193 related articles for article (PubMed ID: 28011125)
1. Prediction of Ketoconazole absorption using an updated in vitro transfer model coupled to physiologically based pharmacokinetic modelling.
Ruff A; Fiolka T; Kostewicz ES
Eur J Pharm Sci; 2017 Mar; 100():42-55. PubMed ID: 28011125
[TBL] [Abstract][Full Text] [Related]
2. Model-Based Analysis of Biopharmaceutic Experiments To Improve Mechanistic Oral Absorption Modeling: An Integrated in Vitro in Vivo Extrapolation Perspective Using Ketoconazole as a Model Drug.
Pathak SM; Ruff A; Kostewicz ES; Patel N; Turner DB; Jamei M
Mol Pharm; 2017 Dec; 14(12):4305-4320. PubMed ID: 28771009
[TBL] [Abstract][Full Text] [Related]
3. The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS).
Tsume Y; Matsui K; Searls AL; Takeuchi S; Amidon GE; Sun D; Amidon GL
Eur J Pharm Sci; 2017 May; 102():126-139. PubMed ID: 28263914
[TBL] [Abstract][Full Text] [Related]
4. Prediction of oral absorption of cinnarizine--a highly supersaturating poorly soluble weak base with borderline permeability.
Berlin M; Przyklenk KH; Richtberg A; Baumann W; Dressman JB
Eur J Pharm Biopharm; 2014 Nov; 88(3):795-806. PubMed ID: 25195981
[TBL] [Abstract][Full Text] [Related]
5. Assessment of Bioequivalence of Weak Base Formulations Under Various Dosing Conditions Using Physiologically Based Pharmacokinetic Simulations in Virtual Populations. Case Examples: Ketoconazole and Posaconazole.
Cristofoletti R; Patel N; Dressman JB
J Pharm Sci; 2017 Feb; 106(2):560-569. PubMed ID: 27865610
[TBL] [Abstract][Full Text] [Related]
6. Precipitation in the small intestine may play a more important role in the in vivo performance of poorly soluble weak bases in the fasted state: case example nelfinavir.
Shono Y; Jantratid E; Dressman JB
Eur J Pharm Biopharm; 2011 Oct; 79(2):349-56. PubMed ID: 21527341
[TBL] [Abstract][Full Text] [Related]
7. In vitro-in vivo correlation of the effect of supersaturation on the intestinal absorption of BCS Class 2 drugs.
Higashino H; Hasegawa T; Yamamoto M; Matsui R; Masaoka Y; Kataoka M; Sakuma S; Yamashita S
Mol Pharm; 2014 Mar; 11(3):746-54. PubMed ID: 24460473
[TBL] [Abstract][Full Text] [Related]
8. Prediction of the precipitation profiles of weak base drugs in the small intestine using a simplified transfer ("dumping") model coupled with in silico modeling and simulation approach.
Kambayashi A; Yasuji T; Dressman JB
Eur J Pharm Biopharm; 2016 Jun; 103():95-103. PubMed ID: 27012902
[TBL] [Abstract][Full Text] [Related]
9. Integration of Precipitation Kinetics From an In Vitro, Multicompartment Transfer System and Mechanistic Oral Absorption Modeling for Pharmacokinetic Prediction of Weakly Basic Drugs.
Patel S; Zhu W; Xia B; Sharma N; Hermans A; Ehrick JD; Kesisoglou F; Pennington J
J Pharm Sci; 2019 Jan; 108(1):574-583. PubMed ID: 30395833
[TBL] [Abstract][Full Text] [Related]
10. Predicting the oral absorption of a poorly soluble, poorly permeable weak base using biorelevant dissolution and transfer model tests coupled with a physiologically based pharmacokinetic model.
Wagner C; Jantratid E; Kesisoglou F; Vertzoni M; Reppas C; B Dressman J
Eur J Pharm Biopharm; 2012 Sep; 82(1):127-38. PubMed ID: 22652546
[TBL] [Abstract][Full Text] [Related]
11. In Vitro Assessment of Supersaturation/Precipitation and Biological Membrane Permeation of Poorly Water-Soluble Drugs: A Case Study With Albendazole and Ketoconazole.
