BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

266 related articles for article (PubMed ID: 28028034)

  • 1. Rapamycin-insensitive companion of mTOR (RICTOR) amplification defines a subset of advanced gastric cancer and is sensitive to AZD2014-mediated mTORC1/2 inhibition.
    Kim ST; Kim SY; Klempner SJ; Yoon J; Kim N; Ahn S; Bang H; Kim KM; Park W; Park SH; Park JO; Park YS; Lim HY; Lee SH; Park K; Kang WK; Lee J
    Ann Oncol; 2017 Mar; 28(3):547-554. PubMed ID: 28028034
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RICTOR amplification identifies a subgroup in small cell lung cancer and predicts response to drugs targeting mTOR.
    Sakre N; Wildey G; Behtaj M; Kresak A; Yang M; Fu P; Dowlati A
    Oncotarget; 2017 Jan; 8(4):5992-6002. PubMed ID: 27863413
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Correlation between RICTOR overexpression and amplification in advanced solid tumors.
    Bang H; Ahn S; Ji Kim E; Kim ST; Park HY; Lee J; Kim KM
    Pathol Res Pract; 2020 Jan; 216(1):152734. PubMed ID: 31740232
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells.
    Jiang S; Zou Z; Nie P; Wen R; Xiao Y; Tang J
    PLoS One; 2015; 10(7):e0132880. PubMed ID: 26176608
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AZD2014, an Inhibitor of mTORC1 and mTORC2, Is Highly Effective in ER+ Breast Cancer When Administered Using Intermittent or Continuous Schedules.
    Guichard SM; Curwen J; Bihani T; D'Cruz CM; Yates JW; Grondine M; Howard Z; Davies BR; Bigley G; Klinowska T; Pike KG; Pass M; Chresta CM; Polanska UM; McEwen R; Delpuech O; Green S; Cosulich SC
    Mol Cancer Ther; 2015 Nov; 14(11):2508-18. PubMed ID: 26358751
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Unmasking the impact of Rictor in cancer: novel insights of mTORC2 complex.
    Gkountakos A; Pilotto S; Mafficini A; Vicentini C; Simbolo M; Milella M; Tortora G; Scarpa A; Bria E; Corbo V
    Carcinogenesis; 2018 Jul; 39(8):971-980. PubMed ID: 29955840
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Correlation between immunohistochemistry and RICTOR fluorescence in situ hybridization amplification in small cell lung carcinoma.
    Krencz I; Sebestyen A; Papay J; Lou Y; Lutz GF; Majewicz TL; Khoor A
    Hum Pathol; 2019 Nov; 93():74-80. PubMed ID: 31454632
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RICTOR Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 Inhibitors.
    Cheng H; Zou Y; Ross JS; Wang K; Liu X; Halmos B; Ali SM; Liu H; Verma A; Montagna C; Chachoua A; Goel S; Schwartz EL; Zhu C; Shan J; Yu Y; Gritsman K; Yelensky R; Lipson D; Otto G; Hawryluk M; Stephens PJ; Miller VA; Piperdi B; Perez-Soler R
    Cancer Discov; 2015 Dec; 5(12):1262-70. PubMed ID: 26370156
    [TBL] [Abstract][Full Text] [Related]  

  • 9. mTOR hyperactivity and
    Sztankovics D; Moldvai D; Petővári G; Dankó T; Szalai F; Miyaura R; Varga V; Nagy N; Papp G; Pápay J; Krencz I; Sebestyén A
    Pathol Oncol Res; 2024; 30():1611643. PubMed ID: 38515456
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel RICTOR amplification harbouring entities: FISH validation of RICTOR amplification in tumour tissue after next-generation sequencing.
    Sztankovics D; Krencz I; Moldvai D; Dankó T; Nagy Á; Nagy N; Bedics G; Rókusz A; Papp G; Tőkés AM; Pápay J; Sápi Z; Dezső K; Bödör C; Sebestyén A
    Sci Rep; 2023 Nov; 13(1):19610. PubMed ID: 37949943
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting of mTORC2 may have advantages over selective targeting of mTORC1 in the treatment of malignant pheochromocytoma.
    Zhang X; Wang X; Xu T; Zhong S; Shen Z
    Tumour Biol; 2015 Jul; 36(7):5273-81. PubMed ID: 25666752
    [TBL] [Abstract][Full Text] [Related]  

  • 12.
    Kim LC; Rhee CH; Chen J
    Mol Cancer Res; 2020 Nov; 18(11):1675-1684. PubMed ID: 32801163
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Potent antitumour of the mTORC1/2 dual inhibitor AZD2014 in docetaxel-sensitive and docetaxel-resistant castration-resistant prostate cancer cells.
    Li S; Sheng J; Liu Z; Fan Y; Zhang C; Lv T; Hu S; Jin J; Yu W; Song Y
    J Cell Mol Med; 2021 Mar; 25(5):2436-2449. PubMed ID: 33507584
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of PI3K-Akt-mTOR signaling in glioblastoma by mTORC1/2 inhibitors.
    Fan QW; Weiss WA
    Methods Mol Biol; 2012; 821():349-59. PubMed ID: 22125077
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
    Morrison Joly M; Williams MM; Hicks DJ; Jones B; Sanchez V; Young CD; Sarbassov DD; Muller WJ; Brantley-Sieders D; Cook RS
    Breast Cancer Res; 2017 Jun; 19(1):74. PubMed ID: 28666462
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Down-regulation of Rictor enhances cell sensitivity to PI3K inhibitor LY294002 by blocking mTORC2-medicated phosphorylation of Akt/PRAS40 in esophageal squamous cell carcinoma.
    Hou G; Zhao Q; Zhang M; Fan T; Liu M; Shi X; Ren Y; Wang Y; Zhou J; Lu Z
    Biomed Pharmacother; 2018 Oct; 106():1348-1356. PubMed ID: 30119206
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rictor promotes tumor progression of rapamycin-insensitive triple-negative breast cancer cells.
    Watanabe R; Miyata M; Oneyama C
    Biochem Biophys Res Commun; 2020 Oct; 531(4):636-642. PubMed ID: 32819718
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Preclinical analysis of MTOR complex 1/2 inhibition in diffuse intrinsic pontine glioma.
    Flannery PC; DeSisto JA; Amani V; Venkataraman S; Lemma RT; Prince EW; Donson A; Moroze EE; Hoffman L; Levy JMM; Foreman N; Vibhakar R; Green AL
    Oncol Rep; 2018 Feb; 39(2):455-464. PubMed ID: 29207163
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential roles and activation of mammalian target of rapamycin complexes 1 and 2 during cell migration in prostate cancer cells.
    Venugopal SV; Caggia S; Gambrell-Sanders D; Khan SA
    Prostate; 2020 Apr; 80(5):412-423. PubMed ID: 31995655
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dual inhibition of the PI3K/AKT/mTOR pathway suppresses the growth of leiomyosarcomas but leads to ERK activation through mTORC2: biological and clinical implications.
    Fourneaux B; Chaire V; Lucchesi C; Karanian M; Pineau R; Laroche-Clary A; Italiano A
    Oncotarget; 2017 Jan; 8(5):7878-7890. PubMed ID: 28002802
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.