199 related articles for article (PubMed ID: 27993722)
1. Use of polymer conjugates for the intraperoxisomal delivery of engineered human alanine:glyoxylate aminotransferase as a protein therapy for primary hyperoxaluria type I.
Roncador A; Oppici E; Talelli M; Pariente AN; Donini M; Dusi S; Voltattorni CB; Vicent MJ; Cellini B
Nanomedicine; 2017 Apr; 13(3):897-907. PubMed ID: 27993722
[TBL] [Abstract][Full Text] [Related]
2. Enzymological and mutational analysis of a complex primary hyperoxaluria type 1 phenotype involving alanine:glyoxylate aminotransferase peroxisome-to-mitochondrion mistargeting and intraperoxisomal aggregation.
Danpure CJ; Purdue PE; Fryer P; Griffiths S; Allsop J; Lumb MJ; Guttridge KM; Jennings PR; Scheinman JI; Mauer SM
Am J Hum Genet; 1993 Aug; 53(2):417-32. PubMed ID: 8101040
[TBL] [Abstract][Full Text] [Related]
3. Primary hyperoxaluria type 1: AGT mistargeting highlights the fundamental differences between the peroxisomal and mitochondrial protein import pathways.
Danpure CJ
Biochim Biophys Acta; 2006 Dec; 1763(12):1776-84. PubMed ID: 17027096
[TBL] [Abstract][Full Text] [Related]
4. Gly161 mutations associated with Primary Hyperoxaluria Type I induce the cytosolic aggregation and the intracellular degradation of the apo-form of alanine:glyoxylate aminotransferase.
Oppici E; Roncador A; Montioli R; Bianconi S; Cellini B
Biochim Biophys Acta; 2013 Dec; 1832(12):2277-88. PubMed ID: 24055001
[TBL] [Abstract][Full Text] [Related]
5. Mammalian alanine/glyoxylate aminotransferase 1 is imported into peroxisomes via the PTS1 translocation pathway. Increased degeneracy and context specificity of the mammalian PTS1 motif and implications for the peroxisome-to-mitochondrion mistargeting of AGT in primary hyperoxaluria type 1.
Motley A; Lumb MJ; Oatey PB; Jennings PR; De Zoysa PA; Wanders RJ; Tabak HF; Danpure CJ
J Cell Biol; 1995 Oct; 131(1):95-109. PubMed ID: 7559790
[TBL] [Abstract][Full Text] [Related]
6. Pharmacologic rescue of an enzyme-trafficking defect in primary hyperoxaluria 1.
Miyata N; Steffen J; Johnson ME; Fargue S; Danpure CJ; Koehler CM
Proc Natl Acad Sci U S A; 2014 Oct; 111(40):14406-11. PubMed ID: 25237136
[TBL] [Abstract][Full Text] [Related]
7. Immunocytochemical localization of human hepatic alanine: glyoxylate aminotransferase in control subjects and patients with primary hyperoxaluria type 1.
Cooper PJ; Danpure CJ; Wise PJ; Guttridge KM
J Histochem Cytochem; 1988 Oct; 36(10):1285-94. PubMed ID: 3418107
[TBL] [Abstract][Full Text] [Related]
8. Correlation between the molecular effects of mutations at the dimer interface of alanine-glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B
Dindo M; Oppici E; Dell'Orco D; Montone R; Cellini B
J Inherit Metab Dis; 2018 Mar; 41(2):263-275. PubMed ID: 29110180
[TBL] [Abstract][Full Text] [Related]
9. Liver peroxisomal alanine:glyoxylate aminotransferase and the effects of mutations associated with Primary Hyperoxaluria Type I: An overview.
Oppici E; Montioli R; Cellini B
Biochim Biophys Acta; 2015 Sep; 1854(9):1212-9. PubMed ID: 25620715
[TBL] [Abstract][Full Text] [Related]
10. Pyridoxamine and pyridoxal are more effective than pyridoxine in rescuing folding-defective variants of human alanine:glyoxylate aminotransferase causing primary hyperoxaluria type I.
