255 related articles for article (PubMed ID: 28026162)
1. hBfl-1/hNOXA Interaction Studies Provide New Insights on the Role of Bfl-1 in Cancer Cell Resistance and for the Design of Novel Anticancer Agents.
Barile E; Marconi GD; De SK; Baggio C; Gambini L; Salem AF; Kashyap MK; Castro JE; Kipps TJ; Pellecchia M
ACS Chem Biol; 2017 Feb; 12(2):444-455. PubMed ID: 28026162
[TBL] [Abstract][Full Text] [Related]
2. Relationship between helix stability and binding affinities: molecular dynamics simulations of Bfl-1/A1-binding pro-apoptotic BH3 peptide helices in explicit solvent.
Modi V; Lama D; Sankararamakrishnan R
J Biomol Struct Dyn; 2013; 31(1):65-77. PubMed ID: 22803956
[TBL] [Abstract][Full Text] [Related]
3. Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor.
Harvey EP; Seo HS; Guerra RM; Bird GH; Dhe-Paganon S; Walensky LD
Structure; 2018 Jan; 26(1):153-160.e4. PubMed ID: 29276033
[TBL] [Abstract][Full Text] [Related]
4. Selective Covalent Targeting of Anti-Apoptotic BFL-1 by Cysteine-Reactive Stapled Peptide Inhibitors.
Huhn AJ; Guerra RM; Harvey EP; Bird GH; Walensky LD
Cell Chem Biol; 2016 Sep; 23(9):1123-1134. PubMed ID: 27617850
[TBL] [Abstract][Full Text] [Related]
5. Identification of Small Inhibitory Molecules Targeting the Bfl-1 Anti-Apoptotic Protein That Alleviates Resistance to ABT-737.
Mathieu AL; Sperandio O; Pottiez V; Balzarin S; Herlédan A; Elkaïm JO; Fogeron ML; Piveteau C; Dassonneville S; Deprez B; Villoutreix BO; Bonnefoy N; Leroux F
J Biomol Screen; 2014 Aug; 19(7):1035-46. PubMed ID: 24809353
[TBL] [Abstract][Full Text] [Related]
6. Antiapoptotic potency of Bcl-2 proteins primarily relies on their stability, not binding selectivity.
Rooswinkel RW; van de Kooij B; de Vries E; Paauwe M; Braster R; Verheij M; Borst J
Blood; 2014 May; 123(18):2806-15. PubMed ID: 24622325
[TBL] [Abstract][Full Text] [Related]
7. Binding affinity of pro-apoptotic BH3 peptides for the anti-apoptotic Mcl-1 and A1 proteins: Molecular dynamics simulations of Mcl-1 and A1 in complex with six different BH3 peptides.
Modi V; Sankararamakrishnan R
J Mol Graph Model; 2017 May; 73():115-128. PubMed ID: 28279820
[TBL] [Abstract][Full Text] [Related]
8. Peptide ligands for pro-survival protein Bfl-1 from computationally guided library screening.
Dutta S; Chen TS; Keating AE
ACS Chem Biol; 2013 Apr; 8(4):778-88. PubMed ID: 23363053
[TBL] [Abstract][Full Text] [Related]
9. Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering.
Harvey EP; Hauseman ZJ; Cohen DT; Rettenmaier TJ; Lee S; Huhn AJ; Wales TE; Seo HS; Luccarelli J; Newman CE; Guerra RM; Bird GH; Dhe-Paganon S; Engen JR; Wells JA; Walensky LD
Cell Chem Biol; 2020 Jun; 27(6):647-656.e6. PubMed ID: 32413285
[TBL] [Abstract][Full Text] [Related]
10. Binding modes of Bcl-2 homology 3 (BH3) peptides with anti-apoptotic protein A1 and redesign of peptide inhibitors: a computational study.
Chen Y; Wang J; Zhang J; Wang W
J Biomol Struct Dyn; 2018 Nov; 36(15):3967-3977. PubMed ID: 29137527
[TBL] [Abstract][Full Text] [Related]
11. Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells.
Feng X; Yan Z; Zhou F; Lou J; Lyu X; Ren X; Zeng Z; Liu C; Zhang S; Zhu D; Huang H; Yang J; Zhao Y
Eur J Med Chem; 2022 Jun; 236():114327. PubMed ID: 35385805
[TBL] [Abstract][Full Text] [Related]
12. Robust lanthanide-based assays for the detection of anti-apoptotic Bcl-2-family protein antagonists.
Rega MF; Reed JC; Pellecchia M
Bioorg Chem; 2007 Apr; 35(2):113-20. PubMed ID: 16996562
[TBL] [Abstract][Full Text] [Related]
13. Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist.
Simmons MJ; Fan G; Zong WX; Degenhardt K; White E; Gélinas C
Oncogene; 2008 Feb; 27(10):1421-8. PubMed ID: 17724464
[TBL] [Abstract][Full Text] [Related]
14. Precision Targeting of BFL-1/A1 and an ATM Co-dependency in Human Cancer.
Guerra RM; Bird GH; Harvey EP; Dharia NV; Korshavn KJ; Prew MS; Stegmaier K; Walensky LD
Cell Rep; 2018 Sep; 24(13):3393-3403.e5. PubMed ID: 30257201
[TBL] [Abstract][Full Text] [Related]
15. Determinants of BH3 binding specificity for Mcl-1 versus Bcl-xL.
Dutta S; Gullá S; Chen TS; Fire E; Grant RA; Keating AE
J Mol Biol; 2010 May; 398(5):747-62. PubMed ID: 20363230
[TBL] [Abstract][Full Text] [Related]
16. Functional dissection of Bfl-1, a Bcl-2 homolog: anti-apoptosis, oncogene-cooperation and cell proliferation activities.
D'Sa-Eipper C; Chinnadurai G
Oncogene; 1998 Jun; 16(24):3105-14. PubMed ID: 9671389
[TBL] [Abstract][Full Text] [Related]
17. Potent and specific peptide inhibitors of human pro-survival protein Bcl-xL.
Dutta S; Ryan J; Chen TS; Kougentakis C; Letai A; Keating AE
J Mol Biol; 2015 Mar; 427(6 Pt B):1241-1253. PubMed ID: 25451027
[TBL] [Abstract][Full Text] [Related]
18. Experimental Characterization of the Binding Affinities between Proapoptotic BH3 Peptides and Antiapoptotic Bcl-2 Proteins.
Kong W; Zhou M; Li Q; Fan W; Lin H; Wang R
ChemMedChem; 2018 Sep; 13(17):1763-1770. PubMed ID: 30084216
[TBL] [Abstract][Full Text] [Related]
19. Tipping the Noxa/Mcl-1 balance overcomes ABT-737 resistance in chronic lymphocytic leukemia.
Tromp JM; Geest CR; Breij EC; Elias JA; van Laar J; Luijks DM; Kater AP; Beaumont T; van Oers MH; Eldering E
Clin Cancer Res; 2012 Jan; 18(2):487-98. PubMed ID: 22128299
[TBL] [Abstract][Full Text] [Related]
20. A novel BH3 mimetic efficiently induces apoptosis in melanoma cells through direct binding to anti-apoptotic Bcl-2 family proteins, including phosphorylated Mcl-1.
Liu Y; Xie M; Song T; Sheng H; Yu X; Zhang Z
Pigment Cell Melanoma Res; 2015 Mar; 28(2):161-70. PubMed ID: 25324174
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
