525 related articles for article (PubMed ID: 27994519)
1. Anticancer Effects of a New SIRT Inhibitor, MHY2256, against Human Breast Cancer MCF-7 Cells via Regulation of MDM2-p53 Binding.
Park EY; Woo Y; Kim SJ; Kim DH; Lee EK; De U; Kim KS; Lee J; Jung JH; Ha KT; Choi WS; Kim IS; Lee BM; Yoon S; Moon HR; Kim HS
Int J Biol Sci; 2016; 12(12):1555-1567. PubMed ID: 27994519
[TBL] [Abstract][Full Text] [Related]
2. A New Synthetic Histone Deacetylase Inhibitor, MHY2256, Induces Apoptosis and Autophagy Cell Death in Endometrial Cancer Cells via p53 Acetylation.
De U; Son JY; Sachan R; Park YJ; Kang D; Yoon K; Lee BM; Kim IS; Moon HR; Kim HS
Int J Mol Sci; 2018 Sep; 19(9):. PubMed ID: 30217020
[TBL] [Abstract][Full Text] [Related]
3. Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells.
Wang J; Kim TH; Ahn MY; Lee J; Jung JH; Choi WS; Lee BM; Yoon KS; Yoon S; Kim HS
Int J Oncol; 2012 Sep; 41(3):1101-9. PubMed ID: 22751989
[TBL] [Abstract][Full Text] [Related]
4. Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts.
Kim TH; Kim HS; Kang YJ; Yoon S; Lee J; Choi WS; Jung JH; Kim HS
Biochim Biophys Acta; 2015 Feb; 1850(2):401-10. PubMed ID: 25445714
[TBL] [Abstract][Full Text] [Related]
5. Spiro-oxindole derivative 5-chloro-4',5'-diphenyl-3'-(4-(2-(piperidin-1-yl) ethoxy) benzoyl) spiro[indoline-3,2'-pyrrolidin]-2-one triggers apoptosis in breast cancer cells via restoration of p53 function.
Saxena R; Gupta G; Manohar M; Debnath U; Popli P; Prabhakar YS; Konwar R; Kumar S; Kumar A; Dwivedi A
Int J Biochem Cell Biol; 2016 Jan; 70():105-17. PubMed ID: 26556313
[TBL] [Abstract][Full Text] [Related]
6. Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation.
Qin JJ; Wang W; Voruganti S; Wang H; Zhang WD; Zhang R
Oncotarget; 2015 Feb; 6(5):2623-40. PubMed ID: 25739118
[TBL] [Abstract][Full Text] [Related]
7. A novel all-trans retinoic acid derivative 4-amino‑2‑trifluoromethyl-phenyl retinate inhibits the proliferation of human hepatocellular carcinoma HepG2 cells by inducing G0/G1 cell cycle arrest and apoptosis via upregulation of p53 and ASPP1 and downregulation of iASPP.
Liu H; Chen F; Zhang L; Zhou Q; Gui S; Wang Y
Oncol Rep; 2016 Jul; 36(1):333-41. PubMed ID: 27177208
[TBL] [Abstract][Full Text] [Related]
8. SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2.
Peck B; Chen CY; Ho KK; Di Fruscia P; Myatt SS; Coombes RC; Fuchter MJ; Hsiao CD; Lam EW
Mol Cancer Ther; 2010 Apr; 9(4):844-55. PubMed ID: 20371709
[TBL] [Abstract][Full Text] [Related]
9. Plumbagin from a tropical pitcher plant (Nepenthes alata Blanco) induces apoptotic cell death via a p53-dependent pathway in MCF-7 human breast cancer cells.
De U; Son JY; Jeon Y; Ha SY; Park YJ; Yoon S; Ha KT; Choi WS; Lee BM; Kim IS; Kwak JH; Kim HS
Food Chem Toxicol; 2019 Jan; 123():492-500. PubMed ID: 30458268
[TBL] [Abstract][Full Text] [Related]
10. A new synthetic HDAC inhibitor, MHY218, induces apoptosis or autophagy-related cell death in tamoxifen-resistant MCF-7 breast cancer cells.