Kataoka M; Takeyama S; Minami K; Higashino H; Kakimi K; Fujii Y; Takahashi M; Yamashita S
J Pharm Sci; 2019 Aug; 108(8):2580-2587. PubMed ID: 30885658
[TBL] [Abstract][Full Text] [Related]
12. Effect of surfactants, gastric emptying, and dosage form on supersaturation of dipyridamole in an in vitro model simulating the stomach and duodenum.
Mitra A; Fadda HM
Mol Pharm; 2014 Aug; 11(8):2835-44. PubMed ID: 25025699
[TBL] [Abstract][Full Text] [Related]
13. In Silico Modeling Approach for the Evaluation of Gastrointestinal Dissolution, Supersaturation, and Precipitation of Posaconazole.
Hens B; Pathak SM; Mitra A; Patel N; Liu B; Patel S; Jamei M; Brouwers J; Augustijns P; Turner DB
Mol Pharm; 2017 Dec; 14(12):4321-4333. PubMed ID: 28817288
[TBL] [Abstract][Full Text] [Related]
14. PBPK models for the prediction of in vivo performance of oral dosage forms.
Kostewicz ES; Aarons L; Bergstrand M; Bolger MB; Galetin A; Hatley O; Jamei M; Lloyd R; Pepin X; Rostami-Hodjegan A; Sjögren E; Tannergren C; Turner DB; Wagner C; Weitschies W; Dressman J
Eur J Pharm Sci; 2014 Jun; 57():300-21. PubMed ID: 24060672
[TBL] [Abstract][Full Text] [Related]
15. Improved Prediction of in Vivo Supersaturation and Precipitation of Poorly Soluble Weakly Basic Drugs Using a Biorelevant Bicarbonate Buffer in a Gastrointestinal Transfer Model.
Jede C; Wagner C; Kubas H; Weigandt M; Weber C; Lecomte M; Badolo L; Koziolek M; Weitschies W
Mol Pharm; 2019 Sep; 16(9):3938-3947. PubMed ID: 31335153
[TBL] [Abstract][Full Text] [Related]
16. Impact of amorphization and GI physiology on supersaturation and precipitation of poorly soluble weakly basic drugs using a small-scale in vitro transfer model.
Auch C; Jede C; Harms M; Wagner C; Mäder K
Int J Pharm; 2020 Jan; 574():118917. PubMed ID: 31811926
[TBL] [Abstract][Full Text] [Related]
17. Control of Dissolution and Supersaturation/Precipitation of Poorly Water-Soluble Drugs from Cocrystals Based on Solubility Products: A Case Study with a Ketoconazole Cocrystal.
Kataoka M; Yonehara A; Minami K; Takagi T; Yamashita S
Mol Pharm; 2023 Aug; 20(8):4100-4107. PubMed ID: 37354097
[TBL] [Abstract][Full Text] [Related]
18. Predicting the precipitation of poorly soluble weak bases upon entry in the small intestine.
Kostewicz ES; Wunderlich M; Brauns U; Becker R; Bock T; Dressman JB
J Pharm Pharmacol; 2004 Jan; 56(1):43-51. PubMed ID: 14980000
[TBL] [Abstract][Full Text] [Related]
19. In vitro dissolution methodology, mini-Gastrointestinal Simulator (mGIS), predicts better in vivo dissolution of a weak base drug, dasatinib.
Tsume Y; Takeuchi S; Matsui K; Amidon GE; Amidon GL
Eur J Pharm Sci; 2015 Aug; 76():203-12. PubMed ID: 25978875
[TBL] [Abstract][Full Text] [Related]
20. Precipitation in and supersaturation of contents of the upper small intestine after administration of two weak bases to fasted adults.
Psachoulias D; Vertzoni M; Goumas K; Kalioras V; Beato S; Butler J; Reppas C
Pharm Res; 2011 Dec; 28(12):3145-58. PubMed ID: 21674262
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
