These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

108 related articles for article (PubMed ID: 27984797)

  • 1. On the mechanism of substrate/non-substrate recognition by P-glycoprotein.
    Mukhametov A; Raevsky OA
    J Mol Graph Model; 2017 Jan; 71():227-232. PubMed ID: 27984797
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional role of the linker region in purified human P-glycoprotein.
    Sato T; Kodan A; Kimura Y; Ueda K; Nakatsu T; Kato H
    FEBS J; 2009 Jul; 276(13):3504-16. PubMed ID: 19490125
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Homology Modeling of the Human P-glycoprotein (ABCB1) and Insights into Ligand Binding through Molecular Docking Studies.
    Mora Lagares L; Minovski N; Caballero Alfonso AY; Benfenati E; Wellens S; Culot M; Gosselet F; Novič M
    Int J Mol Sci; 2020 Jun; 21(11):. PubMed ID: 32517082
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations in the nucleotide-binding sites of P-glycoprotein that affect substrate specificity modulate substrate-induced adenosine triphosphatase activity.
    Beaudet L; Urbatsch IL; Gros P
    Biochemistry; 1998 Jun; 37(25):9073-82. PubMed ID: 9636053
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thiol-reactive drug substrates of human P-glycoprotein label the same sites to activate ATPase activity in membranes or dodecyl maltoside detergent micelles.
    Loo TW; Clarke DM
    Biochem Biophys Res Commun; 2017 Jul; 488(4):573-577. PubMed ID: 28533092
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A significant mechanism of molecular recognition between bioflavonoids and P-glycoprotein leading to herb-drug interactions.
    Wongrattanakamon P; Nimmanpipug P; Sirithunyalug B; Chansakaow S; Jiranusornkul S
    Toxicol Mech Methods; 2018 Jan; 28(1):1-11. PubMed ID: 28678657
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural and dynamic perspectives on the promiscuous transport activity of P-glycoprotein.
    Subramanian N; Condic-Jurkic K; O'Mara ML
    Neurochem Int; 2016 Sep; 98():146-52. PubMed ID: 27180050
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular dynamics simulation and molecular docking studies of 1,4-Dihydropyridines as P-glycoprotein's allosteric inhibitors.
    Shahraki O; Zargari F; Edraki N; Khoshneviszadeh M; Firuzi O; Miri R
    J Biomol Struct Dyn; 2018 Jan; 36(1):112-125. PubMed ID: 27981890
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The extracellular loop between TM5 and TM6 of P-glycoprotein is required for reactivity with monoclonal antibody UIC2.
    Zhou Y; Gottesman MM; Pastan I
    Arch Biochem Biophys; 1999 Jul; 367(1):74-80. PubMed ID: 10375401
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evidence for the critical role of transmembrane helices 1 and 7 in substrate transport by human P-glycoprotein (ABCB1).
    Sajid A; Lusvarghi S; Chufan EE; Ambudkar SV
    PLoS One; 2018; 13(9):e0204693. PubMed ID: 30265721
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation and function of the multidrug resistance genes in liver.
    Silverman JA; Thorgeirsson SS
    Prog Liver Dis; 1995; 13():101-23. PubMed ID: 9224499
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In Silico and in Vitro Screening for P-Glycoprotein Interaction with Tenofovir, Darunavir, and Dapivirine: An Antiretroviral Drug Combination for Topical Prevention of Colorectal HIV Transmission.
    Swedrowska M; Jamshidi S; Kumar A; Kelly C; Rahman KM; Forbes B
    Mol Pharm; 2017 Aug; 14(8):2660-2669. PubMed ID: 28648081
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses.
    Kadioglu O; Saeed ME; Valoti M; Frosini M; Sgaragli G; Efferth T
    Biochem Pharmacol; 2016 Mar; 104():42-51. PubMed ID: 26807479
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modifying the sugar moieties of daunorubicin overcomes P-gp-mediated multidrug resistance.
    Battisti RF; Zhong Y; Fang L; Gibbs S; Shen J; Nadas J; Zhang G; Sun D
    Mol Pharm; 2007; 4(1):140-53. PubMed ID: 17274671
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interaction of transported drugs with the lipid bilayer and P-glycoprotein through a solvation exchange mechanism.
    Omote H; Al-Shawi MK
    Biophys J; 2006 Jun; 90(11):4046-59. PubMed ID: 16565061
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reversal of multidrug resistance by Marsdenia tenacissima and its main active ingredients polyoxypregnanes.
    To KKW; Wu X; Yin C; Chai S; Yao S; Kadioglu O; Efferth T; Ye Y; Lin G
    J Ethnopharmacol; 2017 May; 203():110-119. PubMed ID: 28363522
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A new intestinal cell culture model to discriminate the relative contribution of P-gp and BCRP on transport of substrates such as imatinib.
    Graber-Maier A; Gutmann H; Drewe J
    Mol Pharm; 2010 Oct; 7(5):1618-28. PubMed ID: 20701289
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutagenesis of transmembrane domain 11 of P-glycoprotein by alanine scanning.
    Hanna M; Brault M; Kwan T; Kast C; Gros P
    Biochemistry; 1996 Mar; 35(11):3625-35. PubMed ID: 8639515
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Celastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance.
    Muñoz-Martínez F; Lu P; Cortés-Selva F; Pérez-Victoria JM; Jiménez IA; Ravelo AG; Sharom FJ; Gamarro F; Castanys S
    Cancer Res; 2004 Oct; 64(19):7130-8. PubMed ID: 15466210
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure based investigation on the binding interaction of transport proteins in leishmaniasis: insights from molecular simulation.
    Singh S; Mandlik V
    Mol Biosyst; 2015 May; 11(5):1251-9. PubMed ID: 25761976
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.