280 related articles for article (PubMed ID: 28000554)
1. A Homodimer Model Can Resolve the Conundrum as to How Cytochrome P450 Oxidoreductase and Cytochrome b5 Compete for the Same Binding Site on Cytochrome P450c17.
Holien JK; Parker MW; Conley AJ; Corbin CJ; Rodgers RJ; Martin LL
Curr Protein Pept Sci; 2017; 18(5):515-521. PubMed ID: 28000554
[TBL] [Abstract][Full Text] [Related]
2. Regulation of 17,20 lyase activity by cytochrome b5 and by serine phosphorylation of P450c17.
Pandey AV; Miller WL
J Biol Chem; 2005 Apr; 280(14):13265-71. PubMed ID: 15687493
[TBL] [Abstract][Full Text] [Related]
3. Assessment of the ability of type 2 cytochrome b5 to modulate 17,20-lyase activity of human P450c17.
Soucy P; Luu-The V
J Steroid Biochem Mol Biol; 2002 Jan; 80(1):71-5. PubMed ID: 11867265
[TBL] [Abstract][Full Text] [Related]
4. The primate adrenal zona reticularis is defined by expression of cytochrome b5, 17alpha-hydroxylase/17,20-lyase cytochrome P450 (P450c17) and NADPH-cytochrome P450 reductase (reductase) but not 3beta-hydroxysteroid dehydrogenase/delta5-4 isomerase (3beta-HSD).
Mapes S; Corbin CJ; Tarantal A; Conley A
J Clin Endocrinol Metab; 1999 Sep; 84(9):3382-5. PubMed ID: 10487714
[TBL] [Abstract][Full Text] [Related]
5. Role of cytochrome b5 in the modulation of the enzymatic activities of cytochrome P450 17α-hydroxylase/17,20-lyase (P450 17A1).
Bhatt MR; Khatri Y; Rodgers RJ; Martin LL
J Steroid Biochem Mol Biol; 2017 Jun; 170():2-18. PubMed ID: 26976652
[TBL] [Abstract][Full Text] [Related]
6. P450c17 mutations R347H and R358Q selectively disrupt 17,20-lyase activity by disrupting interactions with P450 oxidoreductase and cytochrome b5.
Geller DH; Auchus RJ; Miller WL
Mol Endocrinol; 1999 Jan; 13(1):167-75. PubMed ID: 9892022
[TBL] [Abstract][Full Text] [Related]
7. Substrate-modulated cytochrome P450 17A1 and cytochrome b5 interactions revealed by NMR.
Estrada DF; Laurence JS; Scott EE
J Biol Chem; 2013 Jun; 288(23):17008-17018. PubMed ID: 23620596
[TBL] [Abstract][Full Text] [Related]
8. NADPH-flavodoxin reductase and flavodoxin from Escherichia coli: characteristics as a soluble microsomal P450 reductase.
Jenkins CM; Waterman MR
Biochemistry; 1998 Apr; 37(17):6106-13. PubMed ID: 9558349
[TBL] [Abstract][Full Text] [Related]
9. Kinetic processivity of the two-step oxidations of progesterone and pregnenolone to androgens by human cytochrome P450 17A1.
Gonzalez E; Guengerich FP
J Biol Chem; 2017 Aug; 292(32):13168-13185. PubMed ID: 28684414
[TBL] [Abstract][Full Text] [Related]
10. Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1).
Simonov AN; Holien JK; Yeung JC; Nguyen AD; Corbin CJ; Zheng J; Kuznetsov VL; Auchus RJ; Conley AJ; Bond AM; Parker MW; Rodgers RJ; Martin LL
PLoS One; 2015; 10(11):e0141252. PubMed ID: 26587646
[TBL] [Abstract][Full Text] [Related]
11. Catalytically relevant electrostatic interactions of cytochrome P450c17 (CYP17A1) and cytochrome b5.
Peng HM; Liu J; Forsberg SE; Tran HT; Anderson SM; Auchus RJ
J Biol Chem; 2014 Dec; 289(49):33838-49. PubMed ID: 25315771
[TBL] [Abstract][Full Text] [Related]
12. Cytochrome b5 Activates the 17,20-Lyase Activity of Human Cytochrome P450 17A1 by Increasing the Coupling of NADPH Consumption to Androgen Production.
Peng HM; Im SC; Pearl NM; Turcu AF; Rege J; Waskell L; Auchus RJ
Biochemistry; 2016 Aug; 55(31):4356-65. PubMed ID: 27426448
[TBL] [Abstract][Full Text] [Related]
13. Regulation of cytochrome b5 gene transcription by Sp3, GATA-6, and steroidogenic factor 1 in human adrenal NCI-H295A cells.
Huang N; Dardis A; Miller WL
Mol Endocrinol; 2005 Aug; 19(8):2020-34. PubMed ID: 15831526
[TBL] [Abstract][Full Text] [Related]
14. Cytochrome P450c17 from porcine and bovine adrenal catalyses the formation of 5,16-androstadien-3 beta-ol from pregnenolone in the presence of cytochrome b5.
Meadus WJ; Mason JI; Squires EJ
J Steroid Biochem Mol Biol; 1993 Nov; 46(5):565-72. PubMed ID: 8240978
[TBL] [Abstract][Full Text] [Related]
15. Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer.
Auchus RJ; Lee TC; Miller WL
J Biol Chem; 1998 Feb; 273(6):3158-65. PubMed ID: 9452426
[TBL] [Abstract][Full Text] [Related]
16. Developmental changes in steroidogenic enzymes in human postnatal adrenal cortex: immunohistochemical studies.
Suzuki T; Sasano H; Takeyama J; Kaneko C; Freije WA; Carr BR; Rainey WE
Clin Endocrinol (Oxf); 2000 Dec; 53(6):739-47. PubMed ID: 11155097
[TBL] [Abstract][Full Text] [Related]
17. The regulation of 17,20 lyase activity.
Miller WL; Auchus RJ; Geller DH
Steroids; 1997 Jan; 62(1):133-42. PubMed ID: 9029728
[TBL] [Abstract][Full Text] [Related]
18. The developmental increase in adrenocortical 17,20-lyase activity (biochemical adrenarche) is driven primarily by increasing cytochrome b5 in neonatal rhesus macaques.
Nguyen AD; Corbin CJ; Pattison JC; Bird IM; Conley AJ
Endocrinology; 2009 Apr; 150(4):1748-56. PubMed ID: 19036885
[TBL] [Abstract][Full Text] [Related]
19. Biochemical differences between rat and human cytochrome P450c17 support the different steroidogenic needs of these two species.
Brock BJ; Waterman MR
Biochemistry; 1999 Feb; 38(5):1598-606. PubMed ID: 9931027
[TBL] [Abstract][Full Text] [Related]
20. Organization of cytochrome P450 enzymes involved in sex steroid synthesis: PROTEIN-PROTEIN INTERACTIONS IN LIPID MEMBRANES.
Praporski S; Ng SM; Nguyen AD; Corbin CJ; Mechler A; Zheng J; Conley AJ; Martin LL
J Biol Chem; 2009 Nov; 284(48):33224-32. PubMed ID: 19805543
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]