BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

304 related articles for article (PubMed ID: 28039480)

  • 1. Nutrient-induced FNIP degradation by SCFβ-TRCP regulates FLCN complex localization and promotes renal cancer progression.
    Nagashima K; Fukushima H; Shimizu K; Yamada A; Hidaka M; Hasumi H; Ikebe T; Fukumoto S; Okabe K; Inuzuka H
    Oncotarget; 2017 Feb; 8(6):9947-9960. PubMed ID: 28039480
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Birt-Hogg-Dubé syndrome: Clinical and molecular aspects of recently identified kidney cancer syndrome.
    Hasumi H; Baba M; Hasumi Y; Furuya M; Yao M
    Int J Urol; 2016 Mar; 23(3):204-10. PubMed ID: 26608100
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interaction of folliculin (Birt-Hogg-Dubé gene product) with a novel Fnip1-like (FnipL/Fnip2) protein.
    Takagi Y; Kobayashi T; Shiono M; Wang L; Piao X; Sun G; Zhang D; Abe M; Hagiwara Y; Takahashi K; Hino O
    Oncogene; 2008 Sep; 27(40):5339-47. PubMed ID: 18663353
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn.
    Hasumi H; Baba M; Hasumi Y; Lang M; Huang Y; Oh HF; Matsuo M; Merino MJ; Yao M; Ito Y; Furuya M; Iribe Y; Kodama T; Southon E; Tessarollo L; Nagashima K; Haines DC; Linehan WM; Schmidt LS
    Proc Natl Acad Sci U S A; 2015 Mar; 112(13):E1624-31. PubMed ID: 25775561
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Folliculin variants linked to Birt-Hogg-Dubé syndrome are targeted for proteasomal degradation.
    Clausen L; Stein A; Grønbæk-Thygesen M; Nygaard L; Søltoft CL; Nielsen SV; Lisby M; Ravid T; Lindorff-Larsen K; Hartmann-Petersen R
    PLoS Genet; 2020 Nov; 16(11):e1009187. PubMed ID: 33137092
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification and characterization of a novel folliculin-interacting protein FNIP2.
    Hasumi H; Baba M; Hong SB; Hasumi Y; Huang Y; Yao M; Valera VA; Linehan WM; Schmidt LS
    Gene; 2008 May; 415(1-2):60-7. PubMed ID: 18403135
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development.
    Baba M; Keller JR; Sun HW; Resch W; Kuchen S; Suh HC; Hasumi H; Hasumi Y; Kieffer-Kwon KR; Gonzalez CG; Hughes RM; Klein ME; Oh HF; Bible P; Southon E; Tessarollo L; Schmidt LS; Linehan WM; Casellas R
    Blood; 2012 Aug; 120(6):1254-61. PubMed ID: 22709692
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling.
    Baba M; Hong SB; Sharma N; Warren MB; Nickerson ML; Iwamatsu A; Esposito D; Gillette WK; Hopkins RF; Hartley JL; Furihata M; Oishi S; Zhen W; Burke TR; Linehan WM; Schmidt LS; Zbar B
    Proc Natl Acad Sci U S A; 2006 Oct; 103(42):15552-7. PubMed ID: 17028174
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Renal tumour suppressor function of the Birt-Hogg-Dubé syndrome gene product folliculin.
    Hudon V; Sabourin S; Dydensborg AB; Kottis V; Ghazi A; Paquet M; Crosby K; Pomerleau V; Uetani N; Pause A
    J Med Genet; 2010 Mar; 47(3):182-9. PubMed ID: 19843504
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia.
    Chen J; Futami K; Petillo D; Peng J; Wang P; Knol J; Li Y; Khoo SK; Huang D; Qian CN; Zhao P; Dykema K; Zhang R; Cao B; Yang XJ; Furge K; Williams BO; Teh BT
    PLoS One; 2008; 3(10):e3581. PubMed ID: 18974783
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation.
    Dunlop EA; Seifan S; Claessens T; Behrends C; Kamps MA; Rozycka E; Kemp AJ; Nookala RK; Blenis J; Coull BJ; Murray JT; van Steensel MA; Wilkinson S; Tee AR
    Autophagy; 2014 Oct; 10(10):1749-60. PubMed ID: 25126726
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Establishment and characterization of BHD-F59RSVT, an immortalized cell line derived from a renal cell carcinoma in a patient with Birt-Hogg-Dubé syndrome.
    Furuya M; Hasumi H; Baba M; Tanaka R; Iribe Y; Onishi T; Nagashima Y; Nakatani Y; Isono Y; Yao M
    Lab Invest; 2017 Mar; 97(3):343-351. PubMed ID: 27991910
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Flcn-deficient renal cells are tumorigenic and sensitive to mTOR suppression.
    Wu M; Si S; Li Y; Schoen S; Xiao GQ; Li X; Teh BT; Wu G; Chen J
    Oncotarget; 2015 Oct; 6(32):32761-73. PubMed ID: 26418749
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Distinctive expression patterns of glycoprotein non-metastatic B and folliculin in renal tumors in patients with Birt-Hogg-Dubé syndrome.
    Furuya M; Hong SB; Tanaka R; Kuroda N; Nagashima Y; Nagahama K; Suyama T; Yao M; Nakatani Y
    Cancer Sci; 2015 Mar; 106(3):315-23. PubMed ID: 25594584
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Knockdown of Slingshot 2 (SSH2) serine phosphatase induces Caspase3 activation in human carcinoma cell lines with the loss of the Birt-Hogg-Dubé tumour suppressor gene (FLCN).
    Lu X; Boora U; Seabra L; Rabai EM; Fenton J; Reiman A; Nagy Z; Maher ER
    Oncogene; 2014 Feb; 33(8):956-65. PubMed ID: 23416984
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Birt-Hogg-Dube syndrome: clinicopathological features of the lung.
    Furuya M; Nakatani Y
    J Clin Pathol; 2013 Mar; 66(3):178-86. PubMed ID: 23223565
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Birt-Hogg-Dubé syndrome: from gene discovery to molecularly targeted therapies.
    Schmidt LS
    Fam Cancer; 2013 Sep; 12(3):357-64. PubMed ID: 23108783
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FLCN: The causative gene for Birt-Hogg-Dubé syndrome.
    Schmidt LS; Linehan WM
    Gene; 2018 Jan; 640():28-42. PubMed ID: 28970150
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of a splice-site mutation in the tumor suppressor gene FLCN associated with renal cancer.
    Bartram MP; Mishra T; Reintjes N; Fabretti F; Gharbi H; Adam AC; Göbel H; Franke M; Schermer B; Haneder S; Benzing T; Beck BB; Müller RU
    BMC Med Genet; 2017 May; 18(1):53. PubMed ID: 28499369
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Disruption of tubular Flcn expression as a mouse model for renal tumor induction.
    Chen J; Huang D; Rubera I; Futami K; Wang P; Zickert P; Khoo SK; Dykema K; Zhao P; Petillo D; Cao B; Zhang Z; Si S; Schoen SR; Yang XJ; Zhou M; Xiao GQ; Wu G; Nordenskjöld M; Tauc M; Williams BO; Furge KA; Teh BT
    Kidney Int; 2015 Nov; 88(5):1057-69. PubMed ID: 26083655
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.