Park JH; Ahn MY; Kim TH; Yoon S; Kang KW; Lee J; Moon HR; Jung JH; Chung HY; Kim HS
Invest New Drugs; 2012 Oct; 30(5):1887-98. PubMed ID: 21983700
[TBL] [Abstract][Full Text] [Related]
11. Inhibiting MDM2-p53 Interaction Suppresses Tumor Growth in Patient-Derived Non-Small Cell Lung Cancer Xenograft Models.
Hai J; Sakashita S; Allo G; Ludkovski O; Ng C; Shepherd FA; Tsao MS
J Thorac Oncol; 2015 Aug; 10(8):1172-80. PubMed ID: 26200271
[TBL] [Abstract][Full Text] [Related]
12. Violacein induces apoptosis in human breast cancer cells through up regulation of BAX, p53 and down regulation of MDM2.
Alshatwi AA; Subash-Babu P; Antonisamy P
Exp Toxicol Pathol; 2016 Jan; 68(1):89-97. PubMed ID: 26521020
[TBL] [Abstract][Full Text] [Related]
13. DIMP53-1: a novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer properties.
Soares J; Espadinha M; Raimundo L; Ramos H; Gomes AS; Gomes S; Loureiro JB; Inga A; Reis F; Gomes C; Santos MMM; Saraiva L
Mol Oncol; 2017 Jun; 11(6):612-627. PubMed ID: 28296148
[TBL] [Abstract][Full Text] [Related]
14. Melatonin down-regulates MDM2 gene expression and enhances p53 acetylation in MCF-7 cells.
Proietti S; Cucina A; Dobrowolny G; D'Anselmi F; Dinicola S; Masiello MG; Pasqualato A; Palombo A; Morini V; Reiter RJ; Bizzarri M
J Pineal Res; 2014 Aug; 57(1):120-9. PubMed ID: 24920214
[TBL] [Abstract][Full Text] [Related]
15. Novel SIRT Inhibitor, MHY2256, Induces Cell Cycle Arrest, Apoptosis, and Autophagic Cell Death in HCT116 Human Colorectal Cancer Cells.
Kim MJ; Kang YJ; Sung B; Jang JY; Ahn YR; Oh HJ; Choi H; Choi I; Im E; Moon HR; Chung HY; Kim ND
Biomol Ther (Seoul); 2020 Nov; 28(6):561-568. PubMed ID: 33073770
[TBL] [Abstract][Full Text] [Related]
16. Induction of p53 expression and apoptosis by a recombinant dual-target MDM2/MDMX inhibitory protein in wild-type p53 breast cancer cells.
Geng QQ; Dong DF; Chen NZ; Wu YY; Li EX; Wang J; Wang SM
Int J Oncol; 2013 Dec; 43(6):1935-42. PubMed ID: 24126697
[TBL] [Abstract][Full Text] [Related]
17. MDM2 small-molecule antagonist RG7112 activates p53 signaling and regresses human tumors in preclinical cancer models.
Tovar C; Graves B; Packman K; Filipovic Z; Higgins B; Xia M; Tardell C; Garrido R; Lee E; Kolinsky K; To KH; Linn M; Podlaski F; Wovkulich P; Vu B; Vassilev LT
Cancer Res; 2013 Apr; 73(8):2587-97. PubMed ID: 23400593
[TBL] [Abstract][Full Text] [Related]
18. Efficacy of MDM2 inhibitor MI-219 against lung cancer cells alone or in combination with MDM2 knockdown, a XIAP inhibitor or etoposide.
Zheng M; Yang J; Xu X; Sebolt JT; Wang S; Sun Y
Anticancer Res; 2010 Sep; 30(9):3321-31. PubMed ID: 20944104
[TBL] [Abstract][Full Text] [Related]
19. 2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol inhibits MDM2 and induces apoptosis in breast cancer cells through a p53-independent pathway.
Xu J; Han M; Shen J; Guan Q; Bai Z; Lang B; Zhang H; Li Z; Zuo D; Zhang W; Wu Y
Cancer Lett; 2016 Dec; 383(1):9-17. PubMed ID: 27693458
[TBL] [Abstract][Full Text] [Related]
20. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
Li JP; Yang YX; Liu QL; Pan ST; He ZX; Zhang X; Yang T; Chen XW; Wang D; Qiu JX; Zhou SF
Drug Des Devel Ther; 2015; 9():1627-52. PubMed ID: 25834401
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
