BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 27993895)

  • 1. Mutation patterns in small cell and non-small cell lung cancer patients suggest a different level of heterogeneity between primary and metastatic tumors.
    Saber A; Hiltermann TJN; Kok K; Terpstra MM; de Lange K; Timens W; Groen HJM; van den Berg A
    Carcinogenesis; 2017 Feb; 38(2):144-151. PubMed ID: 27993895
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Multiregion sequencing reveals the intratumor heterogeneity of driver mutations in TP53-driven non-small cell lung cancer.
    Zhang LL; Kan M; Zhang MM; Yu SS; Xie HJ; Gu ZH; Wang HN; Zhao SX; Zhou GB; Song HD; Zheng CX
    Int J Cancer; 2017 Jan; 140(1):103-108. PubMed ID: 27646734
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients.
    Dietz S; Schirmer U; Mercé C; von Bubnoff N; Dahl E; Meister M; Muley T; Thomas M; Sültmann H
    PLoS One; 2016; 11(8):e0161012. PubMed ID: 27529345
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Multi-region exome sequencing reveals the intratumoral heterogeneity of surgically resected small cell lung cancer.
    Zhou H; Hu Y; Luo R; Zhao Y; Pan H; Ji L; Zhou T; Zhang L; Long H; Fu J; Wen Z; Wang S; Wang X; Lin P; Yang H; Wang J; Song M; Yi X; Yang L; Xia X; Guan Y; Fang W; Yang Y; Hong S; Huang Y; Li P; Zhang Y; Zhou N
    Nat Commun; 2021 Sep; 12(1):5431. PubMed ID: 34521849
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Detection of ubiquitous and heterogeneous mutations in cell-free DNA from patients with early-stage non-small-cell lung cancer.
    Jamal-Hanjani M; Wilson GA; Horswell S; Mitter R; Sakarya O; Constantin T; Salari R; Kirkizlar E; Sigurjonsson S; Pelham R; Kareht S; Zimmermann B; Swanton C
    Ann Oncol; 2016 May; 27(5):862-7. PubMed ID: 26823523
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Survivin expression impacts prognostically on NSCLC but not SCLC.
    Rosato A; Menin C; Boldrin D; Dalla Santa S; Bonaldi L; Scaini MC; Del Bianco P; Zardo D; Fassan M; Cappellesso R; Fassina A
    Lung Cancer; 2013 Feb; 79(2):180-6. PubMed ID: 23218791
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer.
    Liu Y; Kheradmand F; Davis CF; Scheurer ME; Wheeler D; Tsavachidis S; Armstrong G; Simpson C; Mandal D; Kupert E; Anderson M; You M; Xiong D; Pikielny C; Schwartz AG; Bailey-Wilson J; Gaba C; De Andrade M; Yang P; Pinney SM; ; Amos CI; Spitz MR
    J Thorac Oncol; 2016 Jan; 11(1):52-61. PubMed ID: 26762739
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Variable Intra-Tumor Genomic Heterogeneity of Multiple Lesions in Patients With Hepatocellular Carcinoma.
    Xue R; Li R; Guo H; Guo L; Su Z; Ni X; Qi L; Zhang T; Li Q; Zhang Z; Xie XS; Bai F; Zhang N
    Gastroenterology; 2016 Apr; 150(4):998-1008. PubMed ID: 26752112
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular subtyping of small-cell lung cancer based on mutational signatures with different genomic features and therapeutic strategies.
    Wang H; Wu S; Li Z; Zhang C; Shang X; Zhao C; Li Z; Lin J; Guo J; Wang Z
    Cancer Sci; 2023 Feb; 114(2):665-679. PubMed ID: 36178064
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance).
    Augert A; Zhang Q; Bates B; Cui M; Wang X; Wildey G; Dowlati A; MacPherson D
    J Thorac Oncol; 2017 Apr; 12(4):704-713. PubMed ID: 28007623
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Subclonal Genomic Architectures of Primary and Metastatic Colorectal Cancer Based on Intratumoral Genetic Heterogeneity.
    Kim TM; Jung SH; An CH; Lee SH; Baek IP; Kim MS; Park SW; Rhee JK; Lee SH; Chung YJ
    Clin Cancer Res; 2015 Oct; 21(19):4461-72. PubMed ID: 25979483
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents.
