BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 28013366)

  • 1. Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design.
    Roy R; Cao Y; Kaltner H; Kottari N; Shiao TC; Belkhadem K; André S; Manning JC; Murphy PV; Gabius HJ
    Histochem Cell Biol; 2017 Feb; 147(2):285-301. PubMed ID: 28013366
    [TBL] [Abstract][Full Text] [Related]  

  • 2. First demonstration of differential inhibition of lectin binding by synthetic tri- and tetravalent glycoclusters from cross-coupling of rigidified 2-propynyl lactoside.
    André S; Liu B; Gabius HJ; Roy R
    Org Biomol Chem; 2003 Nov; 1(22):3909-16. PubMed ID: 14664382
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Defining the potential of aglycone modifications for affinity/selectivity enhancement against medically relevant lectins: synthesis, activity screening, and HSQC-based NMR analysis.
    Rauthu SR; Shiao TC; André S; Miller MC; Madej É; Mayo KH; Gabius HJ; Roy R
    Chembiochem; 2015 Jan; 16(1):126-39. PubMed ID: 25407851
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Galectin-loaded cells as a platform for the profiling of lectin specificity by fluorescent neoglycoconjugates: a case study on galectins-1 and -3 and the impact of assay setting.
    Rapoport EM; André S; Kurmyshkina OV; Pochechueva TV; Severov VV; Pazynina GV; Gabius HJ; Bovin NV
    Glycobiology; 2008 Apr; 18(4):315-24. PubMed ID: 18256179
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Calix[n]arene-based glycoclusters: bioactivity of thiourea-linked galactose/lactose moieties as inhibitors of binding of medically relevant lectins to a glycoprotein and cell-surface glycoconjugates and selectivity among human adhesion/growth-regulatory galectins.
    André S; Sansone F; Kaltner H; Casnati A; Kopitz J; Gabius HJ; Ungaro R
    Chembiochem; 2008 Jul; 9(10):1649-61. PubMed ID: 18509838
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bi- to tetravalent glycoclusters: synthesis, structure-activity profiles as lectin inhibitors and impact of combining both valency and headgroup tailoring on selectivity.
    Wang GN; André S; Gabius HJ; Murphy PV
    Org Biomol Chem; 2012 Sep; 10(34):6893-907. PubMed ID: 22842468
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Merging carbohydrate chemistry with lectin histochemistry to study inhibition of lectin binding by glycoclusters in the natural tissue context.
    André S; Kaltner H; Kayser K; Murphy PV; Gabius HJ
    Histochem Cell Biol; 2016 Feb; 145(2):185-99. PubMed ID: 26553286
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthetic Mucin-Like Glycopeptides as Versatile Tools to Measure Effects of Glycan Structure/Density/Position on the Interaction with Adhesion/Growth-Regulatory Galectins in Arrays.
    Artigas G; Hinou H; Garcia-Martin F; Gabius HJ; Nishimura SI
    Chem Asian J; 2017 Jan; 12(1):159-167. PubMed ID: 27873468
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bivalent O-glycoside mimetics with S/disulfide/Se substitutions and aromatic core: Synthesis, molecular modeling and inhibitory activity on biomedically relevant lectins in assays of increasing physiological relevance.
    Kaltner H; Szabó T; Fehér K; André S; Balla S; Manning JC; Szilágyi L; Gabius HJ
    Bioorg Med Chem; 2017 Jun; 25(12):3158-3170. PubMed ID: 28483453
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Playing Modular Puzzle with Adhesion/Growth-Regulatory Galectins: Design and Testing of a Hybrid to Unravel Structure-Activity Relationships.
    Ludwig AK; Vértesy S; Michalak M; Manning JC; Andre S; Kubler D; Kopitz J; Kaltner H; Gabius HJ
    Protein Pept Lett; 2016; 23(11):1003-1012. PubMed ID: 27697034
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of bivalent lactosides based on terephthalamide, N,N'-diglucosylterephthalamide, and glycophane scaffolds and assessment of their inhibitory capacity on medically relevant lectins.
    Leyden R; Velasco-Torrijos T; André S; Gouin S; Gabius HJ; Murphy PV
    J Org Chem; 2009 Dec; 74(23):9010-26. PubMed ID: 19899775
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting osteoarthritis-associated galectins and an induced effector class by a ditopic bifunctional reagent: Impact of its glycan part on binding measured in the tissue context.
    Manning JC; Baldoneschi V; Romero-Hernández LL; Pichler KM; GarcÍa Caballero G; André S; Kutzner TJ; Ludwig AK; Zullo V; Richichi B; Windhager R; Kaltner H; Toegel S; Gabius HJ; Murphy PV; Nativi C
    Bioorg Med Chem; 2022 Dec; 75():117068. PubMed ID: 36327696
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lectin-mediated drug targeting: selection of valency, sugar type (Gal/Lac), and spacer length for cluster glycosides as parameters to distinguish ligand binding to C-type asialoglycoprotein receptors and galectins.
    André S; Frisch B; Kaltner H; Desouza DL; Schuber F; Gabius HJ
    Pharm Res; 2000 Aug; 17(8):985-90. PubMed ID: 11028946
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glycobiology of developing chicken kidney: Profiling the galectin family and selected β-galactosides.
    Manning JC; García Caballero G; Ludwig AK; Kaltner H; Sinowatz F; Gabius HJ
    Anat Rec (Hoboken); 2021 Aug; 304(8):1597-1628. PubMed ID: 33119962
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multivalent Carbohydrate-Lectin Interactions: How Synthetic Chemistry Enables Insights into Nanometric Recognition.
    Roy R; Murphy PV; Gabius HJ
    Molecules; 2016 May; 21(5):. PubMed ID: 27187342
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analysis of selected blood and immune cell responses to carbohydrate-dependent surface binding of proto- and chimera-type galectins.
    Timoshenko AV; Gorudko IV; Maslakova OV; André S; Kuwabara I; Liu FT; Kaltner H; Gabius HJ
    Mol Cell Biochem; 2003 Aug; 250(1-2):139-49. PubMed ID: 12962152
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of bivalent lactosides and their activity as sensors for differences between lectins in inter- and intrafamily comparisons.
    André S; Jarikote DV; Yan D; Vincenz L; Wang GN; Kaltner H; Murphy PV; Gabius HJ
    Bioorg Med Chem Lett; 2012 Jan; 22(1):313-8. PubMed ID: 22142540
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Quantitation and histochemical localization of galectin-1 and galectin-1-reactive glycoconjugates in fetal development of bovine organs.
    Kaltner H; Lips KS; Reuter G; Lippert S; Sinowatz F; Gabius HJ
    Histol Histopathol; 1997 Oct; 12(4):945-60. PubMed ID: 9302557
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Persubstituted cyclodextrin-based glycoclusters as inhibitors of protein-carbohydrate recognition using purified plant and mammalian lectins and wild-type and lectin-gene-transfected tumor cells as targets.
    André S; Kaltner H; Furuike T; Nishimura S; Gabius HJ
    Bioconjug Chem; 2004; 15(1):87-98. PubMed ID: 14733587
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bi- to tetravalent glycoclusters presenting GlcNAc/GalNAc as inhibitors: from plant agglutinins to human macrophage galactose-type lectin (CD301) and galectins.
    André S; O'Sullivan S; Koller C; Murphy PV; Gabius HJ
    Org Biomol Chem; 2015 Apr; 13(14):4190-203. PubMed ID: 25721929
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.