BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

521 related articles for article (PubMed ID: 28034647)

  • 1. Synthesis and biological evaluation of cis-restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers.
    Subba Rao AV; Swapna K; Shaik SP; Lakshma Nayak V; Srinivasa Reddy T; Sunkari S; Shaik TB; Bagul C; Kamal A
    Bioorg Med Chem; 2017 Feb; 25(3):977-999. PubMed ID: 28034647
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design and synthesis of cis-restricted benzimidazole and benzothiazole mimics of combretastatin A-4 as antimitotic agents with apoptosis inducing ability.
    Ashraf M; Shaik TB; Malik MS; Syed R; Mallipeddi PL; Vardhan MVPSV; Kamal A
    Bioorg Med Chem Lett; 2016 Sep; 26(18):4527-4535. PubMed ID: 27515320
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1,2,4-triazoles as potential combretastatin analogues.
    Mustafa M; Abdelhamid D; Abdelhafez EMN; Ibrahim MAA; Gamal-Eldeen AM; Aly OM
    Eur J Med Chem; 2017 Dec; 141():293-305. PubMed ID: 29031074
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of 1,2,3-triazole linked aminocombretastatin conjugates as mitochondrial mediated apoptosis inducers.
    Kamal A; Shaik B; Nayak VL; Nagaraju B; Kapure JS; Shaheer Malik M; Shaik TB; Prasad B
    Bioorg Med Chem; 2014 Oct; 22(19):5155-67. PubMed ID: 25192811
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of arylcinnamide linked combretastatin-A4 hybrids as tubulin polymerization inhibitors and apoptosis inducing agents.
    Kamal A; Bajee S; Lakshma Nayak V; Venkata Subba Rao A; Nagaraju B; Ratna Reddy C; Jeevak Sopanrao K; Alarifi A
    Bioorg Med Chem Lett; 2016 Jun; 26(12):2957-2964. PubMed ID: 27161282
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Combretastatin linked 1,3,4-oxadiazole conjugates as a Potent Tubulin Polymerization inhibitors.
    Kamal A; Srikanth PS; Vishnuvardhan MV; Kumar GB; Suresh Babu K; Hussaini SM; Kapure JS; Alarifi A
    Bioorg Chem; 2016 Apr; 65():126-36. PubMed ID: 26943479
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Potent combretastatin A-4 analogs containing 1,2,4-triazole: Synthesis, antiproliferative, anti-tubulin activity, and docking study.
    Mustafa M; Anwar S; Elgamal F; Ahmed ER; Aly OM
    Eur J Med Chem; 2019 Dec; 183():111697. PubMed ID: 31536891
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and synthesis of 1,2,3-triazolo linked benzo[d]imidazo[2,1-b]thiazole conjugates as tubulin polymerization inhibitors.
    Shaik SP; Vishnuvardhan MVPS; Sultana F; Subba Rao AV; Bagul C; Bhattacharjee D; Kapure JS; Jain N; Kamal A
    Bioorg Med Chem; 2017 Jul; 25(13):3285-3297. PubMed ID: 28462842
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of pyrimidine bridged combretastatin derivatives as potential anticancer agents and mechanistic studies.
    Kumar B; Sharma P; Gupta VP; Khullar M; Singh S; Dogra N; Kumar V
    Bioorg Chem; 2018 Aug; 78():130-140. PubMed ID: 29554587
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines.
    Demchuk DV; Samet AV; Chernysheva NB; Ushkarov VI; Stashina GA; Konyushkin LD; Raihstat MM; Firgang SI; Philchenkov AA; Zavelevich MP; Kuiava LM; Chekhun VF; Blokhin DY; Kiselyov AS; Semenova MN; Semenov VV
    Bioorg Med Chem; 2014 Jan; 22(2):738-55. PubMed ID: 24387982
    [TBL] [Abstract][Full Text] [Related]  

  • 11. New Combretastatin Analogs as Anticancer Agents: Design, Synthesis, Microtubules Polymerization Inhibition, and Molecular Docking Studies.
    Abdul Hussein SA; Razzak Mahmood AA; Tahtamouni LH; Balakit AA; Yaseen YS; Al-Hasani RA
    Chem Biodivers; 2023 Apr; 20(4):e202201206. PubMed ID: 36890635
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular diversity of trimethoxyphenyl-1,2,3-triazole hybrids as novel colchicine site tubulin polymerization inhibitors.
    Fu DJ; Li P; Wu BW; Cui XX; Zhao CB; Zhang SY
    Eur J Med Chem; 2019 Mar; 165():309-322. PubMed ID: 30690300
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues.
    Romagnoli R; Baraldi PG; Cruz-Lopez O; Lopez Cara C; Carrion MD; Brancale A; Hamel E; Chen L; Bortolozzi R; Basso G; Viola G
    J Med Chem; 2010 May; 53(10):4248-58. PubMed ID: 20420439
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V; Pindiprolu SKSS; Sana S; Ramamurty DSVNM; Madasi JRK; Vadlamani S
    Anticancer Agents Med Chem; 2021; 21(8):1047-1055. PubMed ID: 32981511
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of 1-(benzofuran-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-1,2,3-triazole derivatives as tubulin polymerization inhibitors.
    Qi ZY; Hao SY; Tian HZ; Bian HL; Hui L; Chen SW
    Bioorg Chem; 2020 Jan; 94():103392. PubMed ID: 31669093
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Correlation of hydrogen-bonding propensity and anticancer profile of tetrazole-tethered combretastatin analogues.
    Jedhe GS; Paul D; Gonnade RG; Santra MK; Hamel E; Nguyen TL; Sanjayan GJ
    Bioorg Med Chem Lett; 2013 Aug; 23(16):4680-4. PubMed ID: 23809851
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH; Dahab MA; Ibrahim MK; Alsaif NA; Alanazi AZ; Eissa SI; Mehany ABM; Beauchemin AM
    Bioorg Chem; 2021 Jul; 112():104965. PubMed ID: 34020238
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 3-substituted 2-phenylimidazo[2,1-b]benzothiazoles: synthesis, anticancer activity, and inhibition of tubulin polymerization.
    Kamal A; Sultana F; Ramaiah MJ; Srikanth YV; Viswanath A; Kishor C; Sharma P; Pushpavalli SN; Addlagatta A; Pal-Bhadra M
    ChemMedChem; 2012 Feb; 7(2):292-300. PubMed ID: 22241597
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and biological evaluation of novel alkylsulfanyl-1,2,4-triazoles as cis-restricted combretastatin A-4 analogues.
    Li YH; Zhang B; Yang HK; Li Q; Diao PC; You WW; Zhao PL
    Eur J Med Chem; 2017 Jan; 125():1098-1106. PubMed ID: 27810596
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of 1-benzyl-N-(2-(phenylamino)pyridin-3-yl)-1H-1,2,3-triazole-4-carboxamides as antimitotic agents.
    Prasad B; Lakshma Nayak V; Srikanth PS; Baig MF; Subba Reddy NV; Babu KS; Kamal A
    Bioorg Chem; 2019 Mar; 83():535-548. PubMed ID: 30472555
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.