BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 28000361)

  • 1. Cyclopropane-Based Peptidomimetics Mimicking Wide-Ranging Secondary Structures of Peptides: Conformational Analysis and Their Use in Rational Ligand Optimization.
    Mizuno A; Kameda T; Kuwahara T; Endoh H; Ito Y; Yamada S; Hasegawa K; Yamano A; Watanabe M; Arisawa M; Shuto S
    Chemistry; 2017 Mar; 23(13):3159-3168. PubMed ID: 28000361
    [TBL] [Abstract][Full Text] [Related]  

  • 2. From Peptides to Peptidomimetics: A Strategy Based on the Structural Features of Cyclopropane.
    Mizuno A; Matsui K; Shuto S
    Chemistry; 2017 Oct; 23(58):14394-14409. PubMed ID: 28632330
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Three-dimensional structural diversity-oriented peptidomimetics based on the cyclopropylic strain.
    Mizuno A; Miura S; Watanabe M; Ito Y; Yamada S; Odagami T; Kogami Y; Arisawa M; Shuto S
    Org Lett; 2013 Apr; 15(7):1686-9. PubMed ID: 23528142
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cyclopropane-derived peptidomimetics. Design, synthesis, evaluation, and structure of novel HIV-1 protease inhibitors.
    Martin SF; Dorsey GO; Gane T; Hillier MC; Kessler H; Baur M; Mathä B; Erickson JW; Bhat TN; Munshi S; Gulnik SV; Topol IA
    J Med Chem; 1998 May; 41(10):1581-97. PubMed ID: 9572884
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cyclopropane-based stereochemical diversity-oriented conformational restriction strategy: histamine H3 and/or H4 receptor ligands with the 2,3-methanobutane backbone.
    Watanabe M; Kobayashi T; Hirokawa T; Yoshida A; Ito Y; Yamada S; Orimoto N; Yamasaki Y; Arisawa M; Shuto S
    Org Biomol Chem; 2012 Jan; 10(4):736-45. PubMed ID: 22120611
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Incorporation of a bioactive reverse-turn heterocycle into a peptide template using solid-phase synthesis to probe melanocortin receptor selectivity and ligand conformations by 2D 1H NMR.
    Singh A; Wilczynski A; Holder JR; Witek RM; Dirain ML; Xiang Z; Edison AS; Haskell-Luevano C
    J Med Chem; 2011 Mar; 54(5):1379-90. PubMed ID: 21306168
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cyclic RGD peptidomimetics containing 4- and 5-amino-cyclopropane pipecolic acid (CPA) templates as dual αVβ3 and α5β1 integrin ligands.
    Sernissi L; Trabocchi A; Scarpi D; Bianchini F; Occhiato EG
    Bioorg Med Chem; 2016 Feb; 24(4):703-11. PubMed ID: 26753814
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pyrrolinone-based peptidomimetics. "Let the enzyme or receptor be the judge".
    Smith AB; Charnley AK; Hirschmann R
    Acc Chem Res; 2011 Mar; 44(3):180-93. PubMed ID: 21175156
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and properties of cyclopropane-derived peptidomimetics.
    Reichelt A; Martin SF
    Acc Chem Res; 2006 Jul; 39(7):433-42. PubMed ID: 16846207
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of Macrocyclic Peptidomimetics Containing Constrained α,α-Dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors.
    Merlino F; Zhou Y; Cai M; Carotenuto A; Yousif AM; Brancaccio D; Di Maro S; Zappavigna S; Limatola A; Novellino E; Grieco P; Hruby VJ
    J Med Chem; 2018 May; 61(9):4263-4269. PubMed ID: 29660981
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Highly Conformationally Restricted Cyclopropane Tethers with Three-Dimensional Structural Diversity Drastically Enhance the Cell Permeability of Cyclic Peptides.
    Matsui K; Kido Y; Watari R; Kashima Y; Yoshida Y; Shuto S
    Chemistry; 2017 Mar; 23(13):3034-3041. PubMed ID: 27878880
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A new class of peptidomimetics targeting the polo-box domain of Polo-like kinase 1.
    Ahn M; Han YH; Park JE; Kim S; Lee WC; Lee SJ; Gunasekaran P; Cheong C; Shin SY; Kim HY; Ryu EK; Murugan RN; Kim NH; Bang JK
    J Med Chem; 2015 Jan; 58(1):294-304. PubMed ID: 25347203
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Progress toward rationally designed small-molecule peptide and peptidomimetic CXCR4 antagonists.
    Våbenø J; Haug BE; Rosenkilde MM
    Future Med Chem; 2015; 7(10):1261-83. PubMed ID: 26144264
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Three-step synthesis of cyclopropyl peptidomimetics.
    Dunlap N; Lankford KR; Pathiranage AL; Taylor J; Reddy N; Gouger D; Singer P; Griffin K; Reibenspies J
    Org Lett; 2011 Sep; 13(18):4879-81. PubMed ID: 21863816
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Therapeutic peptides and peptidomimetics.
    Kieber-Emmons T; Murali R; Greene MI
    Curr Opin Biotechnol; 1997 Aug; 8(4):435-41. PubMed ID: 9265722
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Conformational analysis of the NMDA receptor antagonist (1S,2R)-1-phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC) designed by a novel conformational restriction method based on the structural feature of cyclopropane ring.
    Ono S; Ogawa K; Yamashita K; Yamamoto T; Kazuta Y; Matsuda A; Shuto S
    Chem Pharm Bull (Tokyo); 2002 Jul; 50(7):966-8. PubMed ID: 12130856
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclopropane pipecolic acids as templates for linear and cyclic peptidomimetics: application in the synthesis of an Arg-Gly-Asp (RGD)-containing peptide as an αvβ3 integrin ligand.
    Sernissi L; Petrović M; Scarpi D; Guarna A; Trabocchi A; Bianchini F; Occhiato EG
    Chemistry; 2014 Aug; 20(35):11187-203. PubMed ID: 25069617
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conformationally constrained histidines in the design of peptidomimetics: strategies for the χ-space control.
    Stefanucci A; Pinnen F; Feliciani F; Cacciatore I; Lucente G; Mollica A
    Int J Mol Sci; 2011; 12(5):2853-90. PubMed ID: 21686155
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rational Design of Calpain Inhibitors Based on Calpastatin Peptidomimetics.
    Low KE; Ler S; Chen KJ; Campbell RL; Hickey JL; Tan J; Scully CC; Davies PL; Yudin AK; Zaretsky S
    J Med Chem; 2016 Jun; 59(11):5403-15. PubMed ID: 27148623
    [TBL] [Abstract][Full Text] [Related]  

  • 20. β(3R3)-Peptides: design and synthesis of novel peptidomimetics and their self-assembling properties at the air-water interface.
    Mosca S; Dannehl C; Möginger U; Brezesinski G; Hartmann L
    Org Biomol Chem; 2013 Sep; 11(33):5399-403. PubMed ID: 23860843
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.