BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

270 related articles for article (PubMed ID: 28009297)

  • 1. Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.
    Hinson JT; Chopra A; Lowe A; Sheng CC; Gupta RM; Kuppusamy R; O'Sullivan J; Rowe G; Wakimoto H; Gorham J; Burke MA; Zhang K; Musunuru K; Gerszten RE; Wu SM; Chen CS; Seidman JG; Seidman CE
    Cell Rep; 2016 Dec; 17(12):3292-3304. PubMed ID: 28009297
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutation in the γ2-subunit of AMP-activated protein kinase stimulates cardiomyocyte proliferation and hypertrophy independent of glycogen storage.
    Kim M; Hunter RW; Garcia-Menendez L; Gong G; Yang YY; Kolwicz SC; Xu J; Sakamoto K; Wang W; Tian R
    Circ Res; 2014 Mar; 114(6):966-75. PubMed ID: 24503893
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transgenic knockdown of cardiac sodium/glucose cotransporter 1 (SGLT1) attenuates PRKAG2 cardiomyopathy, whereas transgenic overexpression of cardiac SGLT1 causes pathologic hypertrophy and dysfunction in mice.
    Ramratnam M; Sharma RK; D'Auria S; Lee SJ; Wang D; Huang XY; Ahmad F
    J Am Heart Assoc; 2014 Aug; 3(4):. PubMed ID: 25092788
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy.
    Arad M; Moskowitz IP; Patel VV; Ahmad F; Perez-Atayde AR; Sawyer DB; Walter M; Li GH; Burgon PG; Maguire CT; Stapleton D; Schmitt JP; Guo XX; Pizard A; Kupershmidt S; Roden DM; Berul CI; Seidman CE; Seidman JG
    Circulation; 2003 Jun; 107(22):2850-6. PubMed ID: 12782567
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased alpha2 subunit-associated AMPK activity and PRKAG2 cardiomyopathy.
    Ahmad F; Arad M; Musi N; He H; Wolf C; Branco D; Perez-Atayde AR; Stapleton D; Bali D; Xing Y; Tian R; Goodyear LJ; Berul CI; Ingwall JS; Seidman CE; Seidman JG
    Circulation; 2005 Nov; 112(20):3140-8. PubMed ID: 16275868
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel, de novo mutation in the
    Xu Y; Gray A; Hardie DG; Uzun A; Shaw S; Padbury J; Phornphutkul C; Tseng YT
    Am J Physiol Heart Circ Physiol; 2017 Aug; 313(2):H283-H292. PubMed ID: 28550180
    [No Abstract]   [Full Text] [Related]  

