BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

348 related articles for article (PubMed ID: 28007623)

  • 1. Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance).
    Augert A; Zhang Q; Bates B; Cui M; Wang X; Wildey G; Dowlati A; MacPherson D
    J Thorac Oncol; 2017 Apr; 12(4):704-713. PubMed ID: 28007623
    [TBL] [Abstract][Full Text] [Related]  

  • 2. KMT2D Mutation Is Associated With Poor Prognosis in Non-Small-Cell Lung Cancer.
    Ardeshir-Larijani F; Bhateja P; Lipka MB; Sharma N; Fu P; Dowlati A
    Clin Lung Cancer; 2018 Jul; 19(4):e489-e501. PubMed ID: 29627316
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lung neuroendocrine tumours: deep sequencing of the four World Health Organization histotypes reveals chromatin-remodelling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D.
    Simbolo M; Mafficini A; Sikora KO; Fassan M; Barbi S; Corbo V; Mastracci L; Rusev B; Grillo F; Vicentini C; Ferrara R; Pilotto S; Davini F; Pelosi G; Lawlor RT; Chilosi M; Tortora G; Bria E; Fontanini G; Volante M; Scarpa A
    J Pathol; 2017 Mar; 241(4):488-500. PubMed ID: 27873319
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer.
    Peifer M; Fernández-Cuesta L; Sos ML; George J; Seidel D; Kasper LH; Plenker D; Leenders F; Sun R; Zander T; Menon R; Koker M; Dahmen I; Müller C; Di Cerbo V; Schildhaus HU; Altmüller J; Baessmann I; Becker C; de Wilde B; Vandesompele J; Böhm D; Ansén S; Gabler F; Wilkening I; Heynck S; Heuckmann JM; Lu X; Carter SL; Cibulskis K; Banerji S; Getz G; Park KS; Rauh D; Grütter C; Fischer M; Pasqualucci L; Wright G; Wainer Z; Russell P; Petersen I; Chen Y; Stoelben E; Ludwig C; Schnabel P; Hoffmann H; Muley T; Brockmann M; Engel-Riedel W; Muscarella LA; Fazio VM; Groen H; Timens W; Sietsma H; Thunnissen E; Smit E; Heideman DA; Snijders PJ; Cappuzzo F; Ligorio C; Damiani S; Field J; Solberg S; Brustugun OT; Lund-Iversen M; Sänger J; Clement JH; Soltermann A; Moch H; Weder W; Solomon B; Soria JC; Validire P; Besse B; Brambilla E; Brambilla C; Lantuejoul S; Lorimier P; Schneider PM; Hallek M; Pao W; Meyerson M; Sage J; Shendure J; Schneider R; Büttner R; Wolf J; Nürnberg P; Perner S; Heukamp LC; Brindle PK; Haas S; Thomas RK
    Nat Genet; 2012 Oct; 44(10):1104-10. PubMed ID: 22941188
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comprehensive genomic profiling of small cell lung cancer in Chinese patients and the implications for therapeutic potential.
    Hu J; Wang Y; Zhang Y; Yu Y; Chen H; Liu K; Yao M; Wang K; Gu W; Shou T
    Cancer Med; 2019 Aug; 8(9):4338-4347. PubMed ID: 31199602
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genetic Mutation Analysis in Small Cell Lung Cancer by a Novel NGS-Based Targeted Resequencing Gene Panel and Relation with Clinical Features.
    Jin W; Lei Z; Xu S; Fachen Z; Yixiang Z; Shilei Z; Tao G; Zhe S; Fengzhou L; Su WH; Chundong G
    Biomed Res Int; 2021; 2021():3609028. PubMed ID: 33880365
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Whole-exome sequencing defines the mutational landscape of pheochromocytoma and identifies KMT2D as a recurrently mutated gene.
    Juhlin CC; Stenman A; Haglund F; Clark VE; Brown TC; Baranoski J; Bilguvar K; Goh G; Welander J; Svahn F; Rubinstein JC; Caramuta S; Yasuno K; Günel M; Bäckdahl M; Gimm O; Söderkvist P; Prasad ML; Korah R; Lifton RP; Carling T
    Genes Chromosomes Cancer; 2015 Sep; 54(9):542-54. PubMed ID: 26032282
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Analysis of the feasibility and prognostic value of circulating tumor DNA in detecting gene mutations in small cell lung cancer].
    Jin Y; Chen YM; Hu X; Tang HR; Yu XM; Fan Y; Xu YJ; Xu HM; Li PS; Li Q; Chang LP; Guan YF; Chen M
    Zhonghua Yi Xue Za Zhi; 2020 Dec; 100(45):3614-3621. PubMed ID: 33333686
    [No Abstract]   [Full Text] [Related]  

  • 9. KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation.
    Guo C; Chen LH; Huang Y; Chang CC; Wang P; Pirozzi CJ; Qin X; Bao X; Greer PK; McLendon RE; Yan H; Keir ST; Bigner DD; He Y
    Oncotarget; 2013 Nov; 4(11):2144-53. PubMed ID: 24240169
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genomic alterations of plasma cell-free DNAs in small cell lung cancer and their clinical relevance.
    Du M; Thompson J; Fisher H; Zhang P; Huang CC; Wang L
    Lung Cancer; 2018 Jun; 120():113-121. PubMed ID: 29748005
    [TBL] [Abstract][Full Text] [Related]  