Oppici E; Fargue S; Reid ES; Mills PB; Clayton PT; Danpure CJ; Cellini B
Hum Mol Genet; 2015 Oct; 24(19):5500-11. PubMed ID: 26199318
[TBL] [Abstract][Full Text] [Related]
11. Effects of alanine:glyoxylate aminotransferase variants and pyridoxine sensitivity on oxalate metabolism in a cell-based cytotoxicity assay.
Fargue S; Knight J; Holmes RP; Rumsby G; Danpure CJ
Biochim Biophys Acta; 2016 Jun; 1862(6):1055-62. PubMed ID: 26854734
[TBL] [Abstract][Full Text] [Related]
12. Further studies on the activity and subcellular distribution of alanine:glyoxylate aminotransferase in the livers of patients with primary hyperoxaluria type 1.
Danpure CJ; Jennings PR
Clin Sci (Lond); 1988 Sep; 75(3):315-22. PubMed ID: 3416563
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of alanine:glyoxylate aminotransferase 1 dimerization is a prerequisite for its peroxisome-to-mitochondrion mistargeting in primary hyperoxaluria type 1.
Leiper JM; Oatey PB; Danpure CJ
J Cell Biol; 1996 Nov; 135(4):939-51. PubMed ID: 8922378
[TBL] [Abstract][Full Text] [Related]
14. Caenorhabditis elegans AGXT-1 is a mitochondrial and temperature-adapted ortholog of peroxisomal human AGT1: New insights into between-species divergence in glyoxylate metabolism.
Mesa-Torres N; Calvo AC; Oppici E; Titelbaum N; Montioli R; Miranda-Vizuete A; Cellini B; Salido E; Pey AL
Biochim Biophys Acta; 2016 Sep; 1864(9):1195-1205. PubMed ID: 27179589
[TBL] [Abstract][Full Text] [Related]
15. Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: implications for Primary Hyperoxaluria type 1.
Dindo M; Grottelli S; Annunziato G; Giardina G; Pieroni M; Pampalone G; Faccini A; CutruzzolĂ F; Laurino P; Costantino G; Cellini B
Biochem J; 2019 Dec; 476(24):3751-3768. PubMed ID: 31794008
[TBL] [Abstract][Full Text] [Related]
16. Oxalate synthesis in mammals: properties and subcellular distribution of serine:pyruvate/alanine:glyoxylate aminotransferase in the liver.
Ichiyama A; Xue HH; Oda T; Uchida C; Sugiyama T; Maeda-Nakai E; Sato K; Nagai E; Watanabe S; Takayama T
Mol Urol; 2000; 4(4):333-40. PubMed ID: 11156700
[TBL] [Abstract][Full Text] [Related]
17. Molecular Insight into the Synergism between the Minor Allele of Human Liver Peroxisomal Alanine:Glyoxylate Aminotransferase and the F152I Mutation.
Cellini B; Montioli R; Paiardini A; Lorenzetto A; Voltattorni CB
J Biol Chem; 2009 Mar; 284(13):8349-58. PubMed ID: 19155213
[TBL] [Abstract][Full Text] [Related]
18. The molecular basis of alanine: glyoxylate aminotransferase mistargeting: the most common single cause of primary hyperoxaluria type 1.
Danpure CJ
J Nephrol; 1998; 11 Suppl 1():8-12. PubMed ID: 9604801
[TBL] [Abstract][Full Text] [Related]
19. Systemic Alanine Glyoxylate Aminotransferase mRNA Improves Glyoxylate Metabolism in a Mouse Model of Primary Hyperoxaluria Type 1.
Kukreja A; Lasaro M; Cobaugh C; Forbes C; Tang JP; Gao X; Martin-Higueras C; Pey AL; Salido E; Sobolov S; Subramanian RR
Nucleic Acid Ther; 2019 Apr; 29(2):104-113. PubMed ID: 30676254
[TBL] [Abstract][Full Text] [Related]
20. Translation inhibition corrects aberrant localization of mutant alanine-glyoxylate aminotransferase: possible therapeutic approach for hyperoxaluria.
Belostotsky R; Lyakhovetsky R; Sherman MY; Shkedy F; Tzvi-Behr S; Bar R; Hoppe B; Reusch B; Beck BB; Frishberg Y
J Mol Med (Berl); 2018 Jul; 96(7):621-630. PubMed ID: 29777253
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]