][Full Text] [Related]
19. Prostate cancer radiosensitization through poly(ADP-Ribose) polymerase-1 hyperactivation. Dong Y; Bey EA; Li LS; Kabbani W; Yan J; Xie XJ; Hsieh JT; Gao J; Boothman DA Cancer Res; 2010 Oct; 70(20):8088-96. PubMed ID: 20940411 [TBL] [Abstract][Full Text] [Related]
20. Sulindac compounds facilitate the cytotoxicity of β-lapachone by up-regulation of NAD(P)H quinone oxidoreductase in human lung cancer cells. Kung HN; Weng TY; Liu YL; Lu KS; Chau YP PLoS One; 2014; 9(2):e88122. PubMed ID: 24505400 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]