BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

810 related articles for article (PubMed ID: 28010732)

  • 1. The effect of a germline mutation in the APC gene on β-catenin in human embryonic stem cells.
    Yedid N; Kalma Y; Malcov M; Amit A; Kariv R; Caspi M; Rosin-Arbesfeld R; Ben-Yosef D
    BMC Cancer; 2016 Dec; 16(1):952. PubMed ID: 28010732
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Heterozygous APC germline mutations impart predisposition to colorectal cancer.
    Preisler L; Habib A; Shapira G; Kuznitsov-Yanovsky L; Mayshar Y; Carmel-Gross I; Malcov M; Azem F; Shomron N; Kariv R; Hershkovitz D; Ben-Yosef D
    Sci Rep; 2021 Mar; 11(1):5113. PubMed ID: 33664379
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Adenomatous Polyposis Coli as a Major Regulator of Human Embryonic Stem Cells Self-Renewal.
    Preisler L; Ben-Yosef D; Mayshar Y
    Stem Cells; 2019 Dec; 37(12):1505-1515. PubMed ID: 31461190
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ovarian steroid cell tumor with biallelic adenomatous polyposis coli inactivation in a patient with familial adenomatous polyposis.
    Hu PJ; Knoepp SM; Wu R; Cho KR
    Genes Chromosomes Cancer; 2012 Mar; 51(3):283-9. PubMed ID: 22120905
    [TBL] [Abstract][Full Text] [Related]  

  • 5. miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4.
    Prossomariti A; Piazzi G; D'Angelo L; Miccoli S; Turchetti D; Alquati C; Montagna C; Bazzoli F; Ricciardiello L
    Mol Cancer Res; 2018 Dec; 16(12):1965-1976. PubMed ID: 30072583
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade.
    Albuquerque C; Breukel C; van der Luijt R; Fidalgo P; Lage P; Slors FJ; Leitão CN; Fodde R; Smits R
    Hum Mol Genet; 2002 Jun; 11(13):1549-60. PubMed ID: 12045208
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inactivation of the APC gene is constant in adrenocortical tumors from patients with familial adenomatous polyposis but not frequent in sporadic adrenocortical cancers.
    Gaujoux S; Pinson S; Gimenez-Roqueplo AP; Amar L; Ragazzon B; Launay P; Meatchi T; Libé R; Bertagna X; Audebourg A; Zucman-Rossi J; Tissier F; Bertherat J
    Clin Cancer Res; 2010 Nov; 16(21):5133-41. PubMed ID: 20978149
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutation cluster region, association between germline and somatic mutations and genotype-phenotype correlation in upper gastrointestinal familial adenomatous polyposis.
    Groves C; Lamlum H; Crabtree M; Williamson J; Taylor C; Bass S; Cuthbert-Heavens D; Hodgson S; Phillips R; Tomlinson I
    Am J Pathol; 2002 Jun; 160(6):2055-61. PubMed ID: 12057910
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oncogenic KRAS is not necessary for Wnt signalling activation in APC-associated FAP adenomas.
    Obrador-Hevia A; Chin SF; González S; Rees J; Vilardell F; Greenson JK; Cordero D; Moreno V; Caldas C; Capellá G
    J Pathol; 2010 May; 221(1):57-67. PubMed ID: 20196079
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeted next-generation sequencing approach for molecular genetic diagnosis of hereditary colorectal cancer: Identification of a novel single nucleotide germline insertion in adenomatous polyposis coli gene causes familial adenomatous polyposis.
    Wang D; Liang S; Zhang X; Dey SK; Li Y; Xu C; Yu Y; Li M; Zhao G; Zhang Z
    Mol Genet Genomic Med; 2019 Jan; 7(1):e00505. PubMed ID: 30523670
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A neoepitope derived from a novel human germline APC gene mutation in familial adenomatous polyposis shows selective immunogenicity.
    Majumder S; Shah R; Elias J; Mistry Y; Coral K; Shah P; Maurya AK; Mittal B; D'Silva JK; Murugan S; Mahadevan L; Sathian R; Ramprasad VL; Chakraborty P; Gupta R; Chaudhuri A; Khanna-Gupta A
    PLoS One; 2018; 13(9):e0203845. PubMed ID: 30256815
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Germline mutations are frequent in the APC gene but absent in the beta-catenin gene in familial adenomatous polyposis patients.
    Cao X; Eu KW; Seow-Choen F; Cheah PY
    Genes Chromosomes Cancer; 1999 Aug; 25(4):396-8. PubMed ID: 10398435
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Refining the relation between 'first hits' and 'second hits' at the APC locus: the 'loose fit' model and evidence for differences in somatic mutation spectra among patients.
    Crabtree M; Sieber OM; Lipton L; Hodgson SV; Lamlum H; Thomas HJ; Neale K; Phillips RK; Heinimann K; Tomlinson IP
    Oncogene; 2003 Jul; 22(27):4257-65. PubMed ID: 12833148
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inactivation of germline mutant APC alleles by attenuated somatic mutations: a molecular genetic mechanism for attenuated familial adenomatous polyposis.
    Su LK; Barnes CJ; Yao W; Qi Y; Lynch PM; Steinbach G
    Am J Hum Genet; 2000 Sep; 67(3):582-90. PubMed ID: 10924409
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Familial adenomatous polyposis syndrome (FAP): pathogenesis and molecular mechanisms].
    Friedrich A; Kullmann F
    Med Klin (Munich); 2003 Dec; 98(12):776-82. PubMed ID: 14685680
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analysis of K-ras, APC, and beta-catenin in aberrant crypt foci in sporadic adenoma, cancer, and familial adenomatous polyposis.
    Takayama T; Ohi M; Hayashi T; Miyanishi K; Nobuoka A; Nakajima T; Satoh T; Takimoto R; Kato J; Sakamaki S; Niitsu Y
    Gastroenterology; 2001 Sep; 121(3):599-611. PubMed ID: 11522744
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of somatic APC mutations in rare extracolonic tumors of patients with familial adenomatous polyposis coli.
    Bläker H; Sutter C; Kadmon M; Otto HF; Von Knebel-Doeberitz M; Gebert J; Helmke BM
    Genes Chromosomes Cancer; 2004 Oct; 41(2):93-8. PubMed ID: 15287021
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis.
    Gaspar C; Franken P; Molenaar L; Breukel C; van der Valk M; Smits R; Fodde R
    PLoS Genet; 2009 Jul; 5(7):e1000547. PubMed ID: 19578404
    [TBL] [Abstract][Full Text] [Related]  

  • 19. APC mutations in FAP-associated desmoid tumours are non-random but not 'just right'.
    Latchford A; Volikos E; Johnson V; Rogers P; Suraweera N; Tomlinson I; Phillips R; Silver A
    Hum Mol Genet; 2007 Jan; 16(1):78-82. PubMed ID: 17135276
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A beta-catenin mutation in a sporadic colorectal tumor of the RER phenotype and absence of beta-catenin germline mutations in FAP patients.
    Müller O; Nimmrich I; Finke U; Friedl W; Hoffmann I
    Genes Chromosomes Cancer; 1998 May; 22(1):37-41. PubMed ID: 9591632
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 41.