BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 27995250)

  • 21. Zoning in on Tankyrases: A Brief Review on the Past, Present and Prospective Studies.
    Peters XQ; Malinga TH; Agoni C; Olotu FA; Soliman MES
    Anticancer Agents Med Chem; 2019; 19(16):1920-1934. PubMed ID: 31648650
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Tankyrase inhibition sensitizes cells to CDK4 blockade.
    Foronda M; Tarumoto Y; Schatoff EM; Leach BI; Diaz BJ; Zimmerman J; Goswami S; Shusterman M; Vakoc CR; Dow LE
    PLoS One; 2019; 14(12):e0226645. PubMed ID: 31891587
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Exploration of the structural requirements of HIV-protease inhibitors using pharmacophore, virtual screening and molecular docking approaches for lead identification.
    Islam MA; Pillay TS
    J Mol Graph Model; 2015 Mar; 56():20-30. PubMed ID: 25541527
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Identification of novel phosphodiesterase-4D inhibitors prescreened by molecular dynamics-augmented modeling and validated by bioassay.
    Li Z; Cai YH; Cheng YK; Lu X; Shao YX; Li X; Liu M; Liu P; Luo HB
    J Chem Inf Model; 2013 Apr; 53(4):972-81. PubMed ID: 23517293
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Structural basis of selective inhibition of human tankyrases.
    Narwal M; Venkannagari H; Lehtiö L
    J Med Chem; 2012 Feb; 55(3):1360-7. PubMed ID: 22233320
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Virtual screening of small molecules databases for discovery of novel PARP-1 inhibitors: combination of in silico and in vitro studies.
    Ekhteiari Salmas R; Unlu A; Bektaş M; Yurtsever M; Mestanoglu M; Durdagi S
    J Biomol Struct Dyn; 2017 Jul; 35(9):1899-1915. PubMed ID: 27315035
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Multiple receptor-ligand based pharmacophore modeling and molecular docking to screen the selective inhibitors of matrix metalloproteinase-9 from natural products.
    Gao Q; Wang Y; Hou J; Yao Q; Zhang J
    J Comput Aided Mol Des; 2017 Jul; 31(7):625-641. PubMed ID: 28623487
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Molecular dynamics-based discovery of novel phosphodiesterase-9A inhibitors with non-pyrazolopyrimidinone scaffolds.
    Li Z; Lu X; Feng LJ; Gu Y; Li X; Wu Y; Luo HB
    Mol Biosyst; 2015 Jan; 11(1):115-25. PubMed ID: 25328054
    [TBL] [Abstract][Full Text] [Related]  

  • 29. [1,2,4]triazol-3-ylsulfanylmethyl)-3-phenyl-[1,2,4]oxadiazoles: antagonists of the Wnt pathway that inhibit tankyrases 1 and 2 via novel adenosine pocket binding.
    Shultz MD; Kirby CA; Stams T; Chin DN; Blank J; Charlat O; Cheng H; Cheung A; Cong F; Feng Y; Fortin PD; Hood T; Tyagi V; Xu M; Zhang B; Shao W
    J Med Chem; 2012 Feb; 55(3):1127-36. PubMed ID: 22260203
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Tankyrase as a Novel Molecular Target in Cancer and Fibrotic Diseases.
    Lakshmi TV; Bale S; Khurana A; Godugu C
    Curr Drug Targets; 2017; 18(10):1214-1224. PubMed ID: 27425647
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The binding mechanism of a novel nicotinamide isostere inhibiting with TNKSs: a molecular dynamic simulation and binding free energy calculation.
    Feng TT; Zhang YJ; Chen H; Fan S; Han JG
    J Biomol Struct Dyn; 2016; 34(3):517-28. PubMed ID: 25933061
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Probing PARP1-inhibitor complexes for the development of novel inhibitors.
    Saqib U; Baig MS
    Cell Mol Biol (Noisy-le-grand); 2014 Oct; 60(3):43-52. PubMed ID: 25346248
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Unravelling the Structural Mechanism of Action of 5-methyl-5-[4-(4-oxo-3H-quinazolin-2-yl)phenyl]imidazolidine-2,4-dione in Dual-Targeting Tankyrase 1 and 2: A Novel Avenue in Cancer Therapy.
    Peters XQ; Agoni C; Soliman MES
    Cell Biochem Biophys; 2022 Sep; 80(3):505-518. PubMed ID: 35637423
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Identification of potential dual agonists of FXR and TGR5 using e-pharmacophore based virtual screening.
    Sindhu T; Srinivasan P
    Mol Biosyst; 2015 May; 11(5):1305-18. PubMed ID: 25787676
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Fragment-based ligand design of novel potent inhibitors of tankyrases.
    Larsson EA; Jansson A; Ng FM; Then SW; Panicker R; Liu B; Sangthongpitag K; Pendharkar V; Tai SJ; Hill J; Dan C; Ho SY; Cheong WW; Poulsen A; Blanchard S; Lin GR; Alam J; Keller TH; Nordlund P
    J Med Chem; 2013 Jun; 56(11):4497-508. PubMed ID: 23672613
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Insights of tankyrases: A novel target for drug discovery.
    Damale MG; Pathan SK; Shinde DB; Patil RH; Arote RB; Sangshetti JN
    Eur J Med Chem; 2020 Dec; 207():112712. PubMed ID: 32877803
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors.
    Shirai F; Tsumura T; Yashiroda Y; Yuki H; Niwa H; Sato S; Chikada T; Koda Y; Washizuka K; Yoshimoto N; Abe M; Onuki T; Mazaki Y; Hirama C; Fukami T; Watanabe H; Honma T; Umehara T; Shirouzu M; Okue M; Kano Y; Watanabe T; Kitamura K; Shitara E; Muramatsu Y; Yoshida H; Mizutani A; Seimiya H; Yoshida M; Koyama H
    J Med Chem; 2019 Apr; 62(7):3407-3427. PubMed ID: 30883102
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Identification of InhA inhibitors: A combination of virtual screening, molecular dynamics simulations and quantum chemical studies.
    Lone MY; Manhas A; Athar M; Jha PC
    J Biomol Struct Dyn; 2018 Aug; 36(11):2951-2965. PubMed ID: 28849732
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach.
    Anumala UR; Waaler J; Nkizinkiko Y; Ignatev A; Lazarow K; Lindemann P; Olsen PA; Murthy S; Obaji E; Majouga AG; Leonov S; von Kries JP; Lehtiö L; Krauss S; Nazaré M
    J Med Chem; 2017 Dec; 60(24):10013-10025. PubMed ID: 29155568
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Molecular dynamics and integrated pharmacophore-based identification of dual [Formula: see text] inhibitors.
    Kaur M; Singh PK; Singh M; Bahadur R; Silakari O
    Mol Divers; 2018 Feb; 22(1):95-112. PubMed ID: 29138965
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.