BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 28039913)

  • 1. The unfolded protein response mediates fibrogenesis and collagen I secretion through regulating TANGO1 in mice.
    Maiers JL; Kostallari E; Mushref M; deAssuncao TM; Li H; Jalan-Sakrikar N; Huebert RC; Cao S; Malhi H; Shah VH
    Hepatology; 2017 Mar; 65(3):983-998. PubMed ID: 28039913
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Coordinated signaling of activating transcription factor 6α and inositol-requiring enzyme 1α regulates hepatic stellate cell-mediated fibrogenesis in mice.
    Xue F; Lu J; Buchl SC; Sun L; Shah VH; Malhi H; Maiers JL
    Am J Physiol Gastrointest Liver Physiol; 2021 May; 320(5):G864-G879. PubMed ID: 33728997
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transforming growth factor β (TGFβ) cross-talk with the unfolded protein response is critical for hepatic stellate cell activation.
    Liu Z; Li C; Kang N; Malhi H; Shah VH; Maiers JL
    J Biol Chem; 2019 Mar; 294(9):3137-3151. PubMed ID: 30610118
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The XBP1 Arm of the Unfolded Protein Response Induces Fibrogenic Activity in Hepatic Stellate Cells Through Autophagy.
    Kim RS; Hasegawa D; Goossens N; Tsuchida T; Athwal V; Sun X; Robinson CL; Bhattacharya D; Chou HI; Zhang DY; Fuchs BC; Lee Y; Hoshida Y; Friedman SL
    Sci Rep; 2016 Dec; 6():39342. PubMed ID: 27996033
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy.
    Hernández-Gea V; Hilscher M; Rozenfeld R; Lim MP; Nieto N; Werner S; Devi LA; Friedman SL
    J Hepatol; 2013 Jul; 59(1):98-104. PubMed ID: 23485523
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CCN1/CYR61 overexpression in hepatic stellate cells induces ER stress-related apoptosis.
    Borkham-Kamphorst E; Steffen BT; Van de Leur E; Haas U; Tihaa L; Friedman SL; Weiskirchen R
    Cell Signal; 2016 Jan; 28(1):34-42. PubMed ID: 26515130
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endoplasmic Reticulum Stress in Hepatic Stellate Cells Promotes Liver Fibrosis via PERK-Mediated Degradation of HNRNPA1 and Up-regulation of SMAD2.
    Koo JH; Lee HJ; Kim W; Kim SG
    Gastroenterology; 2016 Jan; 150(1):181-193.e8. PubMed ID: 26435271
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Unfolded protein response is an early, non-critical event during hepatic stellate cell activation.
    Mannaerts I; Thoen LFR; Eysackers N; Cubero FJ; Batista Leite S; Coldham I; Colle I; Trautwein C; van Grunsven LA
    Cell Death Dis; 2019 Feb; 10(2):98. PubMed ID: 30718473
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aryl Hydrocarbon Receptor Signaling Prevents Activation of Hepatic Stellate Cells and Liver Fibrogenesis in Mice.
    Yan J; Tung HC; Li S; Niu Y; Garbacz WG; Lu P; Bi Y; Li Y; He J; Xu M; Ren S; Monga SP; Schwabe RF; Yang D; Xie W
    Gastroenterology; 2019 Sep; 157(3):793-806.e14. PubMed ID: 31170413
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Unfolded protein response induced by Brefeldin A increases collagen type I levels in hepatic stellate cells through an IRE1α, p38 MAPK and Smad-dependent pathway.
    de Galarreta MR; Navarro A; Ansorena E; Garzón AG; Mòdol T; López-Zabalza MJ; Martínez-Irujo JJ; Iraburu MJ
    Biochim Biophys Acta; 2016 Aug; 1863(8):2115-23. PubMed ID: 27155082
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fibromodulin, an oxidative stress-sensitive proteoglycan, regulates the fibrogenic response to liver injury in mice.
    Mormone E; Lu Y; Ge X; Fiel MI; Nieto N
    Gastroenterology; 2012 Mar; 142(3):612-621.e5. PubMed ID: 22138190
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin α(V)β(3) engagement and PI3K/pAkt/NFκB signaling.
    Urtasun R; Lopategi A; George J; Leung TM; Lu Y; Wang X; Ge X; Fiel MI; Nieto N
    Hepatology; 2012 Feb; 55(2):594-608. PubMed ID: 21953216
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibitory effects of microRNA 19b in hepatic stellate cell-mediated fibrogenesis.
    Lakner AM; Steuerwald NM; Walling TL; Ghosh S; Li T; McKillop IH; Russo MW; Bonkovsky HL; Schrum LW
    Hepatology; 2012 Jul; 56(1):300-10. PubMed ID: 22278637
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TANGO1 and SEC12 are copackaged with procollagen I to facilitate the generation of large COPII carriers.
    Yuan L; Kenny SJ; Hemmati J; Xu K; Schekman R
    Proc Natl Acad Sci U S A; 2018 Dec; 115(52):E12255-E12264. PubMed ID: 30545919
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis.
    Tarrats N; Moles A; Morales A; García-Ruiz C; Fernández-Checa JC; Marí M
    Hepatology; 2011 Jul; 54(1):319-27. PubMed ID: 21523796
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stress and Liver Fibrogenesis: Understanding the Role and Regulation of Stress Response Pathways in Hepatic Stellate Cells.
    Hanquier Z; Misra J; Baxter R; Maiers JL
    Am J Pathol; 2023 Oct; 193(10):1363-1376. PubMed ID: 37422148
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TANGO1 recruits ERGIC membranes to the endoplasmic reticulum for procollagen export.
    Santos AJ; Raote I; Scarpa M; Brouwers N; Malhotra V
    Elife; 2015 Nov; 4():. PubMed ID: 26568311
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of phosphatidylinositol 3-kinase signaling in hepatic stellate cells blocks the progression of hepatic fibrosis.
    Son G; Hines IN; Lindquist J; Schrum LW; Rippe RA
    Hepatology; 2009 Nov; 50(5):1512-23. PubMed ID: 19790269
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Portal myofibroblasts are sensitive to CCN-mediated endoplasmic reticulum stress-related apoptosis with potential to attenuate biliary fibrogenesis.
    Borkham-Kamphorst E; Steffen BT; van de Leur E; Haas U; Weiskirchen R
    Cell Signal; 2018 Nov; 51():72-85. PubMed ID: 30044965
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deletion of the collagen-specific molecular chaperone Hsp47 causes endoplasmic reticulum stress-mediated apoptosis of hepatic stellate cells.
    Kawasaki K; Ushioda R; Ito S; Ikeda K; Masago Y; Nagata K
    J Biol Chem; 2015 Feb; 290(6):3639-46. PubMed ID: 25525267
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.