BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

676 related articles for article (PubMed ID: 28002813)

  • 1. Sub-lethal oxidative stress induces lysosome biogenesis via a lysosomal membrane permeabilization-cathepsin-caspase 3-transcription factor EB-dependent pathway.
    Leow SM; Chua SX; Venkatachalam G; Shen L; Luo L; Clement MV
    Oncotarget; 2017 Mar; 8(10):16170-16189. PubMed ID: 28002813
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
    Rusmini P; Cortese K; Crippa V; Cristofani R; Cicardi ME; Ferrari V; Vezzoli G; Tedesco B; Meroni M; Messi E; Piccolella M; Galbiati M; Garrè M; Morelli E; Vaccari T; Poletti A
    Autophagy; 2019 Apr; 15(4):631-651. PubMed ID: 30335591
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The C-ETS2-TFEB Axis Promotes Neuron Survival under Oxidative Stress by Regulating Lysosome Activity.
    Ma S; Fang Z; Luo W; Yang Y; Wang C; Zhang Q; Wang H; Chen H; Chan CB; Liu Z
    Oxid Med Cell Longev; 2016; 2016():4693703. PubMed ID: 27195074
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Clomiphene citrate induces nuclear translocation of the TFEB transcription factor and triggers apoptosis by enhancing lysosomal membrane permeabilization.
    Li W; Lin J; Shi Z; Wen J; Li Y; Liu Z; Diao A
    Biochem Pharmacol; 2019 Apr; 162():191-201. PubMed ID: 30471247
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Curcumin targets the TFEB-lysosome pathway for induction of autophagy.
    Zhang J; Wang J; Xu J; Lu Y; Jiang J; Wang L; Shen HM; Xia D
    Oncotarget; 2016 Nov; 7(46):75659-75671. PubMed ID: 27689333
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis.
    Wang W; Xia Z; Farré JC; Subramani S
    Autophagy; 2018; 14(9):1574-1585. PubMed ID: 29940807
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Melatonin antagonizes cadmium-induced neurotoxicity by activating the transcription factor EB-dependent autophagy-lysosome machinery in mouse neuroblastoma cells.
    Li M; Pi H; Yang Z; Reiter RJ; Xu S; Chen X; Chen C; Zhang L; Yang M; Li Y; Guo P; Li G; Tu M; Tian L; Xie J; He M; Lu Y; Zhong M; Zhang Y; Yu Z; Zhou Z
    J Pineal Res; 2016 Oct; 61(3):353-69. PubMed ID: 27396692
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity.
    Zhitomirsky B; Yunaev A; Kreiserman R; Kaplan A; Stark M; Assaraf YG
    Cell Death Dis; 2018 Dec; 9(12):1191. PubMed ID: 30546014
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhancing lysosomal biogenesis and autophagic flux by activating the transcription factor EB protects against cadmium-induced neurotoxicity.
    Pi H; Li M; Tian L; Yang Z; Yu Z; Zhou Z
    Sci Rep; 2017 Feb; 7():43466. PubMed ID: 28240313
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of the transcription factor EB-PGC1α axis by beclin-1 controls mitochondrial quality and cardiomyocyte death under stress.
    Ma X; Liu H; Murphy JT; Foyil SR; Godar RJ; Abuirqeba H; Weinheimer CJ; Barger PM; Diwan A
    Mol Cell Biol; 2015 Mar; 35(6):956-76. PubMed ID: 25561470
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neuronal-targeted TFEB rescues dysfunction of the autophagy-lysosomal pathway and alleviates ischemic injury in permanent cerebral ischemia.
    Liu Y; Xue X; Zhang H; Che X; Luo J; Wang P; Xu J; Xing Z; Yuan L; Liu Y; Fu X; Su D; Sun S; Zhang H; Wu C; Yang J
    Autophagy; 2019 Mar; 15(3):493-509. PubMed ID: 30304977
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transcription Factor EB Expression in Early Breast Cancer Relates to Lysosomal/Autophagosomal Markers and Prognosis.
    Giatromanolaki A; Sivridis E; Kalamida D; Koukourakis MI
    Clin Breast Cancer; 2017 Jun; 17(3):e119-e125. PubMed ID: 28017540
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GDC-0941 enhances the lysosomal compartment via TFEB and primes glioblastoma cells to lysosomal membrane permeabilization and cell death.
    Enzenmüller S; Gonzalez P; Karpel-Massler G; Debatin KM; Fulda S
    Cancer Lett; 2013 Feb; 329(1):27-36. PubMed ID: 23000516
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Giant Cellular Vacuoles Induced by Rare Earth Oxide Nanoparticles are Abnormally Enlarged Endo/Lysosomes and Promote mTOR-Dependent TFEB Nucleus Translocation.
    Lin J; Shi SS; Zhang JQ; Zhang YJ; Zhang L; Liu Y; Jin PP; Wei PF; Shi RH; Zhou W; Wen LP
    Small; 2016 Nov; 12(41):5759-5768. PubMed ID: 27593892
    [TBL] [Abstract][Full Text] [Related]  

  • 15. VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.
    Arhzaouy K; Papadopoulos C; Schulze N; Pittman SK; Meyer H; Weihl CC
    Autophagy; 2019 Jun; 15(6):1082-1099. PubMed ID: 30654731
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy.
    Bartlett JJ; Trivedi PC; Yeung P; Kienesberger PC; Pulinilkunnil T
    Biochem J; 2016 Nov; 473(21):3769-3789. PubMed ID: 27487838
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The tumor suppressor p53 regulates autophagosomal and lysosomal biogenesis in lung cancer cells by targeting transcription factor EB.
    Zhang Z; Wang H; Ding Q; Xing Y; Xu D; Xu Z; Zhou T; Qian B; Ji C; Pan X; Zhong A; Ying Z; Zhou C; Shi M
    Biomed Pharmacother; 2017 May; 89():1055-1060. PubMed ID: 28292013
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Trehalose causes low-grade lysosomal stress to activate TFEB and the autophagy-lysosome biogenesis response.
    Jeong SJ; Stitham J; Evans TD; Zhang X; Rodriguez-Velez A; Yeh YS; Tao J; Takabatake K; Epelman S; Lodhi IJ; Schilling JD; DeBosch BJ; Diwan A; Razani B
    Autophagy; 2021 Nov; 17(11):3740-3752. PubMed ID: 33706671
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Repetitive stimulation of autophagy-lysosome machinery by intermittent fasting preconditions the myocardium to ischemia-reperfusion injury.
    Godar RJ; Ma X; Liu H; Murphy JT; Weinheimer CJ; Kovacs A; Crosby SD; Saftig P; Diwan A
    Autophagy; 2015; 11(9):1537-60. PubMed ID: 26103523
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased lysosomal biogenesis in activated microglia and exacerbated neuronal damage after traumatic brain injury in progranulin-deficient mice.
    Tanaka Y; Matsuwaki T; Yamanouchi K; Nishihara M
    Neuroscience; 2013 Oct; 250():8-19. PubMed ID: 23830905
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.