258 related articles for article (PubMed ID: 28035068)
1. Otub1 stabilizes MDMX and promotes its proapoptotic function at the mitochondria.
Chen Y; Wang YG; Li Y; Sun XX; Dai MS
Oncotarget; 2017 Feb; 8(7):11053-11062. PubMed ID: 28035068
[TBL] [Abstract][Full Text] [Related]
2. Monoubiquitination is critical for ovarian tumor domain-containing ubiquitin aldehyde binding protein 1 (Otub1) to suppress UbcH5 enzyme and stabilize p53 protein.
Li Y; Sun XX; Elferich J; Shinde U; David LL; Dai MS
J Biol Chem; 2014 Feb; 289(8):5097-108. PubMed ID: 24403071
[TBL] [Abstract][Full Text] [Related]
3. Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1.
Sun XX; Challagundla KB; Dai MS
EMBO J; 2012 Feb; 31(3):576-92. PubMed ID: 22124327
[TBL] [Abstract][Full Text] [Related]
4. MdmX is a substrate for the deubiquitinating enzyme USP2a.
Allende-Vega N; Sparks A; Lane DP; Saville MK
Oncogene; 2010 Jan; 29(3):432-41. PubMed ID: 19838211
[TBL] [Abstract][Full Text] [Related]
5. Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1.
Sun XX; Dai MS
World J Biol Chem; 2014 May; 5(2):75-84. PubMed ID: 24920999
[TBL] [Abstract][Full Text] [Related]
6. Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase.
Okamoto K; Taya Y; Nakagama H
FEBS Lett; 2009 Sep; 583(17):2710-4. PubMed ID: 19619542
[TBL] [Abstract][Full Text] [Related]
7. Elevated MDM2 boosts the apoptotic activity of p53-MDM2 binding inhibitors by facilitating MDMX degradation.
Xia M; Knezevic D; Tovar C; Huang B; Heimbrook DC; Vassilev LT
Cell Cycle; 2008 Jun; 7(11):1604-12. PubMed ID: 18520179
[TBL] [Abstract][Full Text] [Related]
8. MdmX protein is essential for Mdm2 protein-mediated p53 polyubiquitination.
Wang X; Wang J; Jiang X
J Biol Chem; 2011 Jul; 286(27):23725-34. PubMed ID: 21572037
[TBL] [Abstract][Full Text] [Related]
9. Regulation of p53: a collaboration between Mdm2 and Mdmx.
Pei D; Zhang Y; Zheng J
Oncotarget; 2012 Mar; 3(3):228-35. PubMed ID: 22410433
[TBL] [Abstract][Full Text] [Related]
10. A site-directed mutagenesis study of the MdmX RING domain.
Egorova O; Mis M; Sheng Y
Biochem Biophys Res Commun; 2014 May; 447(4):696-701. PubMed ID: 24755078
[TBL] [Abstract][Full Text] [Related]
11. Mdmx promotes genomic instability independent of p53 and Mdm2.
Carrillo AM; Bouska A; Arrate MP; Eischen CM
Oncogene; 2015 Feb; 34(7):846-56. PubMed ID: 24608433
[TBL] [Abstract][Full Text] [Related]
12. The p53 orchestra: Mdm2 and Mdmx set the tone.
Wade M; Wang YV; Wahl GM
Trends Cell Biol; 2010 May; 20(5):299-309. PubMed ID: 20172729
[TBL] [Abstract][Full Text] [Related]
13. MDM2, MDMX, and p73 regulate cell-cycle progression in the absence of wild-type p53.
Klein AM; Biderman L; Tong D; Alaghebandan B; Plumber SA; Mueller HS; van Vlimmeren A; Katz C; Prives C
Proc Natl Acad Sci U S A; 2021 Nov; 118(44):. PubMed ID: 34716260
[TBL] [Abstract][Full Text] [Related]
14. MDM2 promotes ubiquitination and degradation of MDMX.
Pan Y; Chen J
Mol Cell Biol; 2003 Aug; 23(15):5113-21. PubMed ID: 12860999
[TBL] [Abstract][Full Text] [Related]
15. Context-dependent roles of MDMX (MDM4) and MDM2 in breast cancer proliferation and circulating tumor cells.
Gao C; Xiao G; Piersigilli A; Gou J; Ogunwobi O; Bargonetti J
Breast Cancer Res; 2019 Jan; 21(1):5. PubMed ID: 30642351
[TBL] [Abstract][Full Text] [Related]
16. DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.
Okamoto K; Kashima K; Pereg Y; Ishida M; Yamazaki S; Nota A; Teunisse A; Migliorini D; Kitabayashi I; Marine JC; Prives C; Shiloh Y; Jochemsen AG; Taya Y
Mol Cell Biol; 2005 Nov; 25(21):9608-20. PubMed ID: 16227609
[TBL] [Abstract][Full Text] [Related]
17. Ubiquitin-specific protease 2a stabilizes MDM4 and facilitates the p53-mediated intrinsic apoptotic pathway in glioblastoma.
Wang CL; Wang JY; Liu ZY; Ma XM; Wang XW; Jin H; Zhang XP; Fu D; Hou LJ; Lu YC
Carcinogenesis; 2014 Jul; 35(7):1500-9. PubMed ID: 24445145
[TBL] [Abstract][Full Text] [Related]
18. Cisplatin causes cell death via TAB1 regulation of p53/MDM2/MDMX circuitry.
Zhu Y; Regunath K; Jacq X; Prives C
Genes Dev; 2013 Aug; 27(16):1739-51. PubMed ID: 23934659
[TBL] [Abstract][Full Text] [Related]
19. AXL receptor signalling suppresses p53 in melanoma through stabilization of the MDMX-MDM2 complex.
de Polo A; Luo Z; Gerarduzzi C; Chen X; Little JB; Yuan ZM
J Mol Cell Biol; 2017 Apr; 9(2):154-165. PubMed ID: 27927748
[TBL] [Abstract][Full Text] [Related]
20. Inferring Leading Interactions in the p53/Mdm2/Mdmx Circuit through Live-Cell Imaging and Modeling.
Heltberg ML; Chen SH; Jiménez A; Jambhekar A; Jensen MH; Lahav G
Cell Syst; 2019 Dec; 9(6):548-558.e5. PubMed ID: 31812692
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
