BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

578 related articles for article (PubMed ID: 27989873)

  • 1. A platycoside-rich fraction from the root of Platycodon grandiflorum enhances cell death in A549 human lung carcinoma cells via mainly AMPK/mTOR/AKT signal-mediated autophagy induction.
    Yim NH; Hwang YH; Liang C; Ma JY
    J Ethnopharmacol; 2016 Dec; 194():1060-1068. PubMed ID: 27989873
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer.
    Teng JF; Qin DL; Mei QB; Qiu WQ; Pan R; Xiong R; Zhao Y; Law BY; Wong VK; Tang Y; Yu CL; Zhang F; Wu JM; Wu AG
    Pharmacol Res; 2019 Sep; 147():104396. PubMed ID: 31404628
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Luteoloside induces G
    Zhou M; Shen S; Zhao X; Gong X
    Biochem Biophys Res Commun; 2017 Dec; 494(1-2):263-269. PubMed ID: 29024631
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Apoptosis induced by the methanol extract of Salvia miltiorrhiza Bunge in non-small cell lung cancer through PTEN-mediated inhibition of PI3K/Akt pathway.
    Ye YT; Zhong W; Sun P; Wang D; Wang C; Hu LM; Qian JQ
    J Ethnopharmacol; 2017 Mar; 200():107-116. PubMed ID: 28088493
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Delicaflavone induces autophagic cell death in lung cancer via Akt/mTOR/p70S6K signaling pathway.
    Sui Y; Yao H; Li S; Jin L; Shi P; Li Z; Wang G; Lin S; Wu Y; Li Y; Huang L; Liu Q; Lin X
    J Mol Med (Berl); 2017 Mar; 95(3):311-322. PubMed ID: 27838742
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Saponins from the roots of Platycodon grandiflorum suppresses TGFβ1-induced epithelial-mesenchymal transition via repression of PI3K/Akt, ERK1/2 and Smad2/3 pathway in human lung carcinoma A549 cells.
    Choi JH; Hwang YP; Kim HG; Khanal T; Do MT; Jin SW; Han HJ; Lee HS; Lee YC; Chung YC; Jeong TC; Jeong HG
    Nutr Cancer; 2014; 66(1):140-51. PubMed ID: 24341702
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Isolation of a new saponin and cytotoxic effect of saponins from the root of Platycodon grandiflorum on human tumor cell lines.
    Kim YS; Kim JS; Choi SU; Kim JS; Lee HS; Roh SH; Jeong YC; Kim YK; Ryu SY
    Planta Med; 2005 Jun; 71(6):566-8. PubMed ID: 15971131
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antitumor activity of curcumin by modulation of apoptosis and autophagy in human lung cancer A549 cells through inhibiting PI3K/Akt/mTOR pathway.
    Liu F; Gao S; Yang Y; Zhao X; Fan Y; Ma W; Yang D; Yang A; Yu Y
    Oncol Rep; 2018 Mar; 39(3):1523-1531. PubMed ID: 29328421
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Eriocalyxin B, a novel autophagy inducer, exerts anti-tumor activity through the suppression of Akt/mTOR/p70S6K signaling pathway in breast cancer.
    Zhou X; Yue GG; Chan AM; Tsui SK; Fung KP; Sun H; Pu J; Lau CB
    Biochem Pharmacol; 2017 Oct; 142():58-70. PubMed ID: 28669564
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular mechanism of endothelial nitric-oxide synthase activation by Platycodon grandiflorum root-derived saponins.
    Kim HG; Hien TT; Han EH; Chung YC; Jeong HG
    Toxicol Lett; 2010 Jun; 195(2-3):106-13. PubMed ID: 20230881
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
    Li JP; Yang YX; Liu QL; Pan ST; He ZX; Zhang X; Yang T; Chen XW; Wang D; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1627-52. PubMed ID: 25834401
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Piperlongumine induces apoptosis and autophagy in human lung cancer cells through inhibition of PI3K/Akt/mTOR pathway.
    Wang F; Mao Y; You Q; Hua D; Cai D
    Int J Immunopathol Pharmacol; 2015 Sep; 28(3):362-73. PubMed ID: 26246196
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lycorine Induces Apoptosis of A549 Cells via AMPK-Mammalian Target of Rapamycin (mTOR)-S6K Signaling Pathway.
    Zeng H; Fu R; Yan L; Huang J
    Med Sci Monit; 2017 Apr; 23():2035-2041. PubMed ID: 28450693
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.
    Wang F; Wang Q; Zhou ZW; Yu SN; Pan ST; He ZX; Zhang X; Wang D; Yang YX; Yang T; Sun T; Li M; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():537-60. PubMed ID: 25632222
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antiproliferative and apoptotic activities of triterpenoid saponins from the roots of Platycodon grandiflorum and their structure-activity relationships.
    Chun J; Ha IJ; Kim YS
    Planta Med; 2013 May; 79(8):639-45. PubMed ID: 23576176
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PDB-1 from Potentilla discolor Bunge induces apoptosis and autophagy by downregulating the PI3K/Akt/mTOR signaling pathway in A549 cells.
    Zhang RR; Meng NN; Liu C; Li KL; Wang MX; Lv ZB; Chen SY; Guo X; Wang XK; Wang Q; Sun JY
    Biomed Pharmacother; 2020 Sep; 129():110378. PubMed ID: 32544818
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antrodin C, an NADPH Dependent Metabolism, Encourages Crosstalk between Autophagy and Apoptosis in Lung Carcinoma Cells by Use of an AMPK Inhibition-Independent Blockade of the Akt/mTOR Pathway.
    Yang H; Bai X; Zhang H; Zhang J; Wu Y; Tang C; Liu Y; Yang Y; Liu Z; Jia W; Wang W
    Molecules; 2019 Mar; 24(5):. PubMed ID: 30870998
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Exploring the effects of different processing techniques on the composition and biological activity of Platycodon grandiflorus (Jacq.) A.DC. by metabonomics and pharmacologic design.
    Zhang Y; Zhang Y; Liang J; Kuang HX; Xia YG
    J Ethnopharmacol; 2022 May; 289():114991. PubMed ID: 35038566
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Coordinated time-dependent modulation of AMPK/Akt/mTOR signaling and autophagy controls osteogenic differentiation of human mesenchymal stem cells.
    Pantovic A; Krstic A; Janjetovic K; Kocic J; Harhaji-Trajkovic L; Bugarski D; Trajkovic V
    Bone; 2013 Jan; 52(1):524-31. PubMed ID: 23111315
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.