  • 7. Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy.
    Arad M; Benson DW; Perez-Atayde AR; McKenna WJ; Sparks EA; Kanter RJ; McGarry K; Seidman JG; Seidman CE
    J Clin Invest; 2002 Feb; 109(3):357-62. PubMed ID: 11827995
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification and functional analysis of a novel PRKAG2 mutation responsible for Chinese PRKAG2 cardiac syndrome reveal an important role of non-CBS domains in regulating the AMPK pathway.
    Zhang BL; Xu RL; Zhang J; Zhao XX; Wu H; Ma LP; Hu JQ; Zhang JL; Ye Z; Zheng X; Qin YW
    J Cardiol; 2013 Oct; 62(4):241-8. PubMed ID: 23778007
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Establishment of a PRKAG2 cardiac syndrome disease model and mechanism study using human induced pluripotent stem cells.
    Zhan Y; Sun X; Li B; Cai H; Xu C; Liang Q; Lu C; Qian R; Chen S; Yin L; Sheng W; Huang G; Sun A; Ge J; Sun N
    J Mol Cell Cardiol; 2018 Apr; 117():49-61. PubMed ID: 29452156
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fatal congenital heart glycogenosis caused by a recurrent activating R531Q mutation in the gamma 2-subunit of AMP-activated protein kinase (PRKAG2), not by phosphorylase kinase deficiency.
    Burwinkel B; Scott JW; Bührer C; van Landeghem FK; Cox GF; Wilson CJ; Grahame Hardie D; Kilimann MW
    Am J Hum Genet; 2005 Jun; 76(6):1034-49. PubMed ID: 15877279
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of a novel de novo mutation associated with PRKAG2 cardiac syndrome and early onset of heart failure.
    Liu Y; Bai R; Wang L; Zhang C; Zhao R; Wan D; Chen X; Caceres G; Barr D; Barajas-Martinez H; Antzelevitch C; Hu D
    PLoS One; 2013; 8(5):e64603. PubMed ID: 23741347
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of the pathogenic effects of missense variants causing PRKAG2 cardiomyopathy.
    Komurcu-Bayrak E; Kalkan MA; Coban N; Ozsait-Selcuk B; Bayrak F
    Arch Biochem Biophys; 2022 Sep; 727():109340. PubMed ID: 35787834
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CRISPR correction of the PRKAG2 gene mutation in the patient's induced pluripotent stem cell-derived cardiomyocytes eliminates electrophysiological and structural abnormalities.
    Ben Jehuda R; Eisen B; Shemer Y; Mekies LN; Szantai A; Reiter I; Cui H; Guan K; Haron-Khun S; Freimark D; Sperling SR; Gherghiceanu M; Arad M; Binah O
    Heart Rhythm; 2018 Feb; 15(2):267-276. PubMed ID: 28917552
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glycogen storage diseases presenting as hypertrophic cardiomyopathy.
    Arad M; Maron BJ; Gorham JM; Johnson WH; Saul JP; Perez-Atayde AR; Spirito P; Wright GB; Kanter RJ; Seidman CE; Seidman JG
    N Engl J Med; 2005 Jan; 352(4):362-72. PubMed ID: 15673802
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Distinct early signaling events resulting from the expression of the PRKAG2 R302Q mutant of AMPK contribute to increased myocardial glycogen.
    Folmes KD; Chan AY; Koonen DP; Pulinilkunnil TC; Baczkó I; Hunter BE; Thorn S; Allard MF; Roberts R; Gollob MH; Light PE; Dyck JR
    Circ Cardiovasc Genet; 2009 Oct; 2(5):457-66. PubMed ID: 20031621
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cardiovascular magnetic resonance findings in patients with PRKAG2 gene mutations.
    Pöyhönen P; Hiippala A; Ollila L; Kaasalainen T; Hänninen H; Heliö T; Tallila J; Vasilescu C; Kivistö S; Ojala T; Holmström M
    J Cardiovasc Magn Reson; 2015 Oct; 17():89. PubMed ID: 26496977
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutation analysis of AMP-activated protein kinase subunits in inherited cardiomyopathies: implications for kinase function and disease pathogenesis.
    Oliveira SM; Ehtisham J; Redwood CS; Ostman-Smith I; Blair EM; Watkins H
    J Mol Cell Cardiol; 2003 Oct; 35(10):1251-5. PubMed ID: 14519435
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human γ2-AMPK Mutations.
    Yavari A; Sarma D; Sternick EB
    Methods Mol Biol; 2018; 1732():581-619. PubMed ID: 29480501
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [AMP-activated protein kinase: how a mistake in energy gauge causes glycogen storage].
    Ofir M; Hochhauser E; Vidne BA; Freimark D; Arad M
    Harefuah; 2007 Oct; 146(10):770-5, 813-4. PubMed ID: 17990392
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Clinical Features and Natural History of PRKAG2 Variant Cardiac Glycogenosis.
    Lopez-Sainz A; Dominguez F; Lopes LR; Ochoa JP; Barriales-Villa R; Climent V; Linschoten M; Tiron C; Chiriatti C; Marques N; Rasmussen TB; Espinosa MÁ; Beinart R; Quarta G; Cesar S; Field E; Garcia-Pinilla JM; Bilinska Z; Muir AR; Roberts AM; Santas E; Zorio E; Peña-Peña ML; Navarro M; Fernandez A; Palomino-Doza J; Azevedo O; Lorenzini M; García-Álvarez MI; Bento D; Jensen MK; Méndez I; Pezzoli L; Sarquella-Brugada G; Campuzano O; Gonzalez-Lopez E; Mogensen J; Kaski JP; Arad M; Brugada R; Asselbergs FW; Monserrat L; Olivotto I; Elliott PM; Garcia-Pavia P;
    J Am Coll Cardiol; 2020 Jul; 76(2):186-197. PubMed ID: 32646569
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.