BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 27974147)

  • 1. Dual activities of ritanserin and R59022 as DGKα inhibitors and serotonin receptor antagonists.
    Boroda S; Niccum M; Raje V; Purow BW; Harris TE
    Biochem Pharmacol; 2017 Jan; 123():29-39. PubMed ID: 27974147
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of ritanserin analogs that display DGK isoform specificity.
    Granade ME; Manigat LC; Lemke MC; Purow BW; Harris TE
    Biochem Pharmacol; 2022 Mar; 197():114908. PubMed ID: 34999054
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluations of the selectivities of the diacylglycerol kinase inhibitors R59022 and R59949 among diacylglycerol kinase isozymes using a new non-radioactive assay method.
    Sato M; Liu K; Sasaki S; Kunii N; Sakai H; Mizuno H; Saga H; Sakane F
    Pharmacology; 2013; 92(1-2):99-107. PubMed ID: 23949095
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of a novel DGKα inhibitor for XLP-1 therapy by virtual screening.
    Velnati S; Ruffo E; Massarotti A; Talmon M; Varma KSS; Gesu A; Fresu LG; Snow AL; Bertoni A; Capello D; Tron GC; Graziani A; Baldanzi G
    Eur J Med Chem; 2019 Feb; 164():378-390. PubMed ID: 30611057
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Diacylglycerol kinase inhibitor R59022-induced autophagy and apoptosis in the neuronal cell line NG108-15.
    Takita T; Konuma T; Hanazato M; Inoue H
    Arch Biochem Biophys; 2011 May; 509(2):197-201. PubMed ID: 21338572
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deconstructing Lipid Kinase Inhibitors by Chemical Proteomics.
    McCloud RL; Franks CE; Campbell ST; Purow BW; Harris TE; Hsu KL
    Biochemistry; 2018 Jan; 57(2):231-236. PubMed ID: 29155586
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Diacylglycerol Kinase Inhibition Reduces Airway Contraction by Negative Feedback Regulation of Gq-Signaling.
    Sharma P; Yadav SK; Shah SD; Javed E; Lim JM; Pan S; Nayak AP; Panettieri RA; Penn RB; Kambayashi T; Deshpande DA
    Am J Respir Cell Mol Biol; 2021 Dec; 65(6):658-671. PubMed ID: 34293268
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Diacylglycerol kinase α inactivation is an integral component of the costimulatory pathway that amplifies TCR signals.
    Arranz-Nicolás J; Ogando J; Soutar D; Arcos-Pérez R; Meraviglia-Crivelli D; Mañes S; Mérida I; Ávila-Flores A
    Cancer Immunol Immunother; 2018 Jun; 67(6):965-980. PubMed ID: 29572701
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selectivity of the diacylglycerol kinase inhibitor 3-[2-(4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl)ethyl]-2, 3-dihydro-2-thioxo-4(1H)quinazolinone (R59949) among diacylglycerol kinase subtypes.
    Jiang Y; Sakane F; Kanoh H; Walsh JP
    Biochem Pharmacol; 2000 Apr; 59(7):763-72. PubMed ID: 10718334
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of the diacylglycerol kinase inhibitor, R59022, on TSH-stimulated iodide organification in porcine thyroid cells.
    Matowe WC; Ginsberg J
    Pharmacology; 1996 Dec; 53(6):376-83. PubMed ID: 9032802
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A diacylglycerol kinase inhibitor, R59022, stimulates glucose transport through a MKK3/6-p38 signaling pathway in skeletal muscle cells.
    Takahashi N; Nagamine M; Tanno S; Motomura W; Kohgo Y; Okumura T
    Biochem Biophys Res Commun; 2007 Aug; 360(1):244-50. PubMed ID: 17588539
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Arabidopsis AtDGK7, the smallest member of plant diacylglycerol kinases (DGKs), displays unique biochemical features and saturates at low substrate concentration: the DGK inhibitor R59022 differentially affects AtDGK2 and AtDGK7 activity in vitro and alters plant growth and development.
    Gómez-Merino FC; Arana-Ceballos FA; Trejo-Téllez LI; Skirycz A; Brearley CA; Dörmann P; Mueller-Roeber B
    J Biol Chem; 2005 Oct; 280(41):34888-99. PubMed ID: 16081412
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differentiation of HL-60 cells to granulocytes involves regulation of select diacylglycerol kinases (DGKs).
    Batista EL; Warbington M; Badwey JA; Van Dyke TE
    J Cell Biochem; 2005 Mar; 94(4):774-93. PubMed ID: 15578578
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular Pathways: Targeting Diacylglycerol Kinase Alpha in Cancer.
    Purow B
    Clin Cancer Res; 2015 Nov; 21(22):5008-12. PubMed ID: 26420856
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Ligand Binding Landscape of Diacylglycerol Kinases.
    Franks CE; Campbell ST; Purow BW; Harris TE; Hsu KL
    Cell Chem Biol; 2017 Jul; 24(7):870-880.e5. PubMed ID: 28712745
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel diacylglycerol kinase α-selective inhibitor, CU-3, induces cancer cell apoptosis and enhances immune response.
    Liu K; Kunii N; Sakuma M; Yamaki A; Mizuno S; Sato M; Sakai H; Kado S; Kumagai K; Kojima H; Okabe T; Nagano T; Shirai Y; Sakane F
    J Lipid Res; 2016 Mar; 57(3):368-79. PubMed ID: 26768655
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fatty acids inhibit growth-factor-induced diacylglycerol kinase alpha activation in vascular smooth-muscle cells.
    Du X; Jiang Y; Qian W; Lu X; Walsh JP
    Biochem J; 2001 Jul; 357(Pt 1):275-82. PubMed ID: 11415460
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha.
    Olmez I; Love S; Xiao A; Manigat L; Randolph P; McKenna BD; Neal BP; Boroda S; Li M; Brenneman B; Abounader R; Floyd D; Lee J; Nakano I; Godlewski J; Bronisz A; Sulman EP; Mayo M; Gioeli D; Weber M; Harris TE; Purow B
    Neuro Oncol; 2018 Jan; 20(2):192-202. PubMed ID: 29048560
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Streptococcus mutans diacylglycerol kinase homologue: a potential target for anti-caries chemotherapy.
    Shibata Y; Kawada-Matsuo M; Shirai Y; Saito N; Li D; Yamashita Y
    J Med Microbiol; 2011 May; 60(Pt 5):625-630. PubMed ID: 21317193
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Diacylglycerol kinase inhibitor R59022 attenuates conjugated linoleic acid-mediated inflammation in human adipocytes.
    Martinez K; Shyamasundar S; Kennedy A; Chuang CC; Marsh A; Kincaid J; Reid T; McIntosh M
    J Lipid Res; 2013 Mar; 54(3):662-670. PubMed ID: 23264678
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.