    Gao Q; Wang ZC; Duan M; Lin YH; Zhou XY; Worthley DL; Wang XY; Niu G; Xia Y; Deng M; Liu LZ; Shi JY; Yang LX; Zhang S; Ding ZB; Zhou J; Liang CM; Cao Y; Xiong L; Xi R; Shi YY; Fan J
    Gastroenterology; 2017 Jan; 152(1):232-242.e4. PubMed ID: 27639803
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Multiscale heterogeneity in gastric adenocarcinoma evolution is an obstacle to precision medicine.
    Röcken C; Amallraja A; Halske C; Opasic L; Traulsen A; Behrens HM; Krüger S; Liu A; Haag J; Egberts JH; Rosenstiel P; Meißner T
    Genome Med; 2021 Nov; 13(1):177. PubMed ID: 34749812
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer.
    Leong TL; Gayevskiy V; Steinfort DP; De Massy MR; Gonzalez-Rajal A; Marini KD; Stone E; Chin V; Havryk A; Plit M; Irving LB; Jennings BR; McCloy RA; Jayasekara WSN; Alamgeer M; Boolell V; Field A; Russell PA; Kumar B; Gough DJ; Szczepny A; Ganju V; Rossello FJ; Cain JE; Papenfuss AT; Asselin-Labat ML; Cowley MJ; Watkins DN
    Oncogene; 2019 Mar; 38(10):1661-1675. PubMed ID: 30348992
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Implementing amplicon-based next generation sequencing in the diagnosis of small cell lung carcinoma metastases.
    Meder L; König K; Fassunke J; Ozretić L; Wolf J; Merkelbach-Bruse S; Heukamp LC; Buettner R
    Exp Mol Pathol; 2015 Dec; 99(3):682-6. PubMed ID: 26546837
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Intratumoral heterogeneity of KRAS mutation is rare in non-small-cell lung cancer.
    Alsdorf WH; Clauditz TS; Hoenig T; Quaas A; Sirma H; Koenig AM; Izbicki J; Sauter G; Marx AH; Grob TJ
    Exp Mol Pathol; 2013 Feb; 94(1):155-9. PubMed ID: 23022742
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors.
    Wang D; Pham NA; Tong J; Sakashita S; Allo G; Kim L; Yanagawa N; Raghavan V; Wei Y; To C; Trinh QM; Starmans MH; Chan-Seng-Yue MA; Chadwick D; Li L; Zhu CQ; Liu N; Li M; Lee S; Ignatchenko V; Strumpf D; Taylor P; Moghal N; Liu G; Boutros PC; Kislinger T; Pintilie M; Jurisica I; Shepherd FA; McPherson JD; Muthuswamy L; Moran MF; Tsao MS
    Int J Cancer; 2017 Feb; 140(3):662-673. PubMed ID: 27750381
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Using whole genome amplification (WGA) of low-volume biopsies to assess the prognostic role of EGFR, KRAS, p53, and CMET mutations in advanced-stage non-small cell lung cancer (NSCLC).
    Lim EH; Zhang SL; Li JL; Yap WS; Howe TC; Tan BP; Lee YS; Wong D; Khoo KL; Seto KY; Tan L; Agasthian T; Koong HN; Tam J; Tan C; Caleb M; Chang A; Ng A; Tan P
    J Thorac Oncol; 2009 Jan; 4(1):12-21. PubMed ID: 19096301
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PIK3CA mutations in non-small cell lung cancer (NSCLC): genetic heterogeneity, prognostic impact and incidence of prior malignancies.
    Scheffler M; Bos M; Gardizi M; König K; Michels S; Fassunke J; Heydt C; Künstlinger H; Ihle M; Ueckeroth F; Albus K; Serke M; Gerigk U; Schulte W; Töpelt K; Nogova L; Zander T; Engel-Riedel W; Stoelben E; Ko YD; Randerath W; Kaminsky B; Panse J; Becker C; Hellmich M; Merkelbach-Bruse S; Heukamp LC; Büttner R; Wolf J
    Oncotarget; 2015 Jan; 6(2):1315-26. PubMed ID: 25473901
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer.
    Nong J; Gong Y; Guan Y; Yi X; Yi Y; Chang L; Yang L; Lv J; Guo Z; Jia H; Chu Y; Liu T; Chen M; Byers L; Roarty E; Lam VK; Papadimitrakopoulou VA; Wistuba I; Heymach JV; Glisson B; Liao Z; Lee JJ; Futreal PA; Zhang S; Xia X; Zhang J; Wang J
    Nat Commun; 2018 Aug; 9(1):3114. PubMed ID: 30082701
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.