BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 27994737)

  • 1. Scaffold-Hopping of Aurones: 2-Arylideneimidazo[1,2-
    Priyadarshani G; Nayak A; Amrutkar SM; Das S; Guchhait SK; Kundu CN; Banerjee UC
    ACS Med Chem Lett; 2016 Dec; 7(12):1056-1061. PubMed ID: 27994737
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Scaffold-hopping of bioactive flavonoids: Discovery of aryl-pyridopyrimidinones as potent anticancer agents that inhibit catalytic role of topoisomerase IIα.
    Priyadarshani G; Amrutkar S; Nayak A; Banerjee UC; Kundu CN; Guchhait SK
    Eur J Med Chem; 2016 Oct; 122():43-54. PubMed ID: 27343852
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Organocatalyzed umpolung addition for synthesis of heterocyclic-fused arylidene-imidazolones as anticancer agents.
    Kumar G; Das C; Acharya A; Bhal S; Joshi M; Kundu CN; Choudhury AR; Guchhait SK
    Bioorg Med Chem; 2022 Aug; 67():116835. PubMed ID: 35617791
    [TBL] [Abstract][Full Text] [Related]  

  • 4. N-fused imidazoles as novel anticancer agents that inhibit catalytic activity of topoisomerase IIα and induce apoptosis in G1/S phase.
    Baviskar AT; Madaan C; Preet R; Mohapatra P; Jain V; Agarwal A; Guchhait SK; Kundu CN; Banerjee UC; Bharatam PV
    J Med Chem; 2011 Jul; 54(14):5013-30. PubMed ID: 21644529
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacoinformatics analysis of merbarone binding site in human topoisomerase IIα.
    Tripathi N; Guchhait SK; Bharatam PV
    J Mol Graph Model; 2019 Jan; 86():1-18. PubMed ID: 30296751
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and SAR study of new hydroxy and chloro-substituted 2,4-diphenyl 5H-chromeno[4,3-b]pyridines as selective topoisomerase IIα-targeting anticancer agents.
    Magar TBT; Seo SH; Kadayat TM; Jo H; Shrestha A; Bist G; Katila P; Kwon Y; Lee ES
    Bioorg Med Chem; 2018 May; 26(8):1909-1919. PubMed ID: 29510948
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Switch in Site of Inhibition: A Strategy for Structure-Based Discovery of Human Topoisomerase IIα Catalytic Inhibitors.
    Baviskar AT; Amrutkar SM; Trivedi N; Chaudhary V; Nayak A; Guchhait SK; Banerjee UC; Bharatam PV; Kundu CN
    ACS Med Chem Lett; 2015 Apr; 6(4):481-5. PubMed ID: 25941559
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dihydroxylated 2,6-diphenyl-4-chlorophenylpyridines: Topoisomerase I and IIα dual inhibitors with DNA non-intercalative catalytic activity.
    Bist G; Park S; Song C; Thapa Magar TB; Shrestha A; Kwon Y; Lee ES
    Eur J Med Chem; 2017 Jun; 133():69-84. PubMed ID: 28384547
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of C1-O-substituted-3-(3-butylamino-2-hydroxy-propoxy)-xanthen-9-one as topoisomerase IIα catalytic inhibitors.
    Park S; Hong E; Kwak SY; Jun KY; Lee ES; Kwon Y; Na Y
    Eur J Med Chem; 2016 Nov; 123():211-225. PubMed ID: 27484510
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel 2-aryl-4-(4'-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors.
    Park S; Kadayat TM; Jun KY; Thapa Magar TB; Bist G; Shrestha A; Lee ES; Kwon Y
    Eur J Med Chem; 2017 Jan; 125():14-28. PubMed ID: 27643560
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of N-(carbobenzyloxy)-l-phenylalanine and N-(carbobenzyloxy)-l-aspartic acid-β-benzyl ester derivatives as potent topoisomerase IIα inhibitors.
    Han X; Zhong Y; Zhou G; Qi H; Li S; Ding Q; Liu Z; Song Y; Qiao X
    Bioorg Med Chem; 2017 Jun; 25(12):3116-3126. PubMed ID: 28462840
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and synthesis of 2-phenylnaphthalenoids and 2-phenylbenzofuranoids as DNA topoisomerase inhibitors and antitumor agents.
    Hao H; Chen W; Zhu J; Lu C; Shen Y
    Eur J Med Chem; 2015 Sep; 102():277-87. PubMed ID: 26291037
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Scaffold-Hopping Strategies in Aurone Optimization: A Comprehensive Review of Synthetic Procedures and Biological Activities of Nitrogen and Sulfur Analogues.
    La Monica G; Alamia F; Bono A; Lauria A; Martorana A
    Molecules; 2024 Jun; 29(12):. PubMed ID: 38930878
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Adenovirus-mediated human topoisomerase IIalpha gene transfer increases the sensitivity of etoposide-resistant human breast cancer cells.
    Zhou Z; Zwelling LA; Kawakami Y; An T; Kobayashi K; Herzog C; Kleinerman ES
    Cancer Res; 1999 Sep; 59(18):4618-24. PubMed ID: 10493516
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bioassays and In Silico Methods in the Identification of Human DNA Topoisomerase IIα Inhibitors.
    Bergant K; Janezic M; Perdih A
    Curr Med Chem; 2018; 25(28):3286-3318. PubMed ID: 29508675
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors.
    Arepalli SK; Lee C; Sim S; Lee K; Jo H; Jun KY; Kwon Y; Kang JS; Jung JK; Lee H
    Bioorg Med Chem; 2018 Oct; 26(18):5181-5193. PubMed ID: 30253887
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Salvicine functions as novel topoisomerase II poison by binding to ATP pocket.
    Hu CX; Zuo ZL; Xiong B; Ma JG; Geng MY; Lin LP; Jiang HL; Ding J
    Mol Pharmacol; 2006 Nov; 70(5):1593-601. PubMed ID: 16914642
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of Topoisomerase IIα and Induction of Apoptosis in Gastric Cancer Cells by 19-Triisopropyl Andrographolide.
    Monger A; Boonmuen N; Suksen K; Saeeng R; Kasemsuk T; Piyachaturawat P; Saengsawang W; Chairoungdua A
    Asian Pac J Cancer Prev; 2017 Oct; 18(10):2845-2851. PubMed ID: 29072435
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A three-dimensional quantitative structure-activity relationship study of the inhibition of the ATPase activity and the strand passing catalytic activity of topoisomerase IIalpha by substituted purine analogs.
    Jensen LH; Liang H; Shoemaker R; Grauslund M; Sehested M; Hasinoff BB
    Mol Pharmacol; 2006 Nov; 70(5):1503-13. PubMed ID: 16880287
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HToPred: A Tool for Human Topoisomerase II Inhibitor Prediction.
    Tripathi N; Shaikh N; Bharatam PV; Garg P
    Mol Inform; 2019 Jan; 38(1-2):e1800046. PubMed ID: 30216700
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.