200 related articles for article (PubMed ID: 28026167)
1. Heat Capacity Changes for Transition-State Analogue Binding and Catalysis with Human 5'-Methylthioadenosine Phosphorylase.
Firestone RS; Cameron SA; Karp JM; Arcus VL; Schramm VL
ACS Chem Biol; 2017 Feb; 12(2):464-473. PubMed ID: 28026167
[TBL] [Abstract][Full Text] [Related]
2. Entropy-driven binding of picomolar transition state analogue inhibitors to human 5'-methylthioadenosine phosphorylase.
Guan R; Ho MC; Brenowitz M; Tyler PC; Evans GB; Almo SC; Schramm VL
Biochemistry; 2011 Nov; 50(47):10408-17. PubMed ID: 21985704
[TBL] [Abstract][Full Text] [Related]
3. Thermodynamic analysis of transition-state features in picomolar inhibitors of human 5'-methylthioadenosine phosphorylase.
Guan R; Tyler PC; Evans GB; Schramm VL
Biochemistry; 2013 Nov; 52(46):8313-22. PubMed ID: 24148083
[TBL] [Abstract][Full Text] [Related]
4. Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A.
Singh V; Shi W; Evans GB; Tyler PC; Furneaux RH; Almo SC; Schramm VL
Biochemistry; 2004 Jan; 43(1):9-18. PubMed ID: 14705926
[TBL] [Abstract][Full Text] [Related]
5. A transition state analogue of 5'-methylthioadenosine phosphorylase induces apoptosis in head and neck cancers.
Basu I; Cordovano G; Das I; Belbin TJ; Guha C; Schramm VL
J Biol Chem; 2007 Jul; 282(29):21477-86. PubMed ID: 17548352
[TBL] [Abstract][Full Text] [Related]
6. The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A resolution provides insights into substrate binding and catalysis.
Appleby TC; Erion MD; Ealick SE
Structure; 1999 Jun; 7(6):629-41. PubMed ID: 10404592
[TBL] [Abstract][Full Text] [Related]
7. Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues.
Rinaldo-Matthis A; Wing C; Ghanem M; Deng H; Wu P; Gupta A; Tyler PC; Evans GB; Furneaux RH; Almo SC; Wang CC; Schramm VL
Biochemistry; 2007 Jan; 46(3):659-68. PubMed ID: 17223688
[TBL] [Abstract][Full Text] [Related]
8. Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
Lee JE; Singh V; Evans GB; Tyler PC; Furneaux RH; Cornell KA; Riscoe MK; Schramm VL; Howell PL
J Biol Chem; 2005 May; 280(18):18274-82. PubMed ID: 15746096
[TBL] [Abstract][Full Text] [Related]
9. Transition state analogues in quorum sensing and SAM recycling.
Schramm VL; Gutierrez JA; Cordovano G; Basu I; Guha C; Belbin TJ; Evans GB; Tyler PC; Furneaux RH
Nucleic Acids Symp Ser (Oxf); 2008; (52):75-6. PubMed ID: 18776260
[TBL] [Abstract][Full Text] [Related]
10. Selective Inhibitors of Helicobacter pylori Methylthioadenosine Nucleosidase and Human Methylthioadenosine Phosphorylase.
Harijan RK; Hoff O; Ducati RG; Firestone RS; Hirsch BM; Evans GB; Schramm VL; Tyler PC
J Med Chem; 2019 Apr; 62(7):3286-3296. PubMed ID: 30860833
[TBL] [Abstract][Full Text] [Related]
11. Femtomolar transition state analogue inhibitors of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli.
Singh V; Evans GB; Lenz DH; Mason JM; Clinch K; Mee S; Painter GF; Tyler PC; Furneaux RH; Lee JE; Howell PL; Schramm VL
J Biol Chem; 2005 May; 280(18):18265-73. PubMed ID: 15749708
[TBL] [Abstract][Full Text] [Related]
12. Transition state analogue of MTAP extends lifespan of APC
Firestone RS; Feng M; Basu I; Peregrina K; Augenlicht LH; Schramm VL
Sci Rep; 2021 Apr; 11(1):8844. PubMed ID: 33893330
[TBL] [Abstract][Full Text] [Related]
13. Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae.
Singh V; Shi W; Almo SC; Evans GB; Furneaux RH; Tyler PC; Painter GF; Lenz DH; Mee S; Zheng R; Schramm VL
Biochemistry; 2006 Oct; 45(43):12929-41. PubMed ID: 17059210
[TBL] [Abstract][Full Text] [Related]
14. Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase.
Basu I; Locker J; Cassera MB; Belbin TJ; Merino EF; Dong X; Hemeon I; Evans GB; Guha C; Schramm VL
J Biol Chem; 2011 Feb; 286(6):4902-11. PubMed ID: 21135097
[TBL] [Abstract][Full Text] [Related]
15. Catalytic site cooperativity in dimeric methylthioadenosine nucleosidase.
Wang S; Thomas K; Schramm VL
Biochemistry; 2014 Mar; 53(9):1527-35. PubMed ID: 24502544
[TBL] [Abstract][Full Text] [Related]
16. Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase.
Evans GB; Furneaux RH; Lenz DH; Painter GF; Schramm VL; Singh V; Tyler PC
J Med Chem; 2005 Jul; 48(14):4679-89. PubMed ID: 16000004
[TBL] [Abstract][Full Text] [Related]
17. The effect of a novel transition state inhibitor of methylthioadenosine phosphorylase on pemetrexed activity.
Chattopadhyay S; Zhao R; Tsai E; Schramm VL; Goldman ID
Mol Cancer Ther; 2006 Oct; 5(10):2549-55. PubMed ID: 17041099
[TBL] [Abstract][Full Text] [Related]
18. Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase.
Lewandowicz A; Shi W; Evans GB; Tyler PC; Furneaux RH; Basso LA; Santos DS; Almo SC; Schramm VL
Biochemistry; 2003 May; 42(20):6057-66. PubMed ID: 12755607
[TBL] [Abstract][Full Text] [Related]
19. Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase.
Evans GB; Furneaux RH; Schramm VL; Singh V; Tyler PC
J Med Chem; 2004 Jun; 47(12):3275-81. PubMed ID: 15163207
[TBL] [Abstract][Full Text] [Related]
20. Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition.
Taylor EA; Rinaldo-Matthis A; Li L; Ghanem M; Hazleton KZ; Cassera MB; Almo SC; Schramm VL
Biochemistry; 2007 Oct; 46(43):12405-15. PubMed ID: 17918964
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]