  • 11. KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer.
    Alam H; Tang M; Maitituoheti M; Dhar SS; Kumar M; Han CY; Ambati CR; Amin SB; Gu B; Chen TY; Lin YH; Chen J; Muller FL; Putluri N; Flores ER; DeMayo FJ; Baseler L; Rai K; Lee MG
    Cancer Cell; 2020 Apr; 37(4):599-617.e7. PubMed ID: 32243837
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutational landscape of homologous recombination-related genes in small-cell lung cancer.
    Wu S; Zhang Y; Zhang Y; Chen LH; Ouyang HF; Xu X; Du Y; Ti XY
    Cancer Med; 2023 Feb; 12(4):4486-4495. PubMed ID: 36053931
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Multi-region exome sequencing reveals the intratumoral heterogeneity of surgically resected small cell lung cancer.
    Zhou H; Hu Y; Luo R; Zhao Y; Pan H; Ji L; Zhou T; Zhang L; Long H; Fu J; Wen Z; Wang S; Wang X; Lin P; Yang H; Wang J; Song M; Yi X; Yang L; Xia X; Guan Y; Fang W; Yang Y; Hong S; Huang Y; Li P; Zhang Y; Zhou N
    Nat Commun; 2021 Sep; 12(1):5431. PubMed ID: 34521849
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prognostic impact of tumor mutation burden and the mutation in KIAA1211 in small cell lung cancer.
    Zhou M; Fan J; Li Z; Li P; Sun Y; Yang Y; Zhou X; Wang J; Wang Y; Qi H; Cai W; Dai X; Hirsch FR
    Respir Res; 2019 Nov; 20(1):248. PubMed ID: 31699089
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comprehensive genomic profiles of small cell lung cancer.
    George J; Lim JS; Jang SJ; Cun Y; Ozretić L; Kong G; Leenders F; Lu X; Fernández-Cuesta L; Bosco G; Müller C; Dahmen I; Jahchan NS; Park KS; Yang D; Karnezis AN; Vaka D; Torres A; Wang MS; Korbel JO; Menon R; Chun SM; Kim D; Wilkerson M; Hayes N; Engelmann D; Pützer B; Bos M; Michels S; Vlasic I; Seidel D; Pinther B; Schaub P; Becker C; Altmüller J; Yokota J; Kohno T; Iwakawa R; Tsuta K; Noguchi M; Muley T; Hoffmann H; Schnabel PA; Petersen I; Chen Y; Soltermann A; Tischler V; Choi CM; Kim YH; Massion PP; Zou Y; Jovanovic D; Kontic M; Wright GM; Russell PA; Solomon B; Koch I; Lindner M; Muscarella LA; la Torre A; Field JK; Jakopovic M; Knezevic J; Castaños-Vélez E; Roz L; Pastorino U; Brustugun OT; Lund-Iversen M; Thunnissen E; Köhler J; Schuler M; Botling J; Sandelin M; Sanchez-Cespedes M; Salvesen HB; Achter V; Lang U; Bogus M; Schneider PM; Zander T; Ansén S; Hallek M; Wolf J; Vingron M; Yatabe Y; Travis WD; Nürnberg P; Reinhardt C; Perner S; Heukamp L; Büttner R; Haas SA; Brambilla E; Peifer M; Sage J; Thomas RK
    Nature; 2015 Aug; 524(7563):47-53. PubMed ID: 26168399
    [TBL] [Abstract][Full Text] [Related]  

  • 16. KMT2D/MLL2 inactivation is associated with recurrence in adult-type granulosa cell tumors of the ovary.
    Hillman RT; Celestino J; Terranova C; Beird HC; Gumbs C; Little L; Nguyen T; Thornton R; Tippen S; Zhang J; Lu KH; Gershenson DM; Rai K; Broaddus RR; Futreal PA
    Nat Commun; 2018 Jun; 9(1):2496. PubMed ID: 29950560
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genomic based analyses reveal unique mutational profiling and identify prognostic biomarker for overall survival in Chinese small-cell lung cancer.
    Wang Y; Han X; Wang X; Sheng W; Chen Z; Shu W; Han J; Zhao S; Dai Y; Wang K; Shi W; Yang Z
    Jpn J Clin Oncol; 2019 Dec; 49(12):1143-1150. PubMed ID: 31612912
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Implementing amplicon-based next generation sequencing in the diagnosis of small cell lung carcinoma metastases.
    Meder L; König K; Fassunke J; Ozretić L; Wolf J; Merkelbach-Bruse S; Heukamp LC; Buettner R
    Exp Mol Pathol; 2015 Dec; 99(3):682-6. PubMed ID: 26546837
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Next-generation sequencing reveals frequent consistent genomic alterations in small cell undifferentiated lung cancer.
    Ross JS; Wang K; Elkadi OR; Tarasen A; Foulke L; Sheehan CE; Otto GA; Palmer G; Yelensky R; Lipson D; Chmielecki J; Ali SM; Elvin J; Morosini D; Miller VA; Stephens PJ
    J Clin Pathol; 2014 Sep; 67(9):772-6. PubMed ID: 24978188
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genomic features of Chinese small cell lung cancer.
    Liu J; Zhao Z; Wei S; Li B; Zhao Z
    BMC Med Genomics; 2022 May; 15(1):117. PubMed ID: 35596192
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.